Effects of dexpramipexole on brain mitochondrial conductances and cellular bioenergetic efficiency.
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Mitochondrial dysfunction in amyotrophic lateral sclerosis - a valid pharmacological target?Mitochondrial protectant pramipexole prevents sex-specific long-term cognitive impairment from early anaesthesia exposure in rats.Mechanisms, models and biomarkers in amyotrophic lateral sclerosisCaprylic triglyceride as a novel therapeutic approach to effectively improve the performance and attenuate the symptoms due to the motor neuron loss in ALS diseaseGNX-4728, a novel small molecule drug inhibitor of mitochondrial permeability transition, is therapeutic in a mouse model of amyotrophic lateral sclerosis.Dexpramipexole is ineffective in two models of ALS related neurodegeneration.The mitochondrial complex V-associated large-conductance inner membrane current is regulated by cyclosporine and dexpramipexoleAmyotrophic lateral sclerosis and the clinical potential of dexpramipexole.The elusive magic pill: finding effective therapies for mitochondrial disordersClinical utility of neuroprotective agents in neurodegenerative diseases: current status of drug development for Alzheimer's, Parkinson's and Huntington's diseases, and amyotrophic lateral sclerosis.Predicting success: optimizing phase II ALS trials for the transition to phase III.Experimental trials in amyotrophic lateral sclerosis: a review of recently completed, ongoing and planned trials using existing and novel drugs.Metabolic Dysfunctions in Amyotrophic Lateral Sclerosis Pathogenesis and Potential Metabolic TreatmentsImplications of white matter damage in amyotrophic lateral sclerosis (Review).Dexpramipexole improves bioenergetics and outcome in experimental stroke.Energy metabolism in ALS: an underappreciated opportunity?
P2860
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P2860
Effects of dexpramipexole on brain mitochondrial conductances and cellular bioenergetic efficiency.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
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2012年學術文章
@zh-hant
name
Effects of dexpramipexole on b ...... lular bioenergetic efficiency.
@en
Effects of dexpramipexole on b ...... lular bioenergetic efficiency.
@nl
type
label
Effects of dexpramipexole on b ...... lular bioenergetic efficiency.
@en
Effects of dexpramipexole on b ...... lular bioenergetic efficiency.
@nl
prefLabel
Effects of dexpramipexole on b ...... lular bioenergetic efficiency.
@en
Effects of dexpramipexole on b ...... lular bioenergetic efficiency.
@nl
P2093
P2860
P1433
P1476
Effects of dexpramipexole on b ...... lular bioenergetic efficiency.
@en
P2093
Armando P Signore
Astrid Thomas
Damon R Demady
Elizabeth A Jonas
Emma Lazrove
Hongmei Li
Jamie E Mangold
Kambiz N Alavian
Laura Bonanni
Marco Onofrj
P2860
P356
10.1016/J.BRAINRES.2012.01.046
P577
2012-01-28T00:00:00Z