Src, PKCalpha, and PKCdelta are required for alphavbeta3 integrin-mediated metastatic melanoma invasion. - Wikidata - awgldk - TriplyDB

Src, PKCalpha, and PKCdelta are required for alphavbeta3 integrin-mediated metastatic melanoma invasion.

Src, PKCalpha, and PKCdelta are required for alphavbeta3 integrin-mediated metastatic melanoma invasion.

http://www.wikidata.org/entity/Q42141281

about

An engineered knottin peptide labeled with 18F for PET imaging of integrin expression.Short hairpin RNA-mediated fibronectin knockdown delays tumor growth in a mouse glioma model.Collagen fragments inhibit hyaluronan synthesis in skin fibroblasts in response to ultraviolet B (UVB): new insights into mechanisms of matrix remodeling.Expression and functional role of CRIPTO-1 in cutaneous melanoma.ANGPTL4-αvβ3 interaction counteracts hypoxia-induced vascular permeability by modulating Src signalling downstream of vascular endothelial growth factor receptor 2.Protein kinase Cα (PKCα) regulates p53 localization and melanoma cell survival downstream of integrin αv in three-dimensional collagen and in vivo Rictor/mTORC2 regulates blood-testis barrier dynamics via its effects on gap junction communications and actin filament network.LKB1/STK11 inactivation leads to expansion of a prometastatic tumor subpopulation in melanoma PKCδ regulates integrin αVβ3 expression and transformed growth of K-ras dependent lung cancer cells.Specifying protein kinase C functions in melanoma.Matched rabbit monoclonal antibodies against αv-series integrins reveal a novel αvβ3-LIBS epitope, and permit routine staining of archival paraffin samples of human tumors.Abolished adherence alters signaling pathways in phorbol ester-induced human U937 cells.Multifunctional roles of PKCδ: Opportunities for targeted therapy in human disease Systems Chemo-Biology and Transcriptomic Meta-Analysis Reveal the Molecular Roles of Bioactive Lipids in Cardiomyocyte Differentiation.Assessment of the tumourigenic and metastatic properties of SK-MEL28 melanoma cells surviving electrochemotherapy with bleomycin.OSU-2S/Sorafenib Synergistic Antitumor Combination against Hepatocellular Carcinoma: The Role of PKCδ/p53.Protein kinase C activation stimulates mesenchymal stem cell adhesion through activation of focal adhesion kinase.Reactive oxygen species-mediated PKC and integrin signaling promotes tumor progression of human hepatoma HepG2.Protein Kinase C (PKC) Isozymes and Cancer

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P2860

Src, PKCalpha, and PKCdelta are required for alphavbeta3 integrin-mediated metastatic melanoma invasion.

http://www.wikidata.org/entity/Q42141281

description

2009 nî lūn-bûn

@nan

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

2009年论文

@zh

2009年论文

@zh-cn

name

Src, PKCalpha, and PKCdelta ar ...... metastatic melanoma invasion.

@en

Src, PKCalpha, and PKCdelta ar ...... metastatic melanoma invasion.

@nl

type

label

Src, PKCalpha, and PKCdelta ar ...... metastatic melanoma invasion.

@en

Src, PKCalpha, and PKCdelta ar ...... metastatic melanoma invasion.

@nl

prefLabel

Src, PKCalpha, and PKCdelta ar ...... metastatic melanoma invasion.

@en

Src, PKCalpha, and PKCdelta ar ...... metastatic melanoma invasion.

@nl

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Cell Communication and Signaling

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Src, PKCalpha, and PKCdelta ar ...... metastatic melanoma invasion.

@en

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Andrew J Putnam

http://www.w3.org/2001/XMLSchema#string

Cindy K Miranti

http://www.w3.org/2001/XMLSchema#string

Eric M Freiter

http://www.w3.org/2001/XMLSchema#string

Heather M Bill

http://www.w3.org/2001/XMLSchema#string

Veronique V Schulz

http://www.w3.org/2001/XMLSchema#string

P2860

Src kinase activation by direct interaction with the integrin beta cytoplasmic domain

RhoC is dispensable for embryogenesis and tumor initiation but essential for metastasis.

Cell migration: integrating signals from front to back

Genomic analysis of metastasis reveals an essential role for RhoC

Rho and Rac take center stage

The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

Src family kinases are required for integrin but not PDGFR signal transduction.

The adaptor protein Tks5/Fish is required for podosome formation and function, and for the protease-driven invasion of cancer cells.

Protein kinase C regulates alpha v beta 5-dependent cytoskeletal associations and focal adhesion kinase phosphorylation.

Talin depletion reveals independence of initial cell spreading from integrin activation and traction.

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10

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scholarly article

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10.1186/1478-811X-7-10

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7

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2009-04-28T00:00:00Z

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1034223270

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19400942

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2683837

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