Cheliensisin A inhibits EGF-induced cell transformation with stabilization of p53 protein via a hydrogen peroxide/Chk1-dependent axis.
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Isorhapontigenin (ISO) inhibited cell transformation by inducing G0/G1 phase arrest via increasing MKP-1 mRNA Stability.Loss of p27 upregulates MnSOD in a STAT3-dependent manner, disrupts intracellular redox activity and enhances cell migration.PHLPP2 Downregulation Contributes to Lung Carcinogenesis Following B[a]P/B[a]PDE ExposureCheliensisin A (Chel A) induces apoptosis in human bladder cancer cells by promoting PHLPP2 protein degradation.Hydrogen peroxide/ATR-Chk2 activation mediates p53 protein stabilization and anti-cancer activity of cheliensisin A in human cancer cells.Crucial role of c-Jun phosphorylation at Ser63/73 mediated by PHLPP protein degradation in the cheliensisin a inhibition of cell transformation.
P2860
Cheliensisin A inhibits EGF-induced cell transformation with stabilization of p53 protein via a hydrogen peroxide/Chk1-dependent axis.
description
2013 nî lūn-bûn
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
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2013年论文
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2013年论文
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name
Cheliensisin A inhibits EGF-in ...... peroxide/Chk1-dependent axis.
@en
Cheliensisin A inhibits EGF-in ...... peroxide/Chk1-dependent axis.
@nl
type
label
Cheliensisin A inhibits EGF-in ...... peroxide/Chk1-dependent axis.
@en
Cheliensisin A inhibits EGF-in ...... peroxide/Chk1-dependent axis.
@nl
prefLabel
Cheliensisin A inhibits EGF-in ...... peroxide/Chk1-dependent axis.
@en
Cheliensisin A inhibits EGF-in ...... peroxide/Chk1-dependent axis.
@nl
P2093
P2860
P1476
Cheliensisin A inhibits EGF-in ...... peroxide/Chk1-dependent axis.
@en
P2093
Dongyun Zhang
Guangxun Gao
Jingjie Zhang
Jingxia Li
Liang Chen
Qinshi Zhao
Yonghui Yu
P2860
P304
P356
10.1158/1940-6207.CAPR-13-0097
P577
2013-07-12T00:00:00Z