BeAtMuSiC: Prediction of changes in protein-protein binding affinity on mutations.
about
Combining structural modeling with ensemble machine learning to accurately predict protein fold stability and binding affinity effects upon mutationPredicting Binding Free Energy Change Caused by Point Mutations with Knowledge-Modified MM/PBSA MethodmCSM-lig: quantifying the effects of mutations on protein-small molecule affinity in genetic disease and emergence of drug resistanceRecombinant deamidated mutants of Erwinia chrysanthemi L-asparaginase have similar or increased activity compared to wild-type enzyme.A dock and coalesce mechanism driven by hydrophobic interactions governs Cdc42 binding with its effector protein ACKInferring the microscopic surface energy of protein-protein interfaces from mutation data.Determining effects of non-synonymous SNPs on protein-protein interactions using supervised and semi-supervised learning.Computational and experimental approaches to reveal the effects of single nucleotide polymorphisms with respect to disease diagnosticsCooperation of B cell lineages in induction of HIV-1-broadly neutralizing antibodies.Catalytically relevant electrostatic interactions of cytochrome P450c17 (CYP17A1) and cytochrome b5.Integrating water exclusion theory into β contacts to predict binding free energy changes and binding hot spotsPredicting the Impact of Missense Mutations on Protein-Protein Binding Affinity.Better prediction of functional effects for sequence variants.Predicting the Effect of Mutations on Protein-Protein Binding Interactions through Structure-Based Interface Profiles.Co-Occurring Atomic Contacts for the Characterization of Protein Binding Hot SpotsBalancing Protein Stability and Activity in Cancer: A New Approach for Identifying Driver Mutations Affecting CBL Ubiquitin Ligase ActivationBindProfX: Assessing Mutation-Induced Binding Affinity Change by Protein Interface Profiles with Pseudo-Counts.Systematic substitutions at BLIP position 50 result in changes in binding specificity for class A β-lactamases.PROXiMATE: A database of mutant protein-protein complex thermodynamics and kinetics.Conservative and compensatory evolution in oxidative phosphorylation complexes of angiosperms with highly divergent rates of mitochondrial genome evolution.SAAMBE: Webserver to Predict the Charge of Binding Free Energy Caused by Amino Acids Mutations.Modeling and fitting protein-protein complexes to predict change of binding energyMutaBind estimates and interprets the effects of sequence variants on protein-protein interactions.Allosteric Dynamic Control of Binding.Integration of structural dynamics and molecular evolution via protein interaction networks: a new era in genomic medicine.Computing disease-linked SOD1 mutations: deciphering protein stability and patient-phenotype relations.Tools for Predicting the Functional Impact of Nonsynonymous Genetic Variation.Annotating Mutational Effects on Proteins and Protein Interactions: Designing Novel and Revisiting Existing Protocols.Functional variomics and network perturbation: connecting genotype to phenotype in cancer.Combating mutations in genetic disease and drug resistance: understanding molecular mechanisms to guide drug design.Cofactors-loaded quaternary structure of lysine-specific demethylase 5C (KDM5C) protein: Computational model.Optogenetic Modulation of Intracellular Signalling and Transcription: Focus on Neuronal Plasticity.Exploring the interplay between experimental methods and the performance of predictors of binding affinity change upon mutations in protein complexes.On human disease-causing amino acid variants: statistical study of sequence and structural patterns.ELASPIC web-server: proteome-wide structure-based prediction of mutation effects on protein stability and binding affinity.Revealing the Effects of Missense Mutations Causing Snyder-Robinson Syndrome on the Stability and Dimerization of Spermine Synthase.In Silico Prediction of the Effects of Mutations in the Human Mevalonate Kinase Gene: Towards a Predictive Framework for Mevalonate Kinase Deficiency.Engineering Specificity from Broad to Narrow: Design of a β-Lactamase Inhibitory Protein (BLIP) Variant That Exclusively Binds and Detects KPC β-Lactamase.BALL-SNP: combining genetic and structural information to identify candidate non-synonymous single nucleotide polymorphisms.ABS-Scan: In silico alanine scanning mutagenesis for binding site residues in protein-ligand complex.
P2860
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P2860
BeAtMuSiC: Prediction of changes in protein-protein binding affinity on mutations.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
BeAtMuSiC: Prediction of changes in protein-protein binding affinity on mutations.
@en
BeAtMuSiC: Prediction of changes in protein-protein binding affinity on mutations.
@nl
type
label
BeAtMuSiC: Prediction of changes in protein-protein binding affinity on mutations.
@en
BeAtMuSiC: Prediction of changes in protein-protein binding affinity on mutations.
@nl
prefLabel
BeAtMuSiC: Prediction of changes in protein-protein binding affinity on mutations.
@en
BeAtMuSiC: Prediction of changes in protein-protein binding affinity on mutations.
@nl
P2860
P356
P1476
BeAtMuSiC: Prediction of changes in protein-protein binding affinity on mutations
@en
P2093
Jean Marc Kwasigroch
Marianne Rooman
P2860
P304
P356
10.1093/NAR/GKT450
P433
Web Server issue
P577
2013-05-30T00:00:00Z