Arginine modifications by methylglyoxal: discovery in a recombinant monoclonal antibody and contribution to acidic species.
about
In vitro and in vivo modifications of recombinant and human IgG antibodiesArg354 in the catalytic centre of bovine liver catalase is protected from methylglyoxal-mediated glycation.Mildly acidic conditions eliminate deamidation artifact during proteolysis: digestion with endoprotease Glu-C at pH 4.5.Neo-Epitopes Generated on Hydroxyl Radical Modified GlycatedIgG Have Role in Immunopathology of Diabetes Type 2Comparison of Protein N-Homocysteinylation in Rat Plasma under Elevated Homocysteine Using a Specific Chemical Labeling Method.Tailoring recombinant protein quality by rational media design.Mass spectrometric determination of early and advanced glycation in biology.Impact of cell culture on recombinant monoclonal antibody product heterogeneity.Glycation of antibodies: Modification, methods and potential effects on biological functions.Detection and quantitation of succinimide in intact protein via hydrazine trapping and chemical derivatization.Discovery of a chemical modification by citric acid in a recombinant monoclonal antibody.Characterization of acidic and basic variants of IgG1 therapeutic monoclonal antibodies based on non-denaturing IEF fractionation.Glycation of Lys-16 and Arg-5 in amyloid-β and the presence of Cu2+ play a major role in the oxidative stress mechanism of Alzheimer's disease.Analytical comparability study of recombinant monoclonal antibody therapeutics.
P2860
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P2860
Arginine modifications by methylglyoxal: discovery in a recombinant monoclonal antibody and contribution to acidic species.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Arginine modifications by meth ...... ontribution to acidic species.
@en
Arginine modifications by meth ...... ontribution to acidic species.
@nl
type
label
Arginine modifications by meth ...... ontribution to acidic species.
@en
Arginine modifications by meth ...... ontribution to acidic species.
@nl
prefLabel
Arginine modifications by meth ...... ontribution to acidic species.
@en
Arginine modifications by meth ...... ontribution to acidic species.
@nl
P2093
P2860
P356
P1433
P1476
Arginine modifications by meth ...... ontribution to acidic species.
@en
P2093
Chris Chumsae
Czeslaw H Radziejewski
Hongcheng Liu
Kathreen Gifford
Zhaohui Sunny Zhou
P2860
P304
11401-11409
P356
10.1021/AC402384Y
P407
P577
2013-11-18T00:00:00Z