Soluble human interleukin-6 receptor. Expression in insect cells, purification and characterization.
about
A functional role of the membrane-proximal extracellular domains of the signal transducer gp130 in heterodimerization with the leukemia inhibitory factor receptorThe MKK6/p38 mitogen-activated protein kinase pathway is capable of inducing SOCS3 gene expression and inhibits IL-6-induced transcriptionSoluble gp130 is the natural inhibitor of soluble interleukin-6 receptor transsignaling responsesIntracellular signaling prevents effective blockade of oncogenic gp130 mutants by neutralizing antibodies.Connective tissue growth factor reacts as an IL-6/STAT3-regulated hepatic negative acute phase proteinA primer on cytokines: sources, receptors, effects, and inducersInterferon Alpha Signalling and Its Relevance for the Upregulatory Effect of Transporter Proteins Associated with Antigen Processing (TAP) in Patients with Malignant Melanoma.Novel inhibitors for murine and human leukemia inhibitory factor based on fused soluble receptors.Oncostatin M induces RIG-I and MDA5 expression and enhances the double-stranded RNA response in fibroblasts.Characterization of the Interleukin (IL)-6 Inhibitor IL-6-RFP: fused receptor domains act as high affinity cytokine-binding proteins.Are STATS arginine-methylated?The role of the inhibitors of interleukin-6 signal transduction SHP2 and SOCS3 for desensitization of interleukin-6 signalling.Interleukin-6-induced proliferation of pre-B cells mediated by receptor complexes lacking the SHP2/SOCS3 recruitment sites revisited.Differential inhibition of IL-6-type cytokine-induced STAT activation by PMA.Constitutive internalization and association with adaptor protein-2 of the interleukin-6 signal transducer gp130.Activation of the signal transducer gp130 by interleukin-11 and interleukin-6 is mediated by similar molecular interactions.A complex of the soluble interleukin-6 receptor and interleukin-6 is internalized via the signal transducer gp130.Cytoplasmic STAT proteins associate prior to activation.Dominant-negative activity of the STAT3-Y705F mutant depends on the N-terminal domain.Dynamics of the gp130 cytokine complex: a model for assembly on the cellular membrane.A single amino acid substitution (Trp(666)-->Ala) in the interbox1/2 region of the interleukin-6 signal transducer gp130 abrogates binding of JAK1, and dominantly impairs signal transduction.Interleukin-6 acts in the fashion of a classical chemokine on monocytic cells by inducing integrin activation, cell adhesion, actin polymerization, chemotaxis, and transmigration.A panel of four cytokines predicts the prognosis of patients with malignant gliomas.
P2860
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P2860
Soluble human interleukin-6 receptor. Expression in insect cells, purification and characterization.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Soluble human interleukin-6 re ...... fication and characterization.
@en
Soluble human interleukin-6 re ...... fication and characterization.
@nl
type
label
Soluble human interleukin-6 re ...... fication and characterization.
@en
Soluble human interleukin-6 re ...... fication and characterization.
@nl
prefLabel
Soluble human interleukin-6 re ...... fication and characterization.
@en
Soluble human interleukin-6 re ...... fication and characterization.
@nl
P2093
P2860
P1433
P1476
Soluble human interleukin-6 re ...... fication and characterization.
@en
P2093
G Müller-Newen
J P Brakenhoff
J Schneider
P Kurschat
P2860
P304
P356
10.1111/J.1432-1033.1995.661_B.X
P407
P577
1995-12-01T00:00:00Z