Bovine insulin filaments induced by reducing disulfide bonds show a different morphology, secondary structure, and cell toxicity from intact insulin amyloid fibrils
about
The impact of protein disulfide bonds on the amyloid fibril morphology.Oligomeric forms of insulin amyloid aggregation disrupt outgrowth and complexity of neuron-like PC12 cells.Disulfide bridges remain intact while native insulin converts into amyloid fibrilsInhibition study on insulin fibrillation and cytotoxicity by paclitaxel.Effect of mid-infrared free-electron laser irradiation on refolding of amyloid-like fibrils of lysozyme into native formProtonation favors aggregation of lysozyme with SDS.Curcumin Protects β-Lactoglobulin Fibril Formation and Fibril-Induced Neurotoxicity in PC12 Cells.Surface characterization of insulin protofilaments and fibril polymorphs using tip-enhanced Raman spectroscopy (TERS).Amyloid oligomers: spectroscopic characterization of amyloidogenic protein states.Physico-chemical stress induced amyloid formation in insulin: Amyloid characterization, cytotoxicity analysis against human neuroblastoma cell lines and its prevention using black seeds (Nigella sativa).Apigenin modulates the expression levels of pro-inflammatory mediators to reduce the human insulin amyloid-induced oxidant damages in SK-N-MC cells.Inhibition of insulin fibrillation by osmolytes: Mechanistic insights.Oligomerization of neutral peptides derived from the JC virus agnoprotein through a cysteine residue.Nanoscopic and photonic ultrastructural characterization of two distinct insulin amyloid states.Inhibitory effects of arginine on the aggregation of bovine insulin.Freeze-dried and spray-dried zinc-containing silica microparticles entrapping insulin.Cysteine inhibits the fibrillisation and cytotoxicity of amyloid-β 40 and 42: implications for the contribution of the thiophilic interaction.Tip-Enhanced Raman Spectroscopy: a Tool for Nanoscale Chemical and Structural Characterization of Biomolecules.Detection and structural characterization of insulin prefibrilar oligomers using surface enhanced Raman spectroscopy.Elucidation of insulin assembly at acidic and neutral pH: Characterization of low molecular weight oligomers.The thioredoxin system and not the Michaelis-Menten equation should be fitted to substrate saturation datasets from the thioredoxin insulin assay.Role of the Disulfide Bond in Prion Protein Amyloid Formation: A Thermodynamic and Kinetic Analysis.Appearance of annular ring-like intermediates during amyloid fibril formation from human serum albumin.
P2860
Q30360911-2DCBF47C-B4A7-4A36-AB57-B24A14660D92Q34291460-768753E5-E946-4AFB-AD63-3A277BE1C304Q34295554-FA60C4BF-DBF3-4F55-A693-8DAA60631424Q34404870-FD7E82E0-8B12-4D07-8058-F0746CA9B2A7Q34440267-C054279E-77DC-4411-A57E-7223C4686F4BQ35125277-AF891070-21BB-4605-ABEA-B546C58D447EQ35694684-BC3BC819-9164-44EA-9EE4-6FFD9531D72DQ37533492-D6D286DE-723E-49E7-9E74-EF2B768133B2Q37690818-0C5CAAA7-C821-41E5-8E8D-3816431BF20CQ38875824-77CC3C95-4537-4455-A7C3-1B46BCA60230Q38948962-7B767B5D-51B1-47EF-BAD9-AF538EE66733Q40264377-9675FC74-902C-477C-AD24-99D4B1B342EBQ41224896-E053B051-BD77-4787-A7B9-310989BCEAD0Q41828490-4214FF92-DDE7-496A-8291-C5B4AE681AFFQ42184618-EF8EEBBC-BDFB-42CC-BA6C-BAB1E47794F5Q43814476-51ACE790-7B1F-4C99-87F5-D72972EC6DFFQ44251485-F4B98905-AA0D-46DA-BDC8-A35EAC265CE9Q46268100-D4E44E27-DC18-4A9B-B098-7B0D2A43C821Q46953117-41EC9077-67CB-46A1-8FB3-703ABD1A83CBQ47195044-3EF99407-4B18-47B6-933B-2E92887D1A14Q50894349-E547753B-66DD-4E00-81FA-37AF7BCDC1D2Q51746419-46F0A84A-CCC5-462F-B53C-0E50BE15502FQ51812569-37A70E12-B535-497E-887E-E47BD7715898
P2860
Bovine insulin filaments induced by reducing disulfide bonds show a different morphology, secondary structure, and cell toxicity from intact insulin amyloid fibrils
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Bovine insulin filaments induc ...... intact insulin amyloid fibrils
@en
Bovine insulin filaments induc ...... intact insulin amyloid fibrils
@nl
type
label
Bovine insulin filaments induc ...... intact insulin amyloid fibrils
@en
Bovine insulin filaments induc ...... intact insulin amyloid fibrils
@nl
prefLabel
Bovine insulin filaments induc ...... intact insulin amyloid fibrils
@en
Bovine insulin filaments induc ...... intact insulin amyloid fibrils
@nl
P2093
P2860
P1433
P1476
Bovine insulin filaments induc ...... intact insulin amyloid fibrils
@en
P2093
Masaki Ihara
Mizuo Maeda
Naomi Hashimoto
Tamotsu Zako
P2860
P304
P356
10.1016/J.BPJ.2008.12.3957
P407
P577
2009-04-01T00:00:00Z