Positive-feedback loops as a flexible biological module.
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Synthetic biology: lessons from engineering yeast MAPK signalling pathwaysEpigenetic and conventional regulation is distributed among activators of FLO11 allowing tuning of population-level heterogeneity in its expressionStructure and properties of transcriptional networks driving selenite stress response in yeastsGenetically engineered transvestites reveal novel mating genes in budding yeast.Rational design of memory in eukaryotic cellsPrediction by promoter logic in bacterial quorum sensingImproved use of a public good selects for the evolution of undifferentiated multicellularityStochastic expression and epigenetic memory at the yeast HO promoterTranscriptional autoregulatory loops are highly conserved in vertebrate evolution.Classification of genes and putative biomarker identification using distribution metrics on expression profilesEukaryotic systems broaden the scope of synthetic biology.Nitrile-inducible gene expression in mycobacteria.Dynamically reshaping signaling networks to program cell fate via genetic controllersMaking cellular memories.A novel phosphatase cascade regulates differentiation in Trypanosoma brucei via a glycosomal signaling pathway.Misfolded proteins impose a dosage-dependent fitness cost and trigger a cytosolic unfolded protein response in yeast.Permanent genetic memory with >1-byte capacityUsing engineered scaffold interactions to reshape MAP kinase pathway signaling dynamics.Genetic variation and the fate of beneficial mutations in asexual populations.Stochastic signalling rewires the interaction map of a multiple feedback network during yeast evolution.Self-regulation in a minimal model of chemical self-replication.Endogenous molecular network reveals two mechanisms of heterogeneity within gastric cancerA fungicide-responsive kinase as a tool for synthetic cell fate regulation.T-bet and GATA3 orchestrate Th1 and Th2 differentiation through lineage-specific targeting of distal regulatory elements.Regulation of cell-to-cell variability in divergent gene expression.Membrane localization of scaffold proteins promotes graded signaling in the yeast MAP kinase cascade.Small-scale copy number variation and large-scale changes in gene expression.Dynamic analysis of MAPK signaling using a high-throughput microfluidic single-cell imaging platform.A constitutively active GPCR governs morphogenic transitions in Cryptococcus neoformansMolecular recordings by directed CRISPR spacer acquisition.Engineering dynamical control of cell fate switching using synthetic phospho-regulons.Quantitative implementation of the endogenous molecular-cellular network hypothesis in hepatocellular carcinoma.Strategies for protein synthetic biology.The regulation of filamentous growth in yeast.Impact of Zygosity on Bimodal Phenotype Distributions.Rewiring yeast osmostress signalling through the MAPK network reveals essential and non-essential roles of Hog1 in osmoadaptation.The application of powerful promoters to enhance gene expression in industrial microorganisms.Noise can induce bimodality in positive transcriptional feedback loops without bistability.A critical quantity for noise attenuation in feedback systems.Tuning the activation threshold of a kinase network by nested feedback loops
P2860
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P2860
Positive-feedback loops as a flexible biological module.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Positive-feedback loops as a flexible biological module.
@en
Positive-feedback loops as a flexible biological module.
@nl
type
label
Positive-feedback loops as a flexible biological module.
@en
Positive-feedback loops as a flexible biological module.
@nl
prefLabel
Positive-feedback loops as a flexible biological module.
@en
Positive-feedback loops as a flexible biological module.
@nl
P2860
P1433
P1476
Positive-feedback loops as a flexible biological module.
@en
P2093
Andrew W Murray
Nicholas T Ingolia
P2860
P304
P356
10.1016/J.CUB.2007.03.016
P407
P577
2007-03-29T00:00:00Z