3-Aminopropanal, formed during cerebral ischaemia, is a potent lysosomotropic neurotoxin
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Plant ALDH10 Family: IDENTIFYING CRITICAL RESIDUES FOR SUBSTRATE SPECIFICITY AND TRAPPING A THIOHEMIACETAL INTERMEDIATEPurification, crystallization and preliminary crystallographic study of a recombinant plant aminoaldehyde dehydrogenase from Pisum sativum.Simulation-based cheminformatic analysis of organelle-targeted molecules: lysosomotropic monobasic amines.Cationic poly(amidoamine) dendrimer induces lysosomal apoptotic pathway at therapeutically relevant concentrations.The subcellular distribution of small molecules: a meta-analysis.Mechanisms of amine accumulation in, and egress from, lysosomes.Aldehyde sources, metabolism, molecular toxicity mechanisms, and possible effects on human health.Lysosomal cysteine cathepsins: signaling pathways in apoptosis.Lysosomes in iron metabolism, ageing and apoptosis.The subcellular distribution of small molecules: from pharmacokinetics to synthetic biologyLysosomal membrane permeabilization as a key player in brain ischemic cell death: a "lysosomocentric" hypothesis for ischemic brain damage.Cytotoxicity of 1,4-diamino-2-butanone, a putrescine analogue, to RKO cells: mechanism and redox imbalance.Lysosomal membrane permeabilization causes oxidative stress and ferritin induction in macrophages.Polyamine catabolism is enhanced after traumatic brain injury.Autophagy fails to prevent glucose deprivation/glucose reintroduction-induced neuronal death due to calpain-mediated lysosomal dysfunction in cortical neurons.Protein kinase C-δ isoform mediates lysosome labilization in DNA damage-induced apoptosisOxidative stress stimulates autophagic flux during ischemia/reperfusionSpermine synthase deficiency causes lysosomal dysfunction and oxidative stress in models of Snyder-Robinson syndrome.3-Aminopropanal is a lysosomotropic aldehyde that causes oxidative stress and apoptosis by rupturing lysosomes.Astrocyte-Dependent Vulnerability to Excitotoxicity in Spermine Oxidase-Overexpressing Mouse.
P2860
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P2860
3-Aminopropanal, formed during cerebral ischaemia, is a potent lysosomotropic neurotoxin
description
2003 nî lūn-bûn
@nan
2003年の論文
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2003年論文
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2003年論文
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2003年論文
@zh-hk
2003年論文
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2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
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2003年论文
@zh-cn
name
3-Aminopropanal, formed during cerebral ischaemia, is a potent lysosomotropic neurotoxin
@en
3-Aminopropanal, formed during cerebral ischaemia, is a potent lysosomotropic neurotoxin
@nl
type
label
3-Aminopropanal, formed during cerebral ischaemia, is a potent lysosomotropic neurotoxin
@en
3-Aminopropanal, formed during cerebral ischaemia, is a potent lysosomotropic neurotoxin
@nl
prefLabel
3-Aminopropanal, formed during cerebral ischaemia, is a potent lysosomotropic neurotoxin
@en
3-Aminopropanal, formed during cerebral ischaemia, is a potent lysosomotropic neurotoxin
@nl
P2093
P2860
P356
P1433
P1476
3-Aminopropanal, formed during cerebral ischaemia, is a potent lysosomotropic neurotoxin
@en
P2093
John W Eaton
Svetlana Ivanova
Ulf T Brunk
Xi-Ming Yuan
P2860
P304
P356
10.1042/BJ20021520
P407
P577
2003-04-01T00:00:00Z