Activating hotspot L205R mutation in PRKACA and adrenal Cushing's syndrome.
about
Mouse Models Recapitulating Human Adrenocortical Tumors: What Is Lacking?Intracellular Molecular Differences in Aldosterone- Compared to Cortisol-Secreting Adrenal Cortical AdenomasDNAJB1-PRKACA is specific for fibrolamellar carcinoma.Alterations of Phosphodiesterases in Adrenocortical TumorsFibrolamellar Hepatocellular Carcinoma: Mechanistic Distinction From Adult Hepatocellular CarcinomaInsights from exome sequencing for endocrine disordersThe roles of the RIIβ linker and N-terminal cyclic nucleotide-binding domain in determining the unique structures of the type IIβ protein kinase A: a small angle x-ray and neutron scattering study.Uncovering Aberrant Mutant PKA Function with Flow Cytometric FRETIdentification of stage-specific biomarkers in lung adenocarcinoma based on RNA-seq data.Protein kinase A catalytic subunit isoform PRKACA; History, function and physiologyPRKACA mediates resistance to HER2-targeted therapy in breast cancer cells and restores anti-apoptotic signaling.Genomic analysis of fibrolamellar hepatocellular carcinoma.Rapid intra-adrenal feedback regulation of glucocorticoid synthesis.Structural insights into mis-regulation of protein kinase A in human tumors.Pediatric adrenocortical tumors: what they can tell us on adrenal development and comparison with adult adrenal tumors.Neomorphic effects of recurrent somatic mutations in Yin Yang 1 in insulin-producing adenomas.Germline PRKACA amplification causes variable phenotypes that may depend on the extent of the genomic defect: molecular mechanisms and clinical presentations.Two-pore domain potassium channels in the adrenal cortex.PRKACA: the catalytic subunit of protein kinase A and adrenocortical tumors.In-vivo detection of binary PKA network interactions upon activation of endogenous GPCRsDevelopment of adrenal cortex zonation.Protein kinase A defects and cortisol-producing adrenal tumorsSteroidogenic Acute Regulatory Protein Overexpression Correlates with Protein Kinase A Activation in Adrenocortical Adenoma.CLASP2 is involved in the EMT and early progression after transurethral resection of the bladder tumor.Regulation of the adrenocortical stem cell niche: implications for diseaseThe pleiotropic role of exchange protein directly activated by cAMP 1 (EPAC1) in cancer: implications for therapeutic intervention.Genomic analyses reveal FAM84B and the NOTCH pathway are associated with the progression of esophageal squamous cell carcinoma.Activating mutations in CTNNB1 in aldosterone producing adenomas.Adrenal Cushing's syndrome in pregnancy: Clinical and molecular characterisation of a case.Arrestin-biased AT1R agonism induces acute catecholamine secretion through TRPC3 coupling.Genetic mutations in sporadic pituitary adenomas--what to screen for?Clinicopathological correlates of adrenal Cushing's syndrome.Cushing's syndrome: from physiological principles to diagnosis and clinical care.Genetics of adrenal diseases in 2014: Genetics improves understanding of adrenocortical tumours.Novel Insights into the Genetics and Pathophysiology of Adrenocortical Tumors.Importance of gene dosage in controlling dendritic arbor formation during development.5th International ACC Symposium: The New Genetics of Benign Adrenocortical Neoplasia: Hyperplasias, Adenomas, and Their Implications for Progression into Cancer.A genetic and molecular update on adrenocortical causes of Cushing syndrome.Genetics of adrenocortical tumours.Lithium and an EPAC-specific inhibitor ESI-09 synergistically suppress pancreatic cancer cell proliferation and survival.
P2860
Q26740687-DA0D6E21-89C8-4A43-8D17-379F93B652E5Q26742189-711B24D0-5445-4307-9E9E-AEA105E74644Q27853135-7FB50FA5-181E-47E9-919E-26ACE7FE6557Q28066278-4208C62F-9DDF-45FD-A1CE-1E91CEB4DF5DQ28072292-D99D61E0-80A4-4F74-A079-8022EC2E2C56Q28088772-ECE0D271-47F3-47E6-9039-CBD9A75DB801Q30365578-0C6D1839-ED9C-43D9-BAD9-8A2A41195680Q30387436-C2EE1FDA-E2D9-49BA-9744-07A868E32F57Q30929193-33EBE144-E925-4220-8DF7-85C1540905AAQ34505964-51C2B2C6-0DE3-4277-B475-61B9A4607563Q34664078-DDF84630-9466-454A-88FB-985840AA4A5BQ34673400-1FCC4018-79C4-44E4-AAE5-629615BB8F3FQ34775266-54BDF35E-D420-4651-B0EF-DE5AE20634A9Q35062811-F0AC5E7D-E0BA-42E8-BF1C-225E9724CA0EQ35094565-0161CAE1-6E45-40DD-86C8-1BA871648A12Q35279380-C9F78AA6-2C31-4FCA-B5F0-0080DF7A3065Q35595823-4FB5DC61-2566-4DB2-87AF-3B8501AF8546Q35597757-A9AF65C5-DA1D-4F43-A3DF-9D9B2647B453Q35627125-926D0976-E639-4992-A337-38677FC9B3E1Q35769802-8291DF80-8E87-4649-80CA-5BCFB3908134Q35800278-EA918E03-5D48-4DB1-9DE2-82F7BD4C1755Q36030218-C676A3DC-F5D6-4F08-A170-0B0418E49674Q36126238-0A7D8B95-8303-4B5E-AB07-9BD84984F08BQ36272100-DD7B9A26-AD63-4B7B-AA22-5B6F24FF5BF8Q36288064-F37D59E3-1965-4173-9ECB-5501A0D1BEC9Q36398745-88F5921C-B016-40E6-B459-BDB46CFD8DC8Q36454484-7DCA7FB6-936A-4B52-B296-E0B59DBDFD1AQ36506804-A1300ECC-6BCC-4988-AC9A-3CF1E524D653Q37107360-6A77F9BF-8A76-4F76-9D0B-FA4846B3E02BQ37642774-3782154D-B59B-4555-8148-CFCA8FE09290Q38263242-0DA4AECC-EF66-4F58-B133-54A6C9A783ACQ38271545-40C46C6D-2827-410F-AD04-ECB00B081D98Q38284048-B3B467F0-AAD0-47EC-9C69-B34C071D63D5Q38289453-560AF35D-AC02-4F44-9A23-C65A63A9293EQ38536557-8BB604A4-C48A-47E7-826B-7F8B921E5FEBQ38537122-0443187D-FE72-44B5-AC75-9E10862E8DF6Q38673938-AD7D16F1-B7DA-4F16-8BEE-5C6F6B987E39Q38769185-52B94187-70AC-4455-864F-18610D819787Q38793396-57F4B7B2-2E80-4DA8-BF27-9CF1BBFEB63BQ38802133-FBC81993-8C38-48E5-B510-B559DF8BC7AF
P2860
Activating hotspot L205R mutation in PRKACA and adrenal Cushing's syndrome.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
2014年學術文章
@zh
2014年學術文章
@zh-hant
name
Activating hotspot L205R mutation in PRKACA and adrenal Cushing's syndrome.
@en
Activating hotspot L205R mutation in PRKACA and adrenal Cushing's syndrome.
@nl
type
label
Activating hotspot L205R mutation in PRKACA and adrenal Cushing's syndrome.
@en
Activating hotspot L205R mutation in PRKACA and adrenal Cushing's syndrome.
@nl
prefLabel
Activating hotspot L205R mutation in PRKACA and adrenal Cushing's syndrome.
@en
Activating hotspot L205R mutation in PRKACA and adrenal Cushing's syndrome.
@nl
P2093
P2860
P356
P1433
P1476
Activating hotspot L205R mutation in PRKACA and adrenal Cushing's syndrome.
@en
P2093
Guang Ning
Minghui He
Tingwei Su
P2860
P304
P356
10.1126/SCIENCE.1249480
P407
P577
2014-04-03T00:00:00Z