Metabolic activation of intrahepatic CD8+ T cells and NKT cells causes nonalcoholic steatohepatitis and liver cancer via cross-talk with hepatocytes.
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Nonalcoholic Lipid Accumulation and Hepatocyte Malignant TransformationUtilization of animal models to investigate non-alcoholic steatohepatitis-associated hepatocellular carcinomaHepatocellular carcinoma and non-alcoholic steatohepatitis: The state of playNKT cell subsets as key participants in liver physiology and pathologyIL-17 Axis Driven Inflammation in Non-Alcoholic Fatty Liver Disease ProgressionAn orthotopic mouse model of hepatocellular carcinoma with underlying liver cirrhosis.The necroptosis-inducing kinase RIPK3 dampens adipose tissue inflammation and glucose intolerance.Hepatocellular carcinoma in patients with non-alcoholic fatty liver diseaseImmune Imbalances in Non-Alcoholic Fatty Liver Disease: From General Biomarkers and Neutrophils to Interleukin-17 Axis Activation and New Therapeutic TargetsImmune surveillance of liver cancer in non-alcoholic fatty liver disease: excess lipids cause CD4 T-cells loss and promote hepatocellular carcinoma developmentInhibition of citrate cotransporter Slc13a5/mINDY by RNAi improves hepatic insulin sensitivity and prevents diet-induced non-alcoholic fatty liver disease in mice.Serotonin Activated Hepatic Stellate Cells Contribute to Sex Disparity in Hepatocellular Carcinoma.Death Receptor-Mediated Cell Death and Proinflammatory Signaling in Nonalcoholic Steatohepatitis.Histologic Assessment of Intratumoral Lymphoplasmacytic Infiltration Is Useful in Predicting Prognosis of Patients with Hepatocellular Carcinoma.Development of a novel mouse model of hepatocellular carcinoma with nonalcoholic steatohepatitis using a high-fat, choline-deficient diet and intraperitoneal injection of diethylnitrosamineImmunity, inflammation, and cancer: an eternal fight between good and evil.Animal Models Correlating Immune Cells for the Development of NAFLD/NASH.NAFLD causes selective CD4(+) T lymphocyte loss and promotes hepatocarcinogenesis.CDR3β sequence motifs regulate autoreactivity of human invariant NKT cell receptors.LTβR signalling preferentially accelerates oncogenic AKT-initiated liver tumoursEnterogenous bacterial glycolipids are required for the generation of natural killer T cells mediated liver injuryA20 prevents chronic liver inflammation and cancer by protecting hepatocytes from death.Animal models of non-alcoholic fatty liver disease: current perspectives and recent advances.The immunoreceptor NKG2D promotes tumour growth in a model of hepatocellular carcinoma.Homeostasis of IL-15 dependent lymphocyte subsets in the liver.Current concepts of immune based treatments for patients with HCC: from basic science to novel treatment approaches.Natural killer T cells in liver injury, inflammation and cancer.Is there a role for adaptive immunity in nonalcoholic steatohepatitis?Recent advances in mouse models of obesity- and nonalcoholic steatohepatitis-associated hepatocarcinogenesis.Mutant p53 in concert with an interleukin-27 receptor alpha deficiency causes spontaneous liver inflammation, fibrosis, and steatosis in miceThe role of infiltrating immune cells in dysfunctional adipose tissue.The role of immune mechanisms in alcoholic and nonalcoholic steatohepatitis: a 2015 update.Gut microbiota changes and chronic hepatitis C virus infection.Immunology in the liver--from homeostasis to disease.IL6-mediated inflammatory loop reprograms normal to epithelial-mesenchymal transition+ metastatic cancer stem cells in preneoplastic liver of transforming growth factor beta-deficient β2-spectrin+/- mice.Changes in drug transport and metabolism and their clinical implications in non-alcoholic fatty liver disease.Hepatocellular Carcinoma in Obesity, Type 2 Diabetes, and NAFLD.Hepatoma cell-derived leptin downregulates the immunosuppressive function of regulatory T-cells to enhance the anti-tumor activity of CD8+ T-cells.Lymphotoxin in physiology of lymphoid tissues - Implication for antiviral defense.Dual Shp2 and Pten Deficiencies Promote Non-alcoholic Steatohepatitis and Genesis of Liver Tumor-Initiating Cells.
P2860
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P2860
Metabolic activation of intrahepatic CD8+ T cells and NKT cells causes nonalcoholic steatohepatitis and liver cancer via cross-talk with hepatocytes.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
2014年學術文章
@zh
2014年學術文章
@zh-hant
name
Metabolic activation of intrah ...... a cross-talk with hepatocytes.
@en
Metabolic activation of intrah ...... a cross-talk with hepatocytes.
@nl
type
label
Metabolic activation of intrah ...... a cross-talk with hepatocytes.
@en
Metabolic activation of intrah ...... a cross-talk with hepatocytes.
@nl
prefLabel
Metabolic activation of intrah ...... a cross-talk with hepatocytes.
@en
Metabolic activation of intrah ...... a cross-talk with hepatocytes.
@nl
P2093
P50
P1433
P1476
Metabolic activation of intrah ...... a cross-talk with hepatocytes.
@en
P2093
Achim Weber
Alexei V Tumanov
Arlind Adili
Christoph Thiele
Claudia Einer
Dirk Wohlleber
Holger Moch
Kira Piotrowitz
Michèle Egger
Monika Julia Wolf
P304
P356
10.1016/J.CCELL.2014.09.003
P407
P50
P577
2014-10-01T00:00:00Z