Simultaneous investigation of cardiac pyruvate dehydrogenase flux, Krebs cycle metabolism and pH, using hyperpolarized [1,2-(13)C2]pyruvate in vivo - Wikidata - awgldk - TriplyDB

Simultaneous investigation of cardiac pyruvate dehydrogenase flux, Krebs cycle metabolism and pH, using hyperpolarized [1,2-(13)C2]pyruvate in vivo

Simultaneous investigation of cardiac pyruvate dehydrogenase flux, Krebs cycle metabolism and pH, using hyperpolarized [1,2-(13)C2]pyruvate in vivo

http://www.wikidata.org/entity/Q42067957

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Potential Clinical Roles for Metabolic Imaging with Hyperpolarized [1-(13)C]Pyruvate Hyperpolarized magnetic resonance as a sensitive detector of metabolic function A review of responsive MRI contrast agents: 2005-2014 Detecting enzyme activities with exogenous MRI contrast agents Chemistry and biochemistry of 13C hyperpolarized magnetic resonance using dynamic nuclear polarization Mapping of intracellular pH in the in vivo rodent heart using hyperpolarized [1-13C]pyruvate.Joint spatial-spectral reconstruction and k-t spirals for accelerated 2D spatial/1D spectral imaging of 13C dynamics.Simultaneous imaging of 13C metabolism and 1H structure: technical considerations and potential applications.(13)C-labeled biochemical probes for the study of cancer metabolism with dynamic nuclear polarization-enhanced magnetic resonance imaging.Hyperpolarized (13)C magnetic resonance reveals early- and late-onset changes to in vivo pyruvate metabolism in the failing heart.Applications of NMR spectroscopy to systems biochemistry.Measuring mitochondrial metabolism in rat brain in vivo using MR Spectroscopy of hyperpolarized [2-¹³C]pyruvate.NMR of hyperpolarised probes.MRS: a noninvasive window into cardiac metabolism.T1 nuclear magnetic relaxation dispersion of hyperpolarized sodium and cesium hydrogencarbonate-13 C.Magnetic resonance imaging with hyperpolarized agents: methods and applications.The use of hyperpolarized carbon-13 magnetic resonance for molecular imaging.Using [1-(13) C]lactic acid for hyperpolarized (13) C MR cardiac studies.Simultaneous assessment of cardiac metabolism and perfusion using copolarized [1-13 C]pyruvate and 13 C-urea.Hyperpolarized [(13)C]ketobutyrate, a molecular analog of pyruvate with modified specificity for LDH isoforms.Concentric rings K-space trajectory for hyperpolarized (13)C MR spectroscopic imaging.Optimal variable flip angle schemes for dynamic acquisition of exchanging hyperpolarized substrates In vivo investigation of cardiac metabolism in the rat using MRS of hyperpolarized [1-13C] and [2-13C]pyruvate.A rapid method for direct detection of metabolic conversion and magnetization exchange with application to hyperpolarized substrates.Integrated, Step-Wise, Mass-Isotopomeric Flux Analysis of the TCA Cycle.Dynamic metabolic imaging of hyperpolarized [2-(13) C]pyruvate using spiral chemical shift imaging with alternating spectral band excitation.Reproducibility study for free-breathing measurements of pyruvate metabolism using hyperpolarized (13) C in the heart.Metabolic imaging of acute and chronic infarction in the perfused rat heart using hyperpolarised [1-13C]pyruvate.Probing the cardiac malate-aspartate shuttle non-invasively using hyperpolarized [1,2-13 C2 ]pyruvate.Imaging Regional Metabolic Changes in the Ischemic Rat Heart In Vivo Using Hyperpolarized [1-C]Pyruvate DNP Methods for Cardiac Metabolic Imaging with Hyperpolarized [1-13C]pyruvate Large Dose Injection in Pigs

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P2860

Simultaneous investigation of cardiac pyruvate dehydrogenase flux, Krebs cycle metabolism and pH, using hyperpolarized [1,2-(13)C2]pyruvate in vivo

http://www.wikidata.org/entity/Q42067957

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2011 nî lūn-bûn

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Simultaneous investigation of ...... d [1,2-(13)C2]pyruvate in vivo

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Simultaneous investigation of ...... d [1,2-(13)C2]pyruvate in vivo

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Simultaneous investigation of ...... d [1,2-(13)C2]pyruvate in vivo

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NMR in Biomedicine

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Albert P Chen

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Angus Z Lau

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Charles H Cunningham

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James Tropp

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Jennifer Barry

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Marie A Schroeder

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Ralph E Hurd

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Wilfred W Lam

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Yi-ping Gu

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P2860

Increase in signal-to-noise ratio of > 10,000 times in liquid-state NMR

Carbon dioxide transport and carbonic anhydrase in blood and muscle

The carbon dioxide hydration activity of carbonic anhydrase. I. Stop-flow kinetic studies on the native human isoenzymes B and C

Fast multiecho balanced SSFP metabolite mapping of (1)H and hyperpolarized (13)C compounds.

Measuring intracellular pH in the heart using hyperpolarized carbon dioxide and bicarbonate: a 13C and 31P magnetic resonance spectroscopy study

Haemodynamic effects of intracoronary pyruvate in patients with congestive heart failure: an open study.

Multi-compound polarization by DNP allows simultaneous assessment of multiple enzymatic activities in vivo

In vivo application of sub-second spiral chemical shift imaging (CSI) to hyperpolarized 13C metabolic imaging: comparison with phase-encoded CSI.

Detecting tumor response to treatment using hyperpolarized 13C magnetic resonance imaging and spectroscopy.

Real-time metabolic imaging.

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10.1002/NBM.1749

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2

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21774012

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4618301

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