Dual neuroprotective pathways of a pro-electrophilic compound via HSF-1-activated heat-shock proteins and Nrf2-activated phase 2 antioxidant response enzymes
about
Endogenous Generation and Signaling Actions of Omega-3 Fatty Acid Electrophilic DerivativesThe Interplay Between Peroxiredoxin-2 and Nuclear Factor-Erythroid 2 Is Important in Limiting Oxidative Mediated Dysfunction in β-Thalassemic ErythropoiesisRegulation of the mammalian heat shock factor 1.Expression of xCT and activity of system xc(-) are regulated by NRF2 in human breast cancer cells in response to oxidative stress.Protection from cyanide-induced brain injury by the Nrf2 transcriptional activator carnosic acidRedox pioneer: Professor Stuart A. Lipton.Endoplasmic reticulum stress: its role in disease and novel prospects for therapy.The Role of Sulfhydryl Reactivity of Small Molecules for the Activation of the KEAP1/NRF2 Pathway and the Heat Shock ResponseNrf2/ARE-mediated antioxidant actions of pro-electrophilic drugs.A retrospective review of the progress in amyotrophic lateral sclerosis drug discovery over the last decade and a look at the latest strategies.Nrf2 and HSF-1 Pathway Activation via Hydroquinone-Based Proelectrophilic Small Molecules is Regulated by Electrochemical Oxidation Potential.Zonarol, a sesquiterpene from the brown algae Dictyopteris undulata, provides neuroprotection by activating the Nrf2/ARE pathway.Krebs Cycle Intermediates Protective against Oxidative Stress by Modulating the Level of Reactive Oxygen Species in Neuronal HT22 Cells.Histone deacetylases inhibition by SAHA/Vorinostat normalizes the glioma microenvironment via xCT equilibration.MEF2D haploinsufficiency downregulates the NRF2 pathway and renders photoreceptors susceptible to light-induced oxidative stress.Recent advances in understanding NRF2 as a druggable target: development of pro-electrophilic and non-covalent NRF2 activators to overcome systemic side effects of electrophilic drugs like dimethyl fumarate.
P2860
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P2860
Dual neuroprotective pathways of a pro-electrophilic compound via HSF-1-activated heat-shock proteins and Nrf2-activated phase 2 antioxidant response enzymes
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Dual neuroprotective pathways ...... 2 antioxidant response enzymes
@en
Dual neuroprotective pathways ...... 2 antioxidant response enzymes
@nl
type
label
Dual neuroprotective pathways ...... 2 antioxidant response enzymes
@en
Dual neuroprotective pathways ...... 2 antioxidant response enzymes
@nl
prefLabel
Dual neuroprotective pathways ...... 2 antioxidant response enzymes
@en
Dual neuroprotective pathways ...... 2 antioxidant response enzymes
@nl
P2093
P2860
P1476
Dual neuroprotective pathways ...... 2 antioxidant response enzymes
@en
P2093
Carmen R Sunico
Chihiro Kosegawa
Gregory P Roth
Hideharu Taira
Jennifer K Hoffman
Masaaki Seki
Mika Yanagitai
Mutsumi Senzaki
Scott R McKercher
Stuart A Lipton
P2860
P304
P356
10.1111/J.1471-4159.2011.07449.X
P407
P577
2011-09-21T00:00:00Z