Validation of the in vivo assessment of pyruvate dehydrogenase activity using hyperpolarised 13C MRS.
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Hyperpolarized magnetic resonance as a sensitive detector of metabolic functionHow the signal-to-noise ratio influences hyperpolarized 13C dynamic MRS data fitting and parameter estimation.Propionate stimulates pyruvate oxidation in the presence of acetateMultisite Kinetic Modeling of (13)C Metabolic MR Using [1-(13)C]Pyruvate.Hyperpolarized magnetic resonance: a novel technique for the in vivo assessment of cardiovascular disease.In vivo assessment of cardiac metabolism and function in the abdominal aortic banding model of compensated cardiac hypertrophyImpaired in vivo mitochondrial Krebs cycle activity after myocardial infarction assessed using hyperpolarized magnetic resonance spectroscopy.Immunocapture and microplate-based activity and quantity measurement of pyruvate dehydrogenase in human peripheral blood mononuclear cells.Fumarate is cardioprotective via activation of the Nrf2 antioxidant pathway.Application of hyperpolarized [1-¹³C]lactate for the in vivo investigation of cardiac metabolism.Robust and high resolution hyperpolarized metabolic imaging of the rat heart at 7 T with 3D spectral-spatial EPIThe cycling of acetyl-coenzyme A through acetylcarnitine buffers cardiac substrate supply: a hyperpolarized 13C magnetic resonance study.Role of pyruvate dehydrogenase inhibition in the development of hypertrophy in the hyperthyroid rat heart: a combined magnetic resonance imaging and hyperpolarized magnetic resonance spectroscopy study.Volumetric spiral chemical shift imaging of hyperpolarized [2-(13) c]pyruvate in a rat c6 glioma model.Hyperpolarized 13C NMR observation of lactate kinetics in skeletal muscle.Hyperpolarized (13)C magnetic resonance reveals early- and late-onset changes to in vivo pyruvate metabolism in the failing heart.In vivo mouse cardiac hyperpolarized magnetic resonance spectroscopy.Thiamine as an adjunctive therapy in cardiac surgery: a randomized, double-blind, placebo-controlled, phase II trial.Modeling non-linear kinetics of hyperpolarized [1-(13)C] pyruvate in the crystalloid-perfused rat heart.Simultaneous in vivo assessment of cardiac and hepatic metabolism in the diabetic rat using hyperpolarized MRS.The von Hippel-Lindau Chuvash mutation in mice alters cardiac substrate and high-energy phosphate metabolism.Imaging oxygen metabolism with hyperpolarized magnetic resonance: a novel approach for the examination of cardiac and renal functionMyocardial substrate metabolism in obesity.Recent advances in metabolic imaging.MRS: a noninvasive window into cardiac metabolism.Mini-Review on Cardiac Metabolic Imaging: current imaging modalities and future perspectives.Assessment of real-time myocardial uptake and enzymatic conversion of hyperpolarized [1-¹³C]pyruvate in pigs using slice selective magnetic resonance spectroscopy.Cardiovascular Applications of Hyperpolarized MRI.Determining the in vivo regulation of cardiac pyruvate dehydrogenase based on label flux from hyperpolarised [1-13C]pyruvate.In vivo investigation of cardiac metabolism in the rat using MRS of hyperpolarized [1-13C] and [2-13C]pyruvate.Increasing Pyruvate Dehydrogenase Flux as a Treatment for Diabetic Cardiomyopathy: A Combined 13C Hyperpolarized Magnetic Resonance and Echocardiography Study.In vivo alterations in cardiac metabolism and function in the spontaneously hypertensive rat heart.Hyperpolarized butyrate: a metabolic probe of short chain fatty acid metabolism in the heart.Enhancing the [13C]bicarbonate signal in cardiac hyperpolarized [1-13C]pyruvate MRS studies by infusion of glucose, insulin and potassium.Reproducibility study for free-breathing measurements of pyruvate metabolism using hyperpolarized (13) C in the heart.Metabolic imaging of acute and chronic infarction in the perfused rat heart using hyperpolarised [1-13C]pyruvate.Hyperpolarized 13 C magnetic resonance evaluation of renal ischemia reperfusion injury in a murine model.Increasing cardiac pyruvate dehydrogenase flux during chronic hypoxia improves acute hypoxic tolerance.Acute renal metabolic effect of metformin assessed with hyperpolarised MRI in rats.Hyperpolarized [1,(13)C]pyruvate in lysed human erythrocytes: effects of co-substrate supply on reaction time courses.
P2860
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P2860
Validation of the in vivo assessment of pyruvate dehydrogenase activity using hyperpolarised 13C MRS.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Validation of the in vivo asse ...... using hyperpolarised 13C MRS.
@en
Validation of the in vivo asse ...... using hyperpolarised 13C MRS.
@nl
type
label
Validation of the in vivo asse ...... using hyperpolarised 13C MRS.
@en
Validation of the in vivo asse ...... using hyperpolarised 13C MRS.
@nl
prefLabel
Validation of the in vivo asse ...... using hyperpolarised 13C MRS.
@en
Validation of the in vivo asse ...... using hyperpolarised 13C MRS.
@nl
P2093
P2860
P356
P1433
P1476
Validation of the in vivo asse ...... using hyperpolarised 13C MRS.
@en
P2093
Emma E Carter
George K Radda
Helen J Atherton
Kieran Clarke
Lisa C Heather
Lowri E Cochlin
Marie A Schroeder
Nicola R Sibson
Simon Nagel
P2860
P304
P356
10.1002/NBM.1573
P577
2010-08-26T00:00:00Z