Type 2 transglutaminase is involved in the autophagy-dependent clearance of ubiquitinated proteins.
about
Physiological, pathological, and structural implications of non-enzymatic protein-protein interactions of the multifunctional human transglutaminase 2Genomic variants reveal differential evolutionary constraints on human transglutaminases and point towards unrecognized significance of transglutaminase 2.Genetic deletion of transglutaminase 2 does not rescue the phenotypic deficits observed in R6/2 and zQ175 mouse models of Huntington's disease.Disruption of autophagy by the histone deacetylase inhibitor MGCD0103 and its therapeutic implication in B-cell chronic lymphocytic leukemia.Characterization of distinct sub-cellular location of transglutaminase type II: changes in intracellular distribution in physiological and pathological statesDysregulation of autophagy in human follicular lymphoma is independent of overexpression of BCL-2.Renal cell carcinoma escapes death by p53 depletion through transglutaminase 2-chaperoned autophagy.Polyamines: therapeutic perspectives in oxidative stress and inflammatory diseases.Molecular definitions of autophagy and related processes.Discovery of Therapeutic Approaches for Polyglutamine Diseases: A Summary of Recent Efforts.PINK1 phosphorylates transglutaminase 2 and blocks its proteasomal degradation.IP3 receptor mutations and brain diseases in human and rodents.Transglutaminase type 2: A multifunctional protein chaperone?Ribose 5-phosphate isomerase inhibits LC3 processing and basal autophagy.Transglutaminase 2 ablation leads to mitophagy impairment associated with a metabolic shift towards aerobic glycolysis.Discovery of a novel target for renal cell carcinoma: transglutaminase 2.Metabolic profiling of human CD4+ cells following treatment with methotrexate and anti-TNF-α infliximab.Inhibition of transglutaminase exacerbates polyglutamine-induced neurotoxicity by increasing the aggregation of mutant ataxin-3 in an SCA3 Drosophila model.Down-Regulation of Transglutaminase 2 Stimulates Redifferentiation of Dedifferentiated Chondrocytes through Enhancing Glucose Metabolism.Transglutaminase type 2 plays a key role in the pathogenesis of Mycobacterium tuberculosis infection.Non-alcoholic fatty liver disease severity is modulated by transglutaminase type 2.Polyamines and transglutaminases: future perspectives.Transglutaminase 2, a double face enzyme.Striatal Mutant Huntingtin Protein Levels Decline with Age in Homozygous Huntington's Disease Knock-In Mouse Models.
P2860
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P2860
Type 2 transglutaminase is involved in the autophagy-dependent clearance of ubiquitinated proteins.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Type 2 transglutaminase is inv ...... nce of ubiquitinated proteins.
@en
Type 2 transglutaminase is inv ...... nce of ubiquitinated proteins.
@nl
type
label
Type 2 transglutaminase is inv ...... nce of ubiquitinated proteins.
@en
Type 2 transglutaminase is inv ...... nce of ubiquitinated proteins.
@nl
prefLabel
Type 2 transglutaminase is inv ...... nce of ubiquitinated proteins.
@en
Type 2 transglutaminase is inv ...... nce of ubiquitinated proteins.
@nl
P2093
P2860
P50
P356
P1476
Type 2 transglutaminase is inv ...... nce of ubiquitinated proteins.
@en
P2093
G Di Giacomo
M G Farrace
M Piacentini
P2860
P2888
P304
P356
10.1038/CDD.2012.2
P577
2012-02-10T00:00:00Z
P5875
P6179
1050883544