about
Advancing Clostridia to Clinical Trial: Past Lessons and Recent ProgressSBRC-Nottingham: sustainable routes to platform chemicals from C1 waste gasesSporulation studies in Clostridium difficileImportant role of class I heat shock genes hrcA and dnaK in the heat shock response and the response to pH and NaCl stress of group I Clostridium botulinum strain ATCC 3502Development and implementation of rapid metabolic engineering tools for chemical and fuel production in Geobacillus thermoglucosidasius NCIMB 11955Development of an inducible transposon system for efficient random mutagenesis in Clostridium acetobutylicumInsights into CO2 Fixation Pathway of Clostridium autoethanogenum by Targeted MutagenesisProduction of a functional cell wall-anchored minicellulosome by recombinant Clostridium acetobutylicum ATCC 824Secretion and assembly of functional mini-cellulosomes from synthetic chromosomal operons in Clostridium acetobutylicum ATCC 824Disruption of the acetate kinase (ack) gene of Clostridium acetobutylicum results in delayed acetate productionFunctional Intestinal Bile Acid 7α-Dehydroxylation by Clostridium scindens Associated with Protection from Clostridium difficile Infection in a Gnotobiotic Mouse ModelComplete Genome Sequence of Geobacillus thermoglucosidasius NCIMB 11955, the Progenitor of a Bioethanol Production StrainThe binary toxin CDT enhances Clostridium difficile virulence by suppressing protective colonic eosinophilia.Inflammasome activation contributes to interleukin-23 production in response to Clostridium difficile.The analysis of para-cresol production and tolerance in Clostridium difficile 027 and 012 strains.Genome sequencing shows that European isolates of Francisella tularensis subspecies tularensis are almost identical to US laboratory strain Schu S4.A mariner-based transposon system for in vivo random mutagenesis of Clostridium difficile.Array comparative hybridisation reveals a high degree of similarity between UK and European clinical isolates of hypervirulent Clostridium difficile.Development of Clostridium difficile R20291ΔPaLoc model strains and in vitro methodologies reveals CdtR is required for the production of CDT to cytotoxic levels.Spores of Clostridium engineered for clinical efficacy and safety cause regression and cure of tumors in vivoReconsidering the sporulation characteristics of hypervirulent Clostridium difficile BI/NAP1/027.The role of toxin A and toxin B in Clostridium difficile infection.Spores of Clostridium difficile clinical isolates display a diverse germination response to bile saltsClostridia in cancer therapy.The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome.Regulation of cel genes of C. cellulolyticum: identification of GlyR2, a transcriptional regulator regulating cel5D gene expression.Expanding the repertoire of gene tools for precise manipulation of the Clostridium difficile genome: allelic exchange using pyrE alleles.Two-component signal transduction system CBO0787/CBO0786 represses transcription from botulinum neurotoxin promoters in Clostridium botulinum ATCC 3502.Clostridium difficile modulates host innate immunity via toxin-independent and dependent mechanism(s).The role of flagella in Clostridium difficile pathogenesis: comparison between a non-epidemic and an epidemic strainThe flagellin FliC of Clostridium difficile is responsible for pleiotropic gene regulation during in vivo infection.A universal mariner transposon system for forward genetic studies in the genus ClostridiumGenome Sequence of the Solvent-Producing Clostridium beijerinckii Strain 59B, Isolated from Staffordshire Garden SoilComplete Genome Sequence of the Nitrogen-Fixing and Solvent-Producing Clostridium pasteurianum DSM 525Closed Genome Sequence of Clostridium pasteurianum ATCC 6013.Complete Genome Sequence of the Nonpathogenic Soil-Dwelling Bacterium Clostridium sporogenes Strain NCIMB 10696.The SOS Response Master Regulator LexA Is Associated with Sporulation, Motility and Biofilm Formation in Clostridium difficile.Riboswitch (T-box)-mediated control of tRNA-dependent amidation in Clostridium acetobutylicum rationalizes gene and pathway redundancy for asparagine and asparaginyl-trnaasn synthesis.Microbial solvent formation revisited by comparative genome analysisWhole genome sequence and manual annotation of Clostridium autoethanogenum, an industrially relevant bacterium
P50
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P50
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Nigel P Minton
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Nigel P Minton
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Nigel P Minton
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Nigel P Minton
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Nigel P Minton
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Nigel P Minton
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Nigel P Minton
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P214
P244
P106
P21
P213
0000 0000 3053 1401
P214
P244
P31
P496
0000-0002-9277-1261
P735
P7859
lccn-n88268209