Glycogen synthase kinase 3 beta mediates high glucose-induced ubiquitination and proteasome degradation of insulin receptor substrate 1.
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F-box protein FBXL19-mediated ubiquitination and degradation of the receptor for IL-33 limits pulmonary inflammationChronic over-nutrition and dysregulation of GSK3 in diseasesKnockdown of GSK3β increases basal autophagy and AMPK signalling in nutrient-laden human aortic endothelial cellsOverstimulation can create health problems due to increases in PI3K/Akt/GSK3 insensitivity and GSK3 activity.Targeting GSK-3 family members in the heart: a very sharp double-edged sword.Opposite cross-talk by oleate and palmitate on insulin signaling in hepatocytes through macrophage activationLong-Term Over-Expression of Neuropeptide Y in Hypothalamic Paraventricular Nucleus Contributes to Adipose Tissue Insulin Resistance Partly via the Y5 ReceptorHigh-Fat Diet/Low-Dose Streptozotocin-Induced Type 2 Diabetes in Rats Impacts Osteogenesis and Wnt Signaling in Bone Marrow Stromal CellsEnhancement of 26S proteasome functionality connects oxidative stress and vascular endothelial inflammatory response in diabetes mellitus.Insulin and diet-induced changes in the ubiquitin-modified proteome of rat liver.Natural Functions of PLIN2 Mediating Wnt/LiCl Signaling and Glycogen Synthase Kinase 3 (GSK3)/GSK3 Substrate-Related Effects Are Modulated by LipidLRP6 enhances glucose metabolism by promoting TCF7L2-dependent insulin receptor expression and IGF receptor stabilization in humans.Estrogen and ERα enhanced β-catenin degradation and suppressed its downstream target genes to block the metastatic function of HA22T hepatocellular carcinoma cells via modulating GSK-3β and β-TrCP expression.Akt2 knockout mitigates chronic iNOS inhibition-induced cardiomyocyte atrophy and contractile dysfunction despite persistent insulin resistance.Essential role of protein-tyrosine phosphatase 1B in the modulation of insulin signaling by acetaminophen in hepatocytes.GSK-3α is a central regulator of age-related pathologies in mice.Genetic variations in the PSMA3, PSMA6 and PSMC6 genes are associated with type 1 diabetes in Latvians and with expression level of number of UPS-related and T1DM-susceptible genes in HapMap individuals.GSK-3β inhibition protects mesothelial cells during experimental peritoneal dialysis through upregulation of the heat shock response.Curcumin Improves Palmitate-Induced Insulin Resistance in Human Umbilical Vein Endothelial Cells by Maintaining Proteostasis in Endoplasmic ReticulumAntidiabetic and vasoprotective activity of lithium: Role of glycogen synthase kinase-3.The deubiquitinating enzyme USP48 stabilizes TRAF2 and reduces E-cadherin-mediated adherens junctions.Microcystin-LR disrupts insulin signaling by hyperphosphorylating insulin receptor substrate 1 and glycogen synthase.Mild alcohol intake exacerbates metabolic syndrome in rodents: a putative role of GSK-3β.Correlation between tuberous sclerosis complex 2 and glycogen synthase kinase 3 beta levels, and outcomes of patients with hepatocellular carcinoma treated by hepatectomy.
P2860
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P2860
Glycogen synthase kinase 3 beta mediates high glucose-induced ubiquitination and proteasome degradation of insulin receptor substrate 1.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Glycogen synthase kinase 3 bet ...... insulin receptor substrate 1.
@en
Glycogen synthase kinase 3 bet ...... insulin receptor substrate 1.
@nl
type
label
Glycogen synthase kinase 3 bet ...... insulin receptor substrate 1.
@en
Glycogen synthase kinase 3 bet ...... insulin receptor substrate 1.
@nl
prefLabel
Glycogen synthase kinase 3 bet ...... insulin receptor substrate 1.
@en
Glycogen synthase kinase 3 bet ...... insulin receptor substrate 1.
@nl
P2093
P2860
P356
P1476
Glycogen synthase kinase 3 bet ...... insulin receptor substrate 1.
@en
P2093
Christopher J Rhodes
Sanhua Leng
Wenshuo Zhang
Xiao Jian Sun
Yanbin Zheng
Ziva Liberman
P2860
P304
P356
10.1677/JOE-09-0456
P407
P577
2010-05-13T00:00:00Z