Bortezomib inhibits STAT5-dependent degradation of LEF-1, inducing granulocytic differentiation in congenital neutropenia CD34(+) cells

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Phosphorylated STAT5 regulates p53 expression via BRCA1/BARD1-NPM1 and MDM2.Severe congenital neutropenias.Role of CSF3R mutations in the pathomechanism of congenital neutropenia and secondary acute myeloid leukemia.Transcriptional Regulation of Emergency Granulopoiesis in Leukemia.

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Bortezomib inhibits STAT5-dependent degradation of LEF-1, inducing granulocytic differentiation in congenital neutropenia CD34(+) cells

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http://www.wikidata.org/entity/Q42061078

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2014 nî lūn-bûn

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

Bortezomib inhibits STAT5-depe ...... ital neutropenia CD34(+) cells

@en

Bortezomib inhibits STAT5-depe ...... ital neutropenia CD34(+) cells

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type

Item

label

Bortezomib inhibits STAT5-depe ...... ital neutropenia CD34(+) cells

@en

Bortezomib inhibits STAT5-depe ...... ital neutropenia CD34(+) cells

@nl

prefLabel

Bortezomib inhibits STAT5-depe ...... ital neutropenia CD34(+) cells

@en

Bortezomib inhibits STAT5-depe ...... ital neutropenia CD34(+) cells

@nl

P1476

Bortezomib inhibits STAT5-depe ...... ital neutropenia CD34(+) cells

@en

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Cornelia Zeidler

http://www.w3.org/2001/XMLSchema#string

Inna Kuznetsova

http://www.w3.org/2001/XMLSchema#string

Johann Meyer

http://www.w3.org/2001/XMLSchema#string

Julia Skokowa

http://www.w3.org/2001/XMLSchema#string

Karl Welte

http://www.w3.org/2001/XMLSchema#string

Kshama Gupta

http://www.w3.org/2001/XMLSchema#string

Maksim Klimiankou

http://www.w3.org/2001/XMLSchema#string

Malcolm A S Moore

http://www.w3.org/2001/XMLSchema#string

Olga Klimenkova

http://www.w3.org/2001/XMLSchema#string

P2860

STAT3 regulates Nemo-like kinase by mediating its interaction with IL-6-stimulated TGFbeta-activated kinase 1 for STAT3 Ser-727 phosphorylation

Mutations in the gene for the granulocyte colony-stimulating-factor receptor in patients with acute myeloid leukemia preceded by severe congenital neutropenia

LEF-1 is crucial for neutrophil granulocytopoiesis and its expression is severely reduced in congenital neutropenia

Role of the TAK1-NLK-STAT3 pathway in TGF-beta-mediated mesoderm induction

NARF, an nemo-like kinase (NLK)-associated ring finger protein regulates the ubiquitylation and degradation of T cell factor/lymphoid enhancer factor (TCF/LEF)

Regulation of lymphoid enhancer factor 1/T-cell factor by mitogen-activated protein kinase-related Nemo-like kinase-dependent phosphorylation in Wnt/beta-catenin signaling

Tyrosine kinase JAK1 is associated with the granulocyte-colony-stimulating factor receptor and both become tyrosine-phosphorylated after receptor activation

PIASy, a nuclear matrix-associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodies

ALY, a context-dependent coactivator of LEF-1 and AML-1, is required for TCRalpha enhancer function

TGFbeta3 signaling activates transcription of the LEF1 gene to induce epithelial mesenchymal transformation during mouse palate development

P304

2550-2561

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scholarly article

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10.1182/BLOOD-2012-09-456889

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English

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123

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2014-01-06T00:00:00Z

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259606803

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24394665

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P921

birth defect

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4968380

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Bortezomib inhibits STAT5-dependent degradation of LEF-1, inducing granulocytic differentiation in congenital neutropenia CD34(+) cells

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P2860

P2860

Bortezomib inhibits STAT5-dependent degradation of LEF-1, inducing granulocytic differentiation in congenital neutropenia CD34(+) cells

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P577

P5875

P698

P921

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P577

P5875

P698

P921

P932