Fractal heterogeneity in minimal matrix models of scars modulates stiff-niche stem-cell responses via nuclear exit of a mechanorepressor.
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Progress in material design for biomedical applicationsDefinition of fractal topography to essential understanding of scale-invarianceMatrix Mechanosensing: From Scaling Concepts in 'Omics Data to Mechanisms in the Nucleus, Regeneration, and Cancer.A mathematical model of mechanotransduction reveals how mechanical memory regulates mesenchymal stem cell fate decisions.β3 integrin-mediated spreading induced by matrix-bound BMP-2 controls Smad signaling in a stiffness-independent mannerNuclear lamins in cancerMechanotransduction in cancer.The soft mechanical signature of glial scars in the central nervous systemCell signaling regulation by protein phosphorylation: a multivariate, heterogeneous, and context-dependent process.Causes and consequences of nuclear envelope alterations in tumour progression.Cellular adaptation to biomechanical stress across length scales in tissue homeostasis and disease.Mimicking biological functionality with polymers for biomedical applications.Mechanosensing by the nucleus: From pathways to scaling relationships.A Pathway to Personalizing Therapy for Metastases Using Liver-on-a-Chip Platforms.Mechanosensing of matrix by stem cells: From matrix heterogeneity, contractility, and the nucleus in pore-migration to cardiogenesis and muscle stem cells in vivo.Cross-linked matrix rigidity and soluble retinoids synergize in nuclear lamina regulation of stem cell differentiationN-terminal specific conjugation of extracellular matrix proteins to 2-pyridinecarboxaldehyde functionalized polyacrylamide hydrogelsEctogenic tension promotes fibrogenesis of mesenchymal stem cells through microRNA-21.Signs of stress on soft surfaces : A commentary on: Cui, Y., F.M. Hameed, B. Yang, K. Lee, C.Q. Pan, S. Park, and M. Sheetz. 2015. Cyclic stretching of soft substrates induces spreading and growth. Nat Commun. 6:6333.Three-dimensional organotypic matrices from alternative collagen sources as pre-clinical models for cell biology.Mechanosensing and fibrosis.Stem Cell Differentiation is Regulated by Extracellular Matrix Mechanics.Coordinated increase of nuclear tension and lamin-A with matrix stiffness outcompetes lamin-B receptor that favors soft tissue phenotypes.MicroRNA-21 preserves the fibrotic mechanical memory of mesenchymal stem cells.Persistence-Driven Durotaxis: Generic, Directed Motility in Rigidity Gradients.Inflammatory cytokine IL-8/CXCL8 promotes tumour escape from hepatocyte-induced dormancy.Photo-responsive hydrogels with photoswitchable mechanical properties allow time-resolved analysis of cellular responses to matrix stiffening.DNA Damage Follows Repair Factor Depletion and Portends Genome Variation in Cancer Cells after Pore Migration.Nanofiber technology: its transformative role in nanomedicine.NKX2.5 is expressed in papillary thyroid carcinomas and regulates differentiation in thyroid cells.Hydrogel as a bioactive material to regulate stem cell fate.Progerin phosphorylation in interphase is lower and less mechanosensitive than lamin-A,C in iPS-derived mesenchymal stem cells.An immortalised mesenchymal stem cell line maintains mechano-responsive behaviour and can be used as a reporter of substrate stiffness.Mussel-inspired post-heparinization of a stretchable hollow hydrogel tube and its potential application as an artificial blood vessel
P2860
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P2860
Fractal heterogeneity in minimal matrix models of scars modulates stiff-niche stem-cell responses via nuclear exit of a mechanorepressor.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Fractal heterogeneity in minim ...... ar exit of a mechanorepressor.
@en
Fractal heterogeneity in minim ...... ar exit of a mechanorepressor.
@nl
type
label
Fractal heterogeneity in minim ...... ar exit of a mechanorepressor.
@en
Fractal heterogeneity in minim ...... ar exit of a mechanorepressor.
@nl
prefLabel
Fractal heterogeneity in minim ...... ar exit of a mechanorepressor.
@en
Fractal heterogeneity in minim ...... ar exit of a mechanorepressor.
@nl
P2093
P2860
P50
P356
P1433
P1476
Fractal heterogeneity in minim ...... ar exit of a mechanorepressor.
@en
P2093
Amnon Buxboim
Dennis E Discher
Matthew Raab
Sangkyun Cho
P2860
P2888
P304
P356
10.1038/NMAT4350
P407
P577
2015-07-13T00:00:00Z
P6179
1038126056