Combination of lenalidomide with vitamin D3 induces apoptosis in mantle cell lymphoma via demethylation of BIK.

about

A simple flow cytometry-based barcode for routine authentication of multiple myeloma and mantle cell lymphoma cell lines.

P2860

Q50958153-58BDF393-BFE2-4878-BE6C-4120540CE8B2

P2860

Combination of lenalidomide with vitamin D3 induces apoptosis in mantle cell lymphoma via demethylation of BIK.

Item

http://www.wikidata.org/entity/Q42111039

description

2014 nî lūn-bûn

@nan

2014年の論文

@ja

2014年論文

@yue

2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

2014年论文

@zh

2014年论文

@zh-cn

name

Combination of lenalidomide wi ...... homa via demethylation of BIK.

@en

Combination of lenalidomide wi ...... homa via demethylation of BIK.

@nl

type

Item

label

Combination of lenalidomide wi ...... homa via demethylation of BIK.

@en

Combination of lenalidomide wi ...... homa via demethylation of BIK.

@nl

prefLabel

Combination of lenalidomide wi ...... homa via demethylation of BIK.

@en

Combination of lenalidomide wi ...... homa via demethylation of BIK.

@nl

P1476

Combination of lenalidomide wi ...... homa via demethylation of BIK.

@en

P2093

C Brosseau

http://www.w3.org/2001/XMLSchema#string

C Dousset

http://www.w3.org/2001/XMLSchema#string

C Pellat-Deceunynck

http://www.w3.org/2001/XMLSchema#string

C Touzeau

http://www.w3.org/2001/XMLSchema#string

P Moreau

http://www.w3.org/2001/XMLSchema#string

S Le Gouill

http://www.w3.org/2001/XMLSchema#string

S Maïga

http://www.w3.org/2001/XMLSchema#string

P2860

BH3 domains other than Bim and Bid can directly activate Bax/Bak

Cereblon is a direct protein target for immunomodulatory and antiproliferative activities of lenalidomide and pomalidomide

Induction of cell death by the BH3-only Bcl-2 homolog Nbk/Bik is mediated by an entirely Bax-dependent mitochondrial pathway

BH-3-only BIK functions at the endoplasmic reticulum to stimulate cytochrome c release from mitochondria

Single-agent lenalidomide in patients with mantle-cell lymphoma who relapsed or progressed after or were refractory to bortezomib: phase II MCL-001 (EMERGE) study.

Loss of the tissue-specific proapoptotic BH3-only protein Nbk/Bik is a unifying feature of renal cell carcinoma.

Mcl-1 determines the Bax dependency of Nbk/Bik-induced apoptosis.

Lenalidomide monotherapy in relapsed or refractory aggressive non-Hodgkin's lymphoma.

An international phase II trial of single-agent lenalidomide for relapsed or refractory aggressive B-cell non-Hodgkin's lymphoma.

Lenalidomide in combination with rituximab for patients with relapsed or refractory mantle-cell lymphoma: a phase 1/2 clinical trial.

P304

e1389

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/CDDIS.2014.346

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Martine Amiot

P577

2014-08-28T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

265133607

http://www.w3.org/2001/XMLSchema#string

P698

25165875

http://www.w3.org/2001/XMLSchema#string

P932

4454319

http://www.w3.org/2001/XMLSchema#string

Combination of lenalidomide with vitamin D3 induces apoptosis in mantle cell lymphoma via demethylation of BIK.

about

P2860

P2860

Combination of lenalidomide with vitamin D3 induces apoptosis in mantle cell lymphoma via demethylation of BIK.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P478

P50

P577

P5875

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P478

P50

P577

P5875

P698

P932