about
Adenovirus-mediated knockout of a conditional glucokinase gene in isolated pancreatic islets reveals an essential role for proximal metabolic coupling events in glucose-stimulated insulin secretionDual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinaseCell-specific roles of glucokinase in glucose homeostasis.Hepatocyte-specific mutation establishes retinoid X receptor alpha as a heterodimeric integrator of multiple physiological processes in the liver.Phosphoenolpyruvate carboxykinase is necessary for the integration of hepatic energy metabolism.O-GlcNAcylation increases ChREBP protein content and transcriptional activity in the liverThe lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humansLRH-1-dependent glucose sensing determines intermediary metabolism in liver.Hepatic gene regulation by glucose and polyunsaturated fatty acids: a role for ChREBP.ChREBP, a transcriptional regulator of glucose and lipid metabolism.Cloning and characterization of the mouse glucokinase gene locus and identification of distal liver-specific DNase I hypersensitive sites.Matrix metalloproteinase 11 protects from diabesity and promotes metabolic switch.Role of ChREBP in hepatic steatosis and insulin resistance.The transcription factor COUP-TFII is negatively regulated by insulin and glucose via Foxo1- and ChREBP-controlled pathwaysNovel Grb14-Mediated Cross Talk between Insulin and p62/Nrf2 Pathways Regulates Liver Lipogenesis and Selective Insulin Resistance.Carbohydrate responsive element binding protein and lipid homeostasis.The role of the lipogenic pathway in the development of hepatic steatosis.Cross-regulation of hepatic glucose metabolism via ChREBP and nuclear receptors.Novel insights into ChREBP regulation and function.Liver-specific inhibition of ChREBP improves hepatic steatosis and insulin resistance in ob/ob mice.O-GlcNAcylation Links ChREBP and FXR to Glucose-SensingIntegration of ChREBP-Mediated Glucose Sensing into Whole Body Metabolism.Insights into the role of hepatocyte PPARα activity in response to fasting.Sweet Sixteenth for ChREBP: Established Roles and Future Goals.Growth factor receptor binding protein 14 inhibition triggers insulin-induced mouse hepatocyte proliferation and is associated with hepatocellular carcinoma.Hepatokines: unlocking the multi-organ network in metabolic diseases.Farnesoid X receptor inhibits the transcriptional activity of carbohydrate response element binding protein in human hepatocytes.MondoA/ChREBP: The usual suspects of transcriptional glucose sensing; Implication in pathophysiology.Brain glucagon-like peptide-1 increases insulin secretion and muscle insulin resistance to favor hepatic glycogen storage.Dietary oleic acid regulates hepatic lipogenesis through a liver X receptor-dependent signalingCorrigendum: Matrix metalloproteinase 11 protects from diabesity and promotes metabolic switch.Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD.Glucose transporter expression in rat mammary glandChREBP, but not LXRs, is required for the induction of glucose-regulated genes in mouse liver.Essential fatty acids deficiency promotes lipogenic gene expression and hepatic steatosis through the liver X receptor.Evidence for a transient inhibitory effect of insulin on GLUT2 expression in the liver: studies in vivo and in vitro.Polyunsaturated fatty acids suppress glycolytic and lipogenic genes through the inhibition of ChREBP nuclear protein translocation.Little caves ameliorate hepatic insulin signaling. Focus on "caveolin gene transfer improves glucose metabolism in diabetic mice".Glucokinase gene locus transgenic mice are resistant to the development of obesity-induced type 2 diabetes.Analysis of the Cre-mediated recombination driven by rat insulin promoter in embryonic and adult mouse pancreas.
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description
hulumtuese
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researcher
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հետազոտող
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name
Catherine Postic
@ast
Catherine Postic
@en
Catherine Postic
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Catherine Postic
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Catherine Postic
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type
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Catherine Postic
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Catherine Postic
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Catherine Postic
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Catherine Postic
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Catherine Postic
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prefLabel
Catherine Postic
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Catherine Postic
@en
Catherine Postic
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Catherine Postic
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Catherine Postic
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P214
P1053
P-2271-2017
P106
P108
P21
P213
0000 0003 5700 7118
P214
P31
P3829
P496
0000-0002-1875-6960
P735
P7859
viaf-194003045