about
The CB2 receptor and its role as a regulator of inflammationAndrogen inactivation in human lung fibroblasts: variations in levels of 17 beta-hydroxysteroid dehydrogenase type 2 and 5 alpha-reductase activity compatible with androgen inactivationLeukotriene B₄ Metabolism and p70S6 Kinase 1 Inhibitors: PF-4708671 but Not LY2584702 Inhibits CYP4F3A and the ω-Oxidation of Leukotriene B₄ In Vitro and In CelluloCaffeic acid phenethyl ester and its amide analogue are potent inhibitors of leukotriene biosynthesis in human polymorphonuclear leukocytesRegulation of inflammation by cannabinoids, the endocannabinoids 2-arachidonoyl-glycerol and arachidonoyl-ethanolamide, and their metabolites.Crucial implication of protein kinase C (PKC)-delta, PKC-zeta, ERK-1/2, and p38 MAPK in migration of human asthmatic eosinophils.Treatment with a sphingosine analog after the inception of house dust mite-induced airway inflammation alleviates key features of experimental asthma.The Intracellular Localisation and Phosphorylation Profile of the Human 5-Lipoxygenase Δ13 Isoform Differs from That of Its Full Length CounterpartMetabolism of arachidonic acid to eicosanoids within the nucleus.Phosphorylation of serine 271 on 5-lipoxygenase and its role in nuclear export.Cellular analysis of the histamine H4 receptor in human myeloid cells.The Endocannabinoid Metabolite Prostaglandin E2 (PGE2)-Glycerol Inhibits Human Neutrophil Functions: Involvement of Its Hydrolysis into PGE2 and EP Receptors.Activation of TAK1 by Chemotactic and Growth Factors, and Its Impact on Human Neutrophil Signaling and Functional Responses.Plasma eicosanoid profiles determined by high-performance liquid chromatography coupled with tandem mass spectrometry in stimulated peripheral blood from healthy individuals and sickle cell anemia patients in treatment.Characterization of prostaglandin E2 generation through the cyclooxygenase (COX)-2 pathway in human neutrophils.Dormant 5-lipoxygenase in inflammatory macrophages is triggered by exogenous arachidonic acid.Histamine-induced inhibition of leukotriene biosynthesis in human neutrophils: involvement of the H2 receptor and cAMP.Effects of pyrrophenone, an inhibitor of group IVA phospholipase A2, on eicosanoid and PAF biosynthesis in human neutrophils.Phosphorylation by protein kinase a inhibits nuclear import of 5-lipoxygenase.Cyclic AMP-mediated inhibition of 5-lipoxygenase translocation and leukotriene biosynthesis in human neutrophils.Arachidonic acid activates phospholipase D in human neutrophils; essential role of endogenous leukotriene B4 and inhibition by adenosine A2A receptor engagement.CCL26/eotaxin-3 is more effective to induce the migration of eosinophils of asthmatics than CCL11/eotaxin-1 and CCL24/eotaxin-2.Reprogramming of a subpopulation of human blood neutrophils by prolonged exposure to cytokines.Arachidonic acid regulates the translocation of 5-lipoxygenase to the nuclear membranes in human neutrophils.Inhibition of platelet-activating factor biosynthesis by adenosine and histamine in human neutrophils: involvement of cPLA2alpha and reversal by lyso-PAF.NADPH oxidase deficiency results in reduced alveolar macrophage 5-lipoxygenase expression and decreased leukotriene synthesis.Differential regulation by leukotrienes and calcium of Fc gamma receptor-induced phagocytosis and Syk activation in dendritic cells versus macrophages.Comparison of eight 15-lipoxygenase (LO) inhibitors on the biosynthesis of 15-LO metabolites by human neutrophils and eosinophilsThe endocannabinoid 2-arachidonoyl-glycerol activates human neutrophils: critical role of its hydrolysis and de novo leukotriene B4 biosynthesisToll-like receptor ligands induce polymorphonuclear leukocyte migration: key roles for leukotriene B4 and platelet-activating factorPulmonary CD103 expression regulates airway inflammation in asthmaCorrelation between CCL26 production by human bronchial epithelial cells and airway eosinophils: Involvement in patients with severe eosinophilic asthmaMechanisms of human eosinophil migration induced by the combination of IL-5 and the endocannabinoid 2-arachidonoyl-glycerolHepatic NAPE-PLD Is a Key Regulator of Liver Lipid Metabolism
P50
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P50
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chercheur et professeur d'université
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hulumtues
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onderzoeker
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researcher and university professor
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հետազոտող
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Nicolas Flamand
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Nicolas Flamand
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Nicolas Flamand
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Nicolas Flamand
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Nicolas Flamand
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Nicolas Flamand
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Nicolas Flamand
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Nicolas Flamand
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Nicolas Flamand
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Nicolas Flamand
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Nicolas Flamand
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Nicolas Flamand
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Nicolas Flamand
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Nicolas Flamand
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Nicolas Flamand
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Nicolas Flamand
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Nicolas Flamand
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Nicolas Flamand
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