Several phenylalanine-glycine motives in the nucleoporin Nup214 are essential for binding of the nuclear export receptor CRM1.
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Structural Basis of Targeting the Exportin CRM1 in CancerNucleoporin FG domains facilitate mRNP remodeling at the cytoplasmic face of the nuclear pore complexChromatin-prebound Crm1 recruits Nup98-HoxA9 fusion to induce aberrant expression of Hox cluster genes.The selective permeability barrier in the nuclear pore complexLeukemia-Associated Nup214 Fusion Proteins Disturb the XPO1-Mediated Nuclear-Cytoplasmic Transport Pathway and Thereby the NF-κB Signaling Pathway.The Oncogenic Fusion Proteins SET-Nup214 and Sequestosome-1 (SQSTM1)-Nup214 Form Dynamic Nuclear Bodies and Differentially Affect Nuclear Protein and Poly(A)+ RNA Export.Nuclear egress of TDP-43 and FUS occurs independently of Exportin-1/CRM1.Exportin Crm1 is repurposed as a docking protein to generate microtubule organizing centers at the nuclear pore.Nucleoporin Gene Fusions and Hematopoietic Malignancies
P2860
Q26781513-4F930B34-C340-441D-BC74-633D6375E07DQ34016584-D48111C6-3CC1-4955-9B0D-C1633E4374F2Q36479682-EB4662C2-0DB1-4CFA-9A0D-822C4788F515Q38965634-4A760EE5-00BF-4911-8B8C-4A6ABA90D684Q40699389-7BAF210A-8FB3-4032-816E-466981EF0CFFQ42725755-0A57FD95-B0AD-42BB-A022-B3ADB4306D2FQ55038139-016B1A90-9489-4988-B521-49991D9089E6Q55412292-E114C5F1-F411-4E1E-A709-06554C3D5484Q59072645-EFC89525-C4C0-4892-A12F-F80FA26CBE9F
P2860
Several phenylalanine-glycine motives in the nucleoporin Nup214 are essential for binding of the nuclear export receptor CRM1.
description
2012 nî lūn-bûn
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2012年の論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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2012年论文
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2012年论文
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2012年论文
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name
Several phenylalanine-glycine ...... nuclear export receptor CRM1.
@en
Several phenylalanine-glycine ...... nuclear export receptor CRM1.
@nl
type
label
Several phenylalanine-glycine ...... nuclear export receptor CRM1.
@en
Several phenylalanine-glycine ...... nuclear export receptor CRM1.
@nl
prefLabel
Several phenylalanine-glycine ...... nuclear export receptor CRM1.
@en
Several phenylalanine-glycine ...... nuclear export receptor CRM1.
@nl
P2860
P356
P1476
Several phenylalanine-glycine ...... e nuclear export receptor CRM1
@en
P2093
Christiane Spillner
Stephanie Roloff
P2860
P304
P356
10.1074/JBC.M112.433243
P407
P577
2012-12-21T00:00:00Z