γ-Secretase Modulators: Can We Combine Potency with Safety?
about
γ-Secretase inhibitors and modulators.Identification and Preclinical Pharmacology of the γ-Secretase Modulator BMS-869780.Therapeutic perspectives of drugs targeting Toll-like receptors based on immune physiopathology theory of Alzheimer's disease.Steroids as γ-secretase modulators.Development and mechanism of γ-secretase modulators for Alzheimer's disease.Complex relationships between substrate sequence and sensitivity to alterations in γ-secretase processivity induced by γ-secretase modulatorsNGP 555, a γ-Secretase Modulator, Lowers the Amyloid Biomarker, Aβ42, in Cerebrospinal Fluid while Preventing Alzheimer's Disease Cognitive Decline in Rodents.Design of Pyridopyrazine-1,6-dione γ-Secretase Modulators that Align Potency, MDR Efflux Ratio, and Metabolic Stability.Targeting development of incretin-producing cells increases insulin secretion.Structural and Chemical Biology of Presenilin Complexes.
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γ-Secretase Modulators: Can We Combine Potency with Safety?
description
2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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2012年学术文章
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name
γ-Secretase Modulators: Can We Combine Potency with Safety?
@en
γ-Secretase Modulators: Can We Combine Potency with Safety?
@nl
type
label
γ-Secretase Modulators: Can We Combine Potency with Safety?
@en
γ-Secretase Modulators: Can We Combine Potency with Safety?
@nl
prefLabel
γ-Secretase Modulators: Can We Combine Potency with Safety?
@en
γ-Secretase Modulators: Can We Combine Potency with Safety?
@nl
P2860
P356
P1476
γ-Secretase Modulators: Can We Combine Potency with Safety?
@en
P2093
Harrie J M Gijsen
Marc Mercken
P2860
P304
P356
10.1155/2012/295207
P577
2012-12-17T00:00:00Z