CO binding kinetics of human cytochrome P450 3A4. Specific interaction of substrates with kinetically distinguishable conformers.
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The role of CYP2B6 in human xenobiotic metabolism.Two-dimensional NMR and all-atom molecular dynamics of cytochrome P450 CYP119 reveal hidden conformational substatesAllosteric phenomena in cytochrome P450-catalyzed monooxygenations.Dynamics and flexibility of human aromatase probed by FTIR and time resolved fluorescence spectroscopyCurrent Approaches for Investigating and Predicting Cytochrome P450 3A4-Ligand InteractionsEnergetics of heterotropic cooperativity between alpha-naphthoflavone and testosterone binding to CYP3A4Plasticity of cytochrome P450 isozyme expression in rat trigeminal ganglia neurons during inflammation.Current views on the fundamental mechanisms of cytochrome P450 allosterism.Coumarin Derivatives as Substrate Probes of Mammalian Cytochromes P450 2B4 and 2B6: Assessing the Importance of 7-Alkoxy Chain Length, Halogen Substitution, and Non-Active Site Mutations.The structural basis for homotropic and heterotropic cooperativity of midazolam metabolism by human cytochrome P450 3A4.Physical Studies of P450-P450 Interactions: Predicting Quaternary Structures of P450 Complexes in Membranes from Their X-ray Crystal Structures.Formation of P450 · P450 complexes and their effect on P450 functionSpectral resolution of a second binding site for Nile Red on cytochrome P4503A4.Effect of glutathione on homo- and heterotropic cooperativity in cytochrome P450 3A4.Studies on the toxicity of analogues of dapsone in-vitro using rat, human and heterologously expressed metabolizing systems.Sigmoidal kinetic model for two co-operative substrate-binding sites in a cytochrome P450 3A4 active site: an example of the metabolism of diazepam and its derivatives.Resolution of multiple substrate binding sites in cytochrome P450 3A4: the stoichiometry of the enzyme-substrate complexes probed by FRET and Job's titration.CYP261 enzymes from deep sea bacteria: a clue to conformational heterogeneity in cytochromes P450.Stochastic ensembles, conformationally adaptive teamwork, and enzymatic detoxification.Kinetics of CO ligation with nitric-oxide synthase by flash photolysis and stopped-flow spectrophotometry.7,8-benzoflavone binding to human cytochrome P450 3A4 reveals complex fluorescence quenching, suggesting binding at multiple protein sites.
P2860
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P2860
CO binding kinetics of human cytochrome P450 3A4. Specific interaction of substrates with kinetically distinguishable conformers.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
CO binding kinetics of human c ...... ly distinguishable conformers.
@en
CO binding kinetics of human c ...... ly distinguishable conformers.
@nl
type
label
CO binding kinetics of human c ...... ly distinguishable conformers.
@en
CO binding kinetics of human c ...... ly distinguishable conformers.
@nl
prefLabel
CO binding kinetics of human c ...... ly distinguishable conformers.
@en
CO binding kinetics of human c ...... ly distinguishable conformers.
@nl
P2093
P2860
P356
P1476
CO binding kinetics of human c ...... lly distinguishable conformers
@en
P2093
A Markowitz
F K Friedman
R C Robinson
P2860
P304
P356
10.1074/JBC.270.10.5014
P407
P577
1995-03-01T00:00:00Z