Efflux pumps of Mycobacterium tuberculosis play a significant role in antituberculosis activity of potential drug candidates.
about
Novel adjunctive therapies for the treatment of tuberculosisLipoamide Channel-Binding Sulfonamides Selectively Inhibit Mycobacterial Lipoamide DehydrogenaseFirst-in-Class Inhibitors of Sulfur Metabolism with Bactericidal Activity against Non-Replicating M. tuberculosisEfflux pump gene expression in multidrug-resistant Mycobacterium tuberculosis clinical isolatesConfinement-Induced Drug-Tolerance in Mycobacteria Mediated by an Efflux MechanismMicrobial efflux systems and inhibitors: approaches to drug discovery and the challenge of clinical implementationNew Insights in to the Intrinsic and Acquired Drug Resistance Mechanisms in MycobacteriaTuberculosis: Drug discovery goes au naturel.Eliminating the heart from the curcumin molecule: monocarbonyl curcumin mimics (MACs).The efflux pump inhibitor timcodar improves the potency of antimycobacterial agents.Tetrandrine reverses drug resistance in isoniazid and ethambutol dual drug-resistant Mycobacterium tuberculosis clinical isolates.In vitro and in vivo Evaluation of Synergism between Anti-Tubercular Spectinamides and Non-Classical Tuberculosis AntibioticsFunctional characterization of the Mycobacterium abscessus genome coupled with condition specific transcriptomics reveals conserved molecular strategies for host adaptation and persistenceAlkaloid extracts from Combretum zeyheri inhibit the growth of Mycobacterium smegmatis.Mechanisms of Resistance to Aminoglycoside Antibiotics: Overview and PerspectivesAntimicrobial efflux pumps and Mycobacterium tuberculosis drug tolerance: evolutionary considerations.Molecular epidemiology and mechanisms of tigecycline resistance in clinical isolates of Acinetobacter baumannii from a Chinese university hospital.Spectinamides: a new class of semisynthetic antituberculosis agents that overcome native drug effluxSynergistic efficacy of Bisbenzimidazole and Carbonyl Cyanide 3-Chlorophenylhydrazone combination against MDR bacterial strains.Energy metabolism and drug efflux in Mycobacterium tuberculosisUnderstanding efflux in Gram-negative bacteria: opportunities for drug discovery.Inhibitors of mycobacterial efflux pumps as potential boosters for anti-tubercular drugs.Efflux pump inhibitors: targeting mycobacterial efflux systems to enhance TB therapy.Structure-Activity Relationships of Spectinamide Antituberculosis Agents: A Dissection of Ribosomal Inhibition and Native Efflux Avoidance Contributions.The expression of ABC efflux pump, Rv1217c-Rv1218c, and its association with multidrug resistance of Mycobacterium tuberculosis in China.Involvement of efflux pumps in the resistance to peptidoglycan synthesis inhibitors in Mycobacterium tuberculosisMycobacterium tuberculosis Major Facilitator Superfamily Transporters.Potentiation of antibacterial activity of the MB-1 siderophore-monobactam conjugate using an efflux pump inhibitorSuperoxide-mediated protection of Escherichia coli from antimicrobials.Role of the Mmr efflux pump in drug resistance in Mycobacterium tuberculosis.Hit Generation in TB Drug Discovery: From Genome to Granuloma.Multifaceted remodeling by vitamin C boosts sensitivity of Mycobacterium tuberculosis subpopulations to combination treatment by anti-tubercular drugs.Accelerating early anti-tuberculosis drug discovery by creating mycobacterial indicator strains that predict mode of action.Efflux Pumps in Mycobacteria: Antimicrobial Resistance, Physiological Functions, and Role in PathogenicityMeasuring Efflux and Permeability in Mycobacteria
P2860
Q26829957-37E3F37C-4D86-44C9-8D51-EAAE4BCDC1D3Q27680644-AD86BC6F-7062-4B5F-B413-1E776C995656Q28354028-12541681-9999-4040-BA4A-737EF8018B04Q28543543-D7667013-D65F-4383-BA43-B50F93BC71CCQ28547410-89B6ED75-195E-410E-991A-7A9ACE50EAB4Q33355620-74162999-524A-41C3-8779-68D4A33A2EF2Q33600161-BF698CF7-345B-4540-849E-B3940F8DE3BAQ34074707-95783659-7F19-4087-8873-CAF5CA259979Q35034180-36657AD9-3E7C-4B9B-AA14-B304D2F9F7B8Q35076888-68AF8E8A-7D9E-4D53-A333-B0B69448D8D3Q35562635-C606F39F-3AC9-4F1B-A653-162986C1D430Q36056408-DD32C96B-7589-4CE4-B58C-51B38E360E57Q36096266-333E52C5-6150-4145-89DB-94B489F11C52Q36287713-EFDC0873-7729-4288-AB22-9265E6DF39F4Q36575916-BEA6CC6F-8FC8-41E7-A307-7E0878B235A7Q37385024-20B29C86-4BC2-4611-860A-8FA32CEA57CCQ37544374-A6C3FE74-B50C-4A8E-AE04-5A1378281331Q37679508-2B9074B9-CC8D-4220-8E57-D638FE0DCC71Q37707919-D98F461A-4580-43A4-B28E-675B7BDAC2ABQ37712986-B5405D05-5748-480C-80B8-845F4A50853CQ38011247-7C646F8F-3914-422A-8C05-9B697AD5ECB5Q38056146-9AD068C0-391F-4DCD-A542-5665CEB20632Q38608754-5750DD72-6634-449A-B26C-D60C2B164EEDQ39024197-0384A205-571C-4621-B38A-D3B096F72898Q39521856-0E30C0CF-176E-40A6-9B0A-12F5BFFAFE51Q39765849-6A89026A-94F6-4173-A127-6DA661B134BEQ40075126-3CFAC349-DC42-49DB-AAF3-3916F640A7A7Q42089886-B05BE775-AF4C-48EB-B23C-72724263D20DQ42116431-7C364159-B6FB-4D68-8E96-8B78B72A5500Q42128862-05E1734E-1EDE-4D6A-AEB7-872D34D2129CQ47702665-1040102E-D681-489B-B5CE-FF0E0F850C41Q48508433-F8496633-6205-4EC7-8CBE-3794515406B0Q52584716-40B40B6F-705E-4000-8375-4F1768FB7672Q57656351-DA9388F3-5486-4C35-8F54-CB991E592F91Q57656378-41FE9134-BF82-44AF-B2F7-6810FD14ED91
P2860
Efflux pumps of Mycobacterium tuberculosis play a significant role in antituberculosis activity of potential drug candidates.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Efflux pumps of Mycobacterium ...... of potential drug candidates.
@en
Efflux pumps of Mycobacterium ...... of potential drug candidates.
@nl
type
label
Efflux pumps of Mycobacterium ...... of potential drug candidates.
@en
Efflux pumps of Mycobacterium ...... of potential drug candidates.
@nl
prefLabel
Efflux pumps of Mycobacterium ...... of potential drug candidates.
@en
Efflux pumps of Mycobacterium ...... of potential drug candidates.
@nl
P2093
P2860
P356
P1476
Efflux pumps of Mycobacterium ...... of potential drug candidates.
@en
P2093
Anju V Nair
Meenakshi Balganesh
Neela Dinesh
Sanjana Kuruppath
Sreevalli Sharma
Umender Sharma
P2860
P304
P356
10.1128/AAC.06003-11
P407
P577
2012-02-06T00:00:00Z