Molecular mechanism of 17-allylamino-17-demethoxygeldanamycin (17-AAG)-induced AXL receptor tyrosine kinase degradation.

Molecular mechanism of 17-allylamino-17-demethoxygeldanamycin (17-AAG)-induced AXL receptor tyrosine kinase degradation.

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http://www.wikidata.org/entity/Q42155234
AXL kinase as a novel target for cancer therapyProtein homeostasis at the plasma membraneA Decade of Boon or Burden: What Has the CHIP Ever Done for Cellular Protein Quality Control Mechanism Implicated in Neurodegeneration and Aging?AUY922 effectively overcomes MET- and AXL-mediated resistance to EGFR-TKI in lung cancer cellsHsp90-Associated Immunophilin Homolog Cpr7 Is Required for the Mitotic Stability of [URE3] Prion in Saccharomyces cerevisiae.Regulated intramembrane proteolysis of the AXL receptor kinase generates an intracellular domain that localizes in the nucleus of cancer cells.Cks1 proteasomal degradation is induced by inhibiting Hsp90-mediated chaperoning in cancer cells.ALK inhibitor resistance in ALK(F1174L)-driven neuroblastoma is associated with AXL activation and induction of EMT.MicroPET/CT Imaging of AXL Downregulation by HSP90 Inhibition in Triple-Negative Breast Cancer.Chaperone-Mediated Regulation of Choline Acetyltransferase Protein Stability and Activity by HSC/HSP70, HSP90, and p97/VCP.Novel strategy for a bispecific antibody: induction of dual target internalization and degradation.Violacein induces death of RAS-mutated metastatic melanoma by impairing autophagy process.Overcoming drug-tolerant cancer cell subpopulations showing AXL activation and epithelial-mesenchymal transition is critical in conquering ALK-positive lung cancer.
P2860

Molecular mechanism of 17-allylamino-17-demethoxygeldanamycin (17-AAG)-induced AXL receptor tyrosine kinase degradation.

Item
http://www.wikidata.org/entity/Q42155234
description
2013 nî lūn-bûn
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2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
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2013年學術文章
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name
Molecular mechanism of 17-ally ...... r tyrosine kinase degradation.
@en
Molecular mechanism of 17-allylamino-17-demethoxygeldanamycin
@nl
type
label
Molecular mechanism of 17-ally ...... r tyrosine kinase degradation.
@en
Molecular mechanism of 17-allylamino-17-demethoxygeldanamycin
@nl
prefLabel
Molecular mechanism of 17-ally ...... r tyrosine kinase degradation.
@en
Molecular mechanism of 17-allylamino-17-demethoxygeldanamycin
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P932
P356
P1433
P1476
Molecular mechanism of 17-ally ...... r tyrosine kinase degradation.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P932