Hedgehog inhibition prolongs survival in a genetically engineered mouse model of pancreatic cancer.
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Deciphering the role of hedgehog signaling in pancreatic cancerHedgehog Signaling in Pancreatic Fibrosis and CancerGenomic alterations in pancreatic cancer and their relevance to therapyGEMMs as preclinical models for testing pancreatic cancer therapiesMolecular Targeted Intervention for Pancreatic CancerSonic Hedgehog in pancreatic cancer: from bench to bedside, then back to the benchGenetically engineered mouse models of pancreatic adenocarcinomaPersonalized medicine in sporadic pancreatic cancer without homologous recombination-deficiency: are we any closer?Repression of the miR-143/145 cluster by oncogenic Ras initiates a tumor-promoting feed-forward pathwayPancreatic cancers require autophagy for tumor growthOverexpression of smoothened activates the sonic hedgehog signaling pathway in pancreatic cancer-associated fibroblasts.Fms related tyrosine kinase 1 (Flt1) functions as an oncogene and regulates glioblastoma cell metastasis by regulating sonic hedgehog signaling.KRAS, Hedgehog, Wnt and the twisted developmental biology of pancreatic ductal adenocarcinoma.Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinomaStromal response to Hedgehog signaling restrains pancreatic cancer progression.Pancreatic cancer and its stroma: a conspiracy theoryCyclin-dependent kinase inhibitor Dinaciclib (SCH727965) inhibits pancreatic cancer growth and progression in murine xenograft modelsSynthetic triterpenoids prolong survival in a transgenic mouse model of pancreatic cancer.Genome-wide screening reveals an EMT molecular network mediated by Sonic hedgehog-Gli1 signaling in pancreatic cancer cells.Smarter drugs emerging in pancreatic cancer therapy.Genome-wide characterization of pancreatic adenocarcinoma patients using next generation sequencing.Molecular characteristics of pancreatic ductal adenocarcinomaSonic hedgehog signaling pathway supports cancer cell growth during cancer radiotherapy.Chemoradiation therapy using cyclopamine-loaded liquid-lipid nanoparticles and lutetium-177-labeled core-crosslinked polymeric micelles.Ectopic overexpression of Sonic Hedgehog (Shh) induces stromal expansion and metaplasia in the adult murine pancreas.Deploying mouse models of pancreatic cancer for chemoprevention studiesRandomized Phase Ib/II Study of Gemcitabine Plus Placebo or Vismodegib, a Hedgehog Pathway Inhibitor, in Patients With Metastatic Pancreatic Cancer.Genes targeted by the Hedgehog-signaling pathway can be regulated by Estrogen related receptor βInhibition of sonic hedgehog pathway and pluripotency maintaining factors regulate human pancreatic cancer stem cell characteristicsOncogenic transcription factors: cornerstones of inflammation-linked pancreatic carcinogenesisHypomethylating therapy in an aggressive stroma-rich model of pancreatic carcinoma.Nicotinamide N-methyltransferase: a potential biomarker for worse prognosis in gastric carcinoma.Understanding and targeting cancer stem cells: therapeutic implications and challenges.Inhibition of the hedgehog pathway targets the tumor-associated stroma in pancreatic cancer.Hypoxia triggers hedgehog-mediated tumor-stromal interactions in pancreatic cancer.Cyclopamine-loaded core-cross-linked polymeric micelles enhance radiation response in pancreatic cancer and pancreatic stellate cells.In vitro models of pancreatic cancer for translational oncology research.Challenges and advances in mouse modeling for human pancreatic tumorigenesis and metastasisNicotinamide N-methyltransferase enhances resistance to 5-fluorouracil in colorectal cancer cells through inhibition of the ASK1-p38 MAPK pathway.Molecular biology of pancreatic ductal adenocarcinoma progression: aberrant activation of developmental pathways.
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P2860
Hedgehog inhibition prolongs survival in a genetically engineered mouse model of pancreatic cancer.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Hedgehog inhibition prolongs s ...... se model of pancreatic cancer.
@en
Hedgehog inhibition prolongs s ...... se model of pancreatic cancer.
@nl
type
label
Hedgehog inhibition prolongs s ...... se model of pancreatic cancer.
@en
Hedgehog inhibition prolongs s ...... se model of pancreatic cancer.
@nl
prefLabel
Hedgehog inhibition prolongs s ...... se model of pancreatic cancer.
@en
Hedgehog inhibition prolongs s ...... se model of pancreatic cancer.
@nl
P2093
P2860
P356
P1433
P1476
Hedgehog inhibition prolongs s ...... se model of pancreatic cancer.
@en
P2093
C Karikari
G Feldmann
M M Ouellette
M Mullendore
N Bardeesy
P2860
P304
P356
10.1136/GUT.2007.148189
P407
P577
2008-05-30T00:00:00Z