Peripheral blood monocytes are responsible for gammadelta T cell activation induced by zoledronic acid through accumulation of IPP/DMAPP.
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Managing osteoporosis in ulcerative colitis: something new?γδ T cell and other immune cells crosstalk in cellular immunityHarnessing the power of Vδ2 cells in cancer immunotherapyγδ T cells in cancer immunotherapyEndocytotic uptake of zoledronic acid by tubular cells may explain its renal effects in cancer patients receiving high doses of the compoundAnti-leukemia activity of in vitro-expanded human gamma delta T cells in a xenogeneic Ph+ leukemia modelAnti-Tumor Activity and Immunotherapeutic Potential of a Bisphosphonate Prodrug.Expanded Human Blood-Derived γδT Cells Display Potent Antigen-Presentation Functions.Long-term treatment with bisphosphonates and their safety in postmenopausal osteoporosis.Targeting γδ T cells for immunotherapy of HIV diseaseNovel immunostimulatory effects of osteoclasts and macrophages on human γδ T cells.Liposome encapsulated zoledronate favours M1-like behaviour in murine macrophages cultured with soluble factors from breast cancer cells.Do γδ T cells predict osteonecrosis of the jaw?Regulation of development of CD56 bright CD11c + NK-like cells with helper function by IL-18.Effect of acetaminophen and fluvastatin on post-dose symptoms following infusion of zoledronic acid.Increased prevalence of bisphosphonate-related osteonecrosis of the jaw with vitamin D deficiency in rats.Fluorescent risedronate analogues reveal bisphosphonate uptake by bone marrow monocytes and localization around osteocytes in vivoChallenges and future perspectives of T cell immunotherapy in cancerIndirect stimulation of human Vγ2Vδ2 T cells through alterations in isoprenoid metabolism.Influence of bisphosphonate treatment on medullary macrophages and osteoclasts: an experimental study.A highly sensitive prenylation assay reveals in vivo effects of bisphosphonate drug on the Rab prenylome of macrophages outside the skeleton.Interleukin-15 enhances the proliferation, stimulatory phenotype, and antitumor effector functions of human gamma delta T cellsActivated γδ T cells inhibit osteoclast differentiation and resorptive activity in vitro.Bisphosphonamidate clodronate prodrug exhibits selective cytotoxic activity against melanoma cell lines.Enhancing adoptive cancer immunotherapy with Vγ2Vδ2 T cells through pulse zoledronate stimulationIntraperitoneal injection of in vitro expanded Vγ9Vδ2 T cells together with zoledronate for the treatment of malignant ascites due to gastric cancer.Anticancer properties of zoledronic acid.Pharmacokinetic evaluation of zoledronic acid.γδ T-APCs: a novel tool for immunotherapy?Vγ9Vδ2 T cell-based immunotherapy in hematological malignancies: from bench to bedside.New perspectives on zoledronic acid in breast cancer: potential augmentation of anticancer immune response.New role for an established drug? Bisphosphonates as potential anticancer agents.Potential therapeutic effects of oral bisphosphonates on the intestine.The multifunctionality of human Vγ9Vδ2 γδ T cells: clonal plasticity or distinct subsets?Human γδ T-cell responses in infection and immunotherapy: common mechanisms, common mediators?Anti-tumour immunotherapy with Vγ9Vδ2 T lymphocytes: from the bench to the bedside.At the Bedside: Innate immunity as an immunotherapy tool for hematological malignancies.Current and future approaches to treat graft failure after allogeneic hematopoietic stem cell transplantation.Potential Use of γδ T Cell-Based Vaccines in Cancer Immunotherapy.Tumor-Infiltrating γδ T Lymphocytes: Pathogenic Role, Clinical Significance, and Differential Programing in the Tumor Microenvironment.
P2860
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P2860
Peripheral blood monocytes are responsible for gammadelta T cell activation induced by zoledronic acid through accumulation of IPP/DMAPP.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Peripheral blood monocytes are ...... ugh accumulation of IPP/DMAPP.
@en
Peripheral blood monocytes are ...... ugh accumulation of IPP/DMAPP.
@nl
type
label
Peripheral blood monocytes are ...... ugh accumulation of IPP/DMAPP.
@en
Peripheral blood monocytes are ...... ugh accumulation of IPP/DMAPP.
@nl
prefLabel
Peripheral blood monocytes are ...... ugh accumulation of IPP/DMAPP.
@en
Peripheral blood monocytes are ...... ugh accumulation of IPP/DMAPP.
@nl
P2093
P2860
P1476
Peripheral blood monocytes are ...... ough accumulation of IPP/DMAPP
@en
P2093
Anke J Roelofs
Hannu Mönkkönen
Jukka Mönkkönen
Marjo Jauhiainen
P2860
P304
P356
10.1111/J.1365-2141.2008.07435.X
P407
P577
2008-11-07T00:00:00Z