about
Immune Mechanisms in Myelodysplastic Syndrome31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part oneHigh-throughput T-cell epitope discovery through MHC peptide exchange.The immune system strikes back: cellular immune responses against indoleamine 2,3-dioxygenase.Evolution of MHC-based technologies used for detection of antigen-responsive T cellsInfluence of ipilimumab on expanded tumour derived T cells from patients with metastatic melanoma.Preclinical evaluation of NF-κB-triggered dendritic cells expressing the viral oncogenic driver of Merkel cell carcinoma for therapeutic vaccination.Longitudinal studies of clonally expanded CD8 T cells reveal a repertoire shrinkage predicting mortality and an increased number of dysfunctional cytomegalovirus-specific T cells in the very elderly.Conditional ligands for Asian HLA variants facilitate the definition of CD8+ T-cell responses in acute and chronic viral diseases.Parallel detection of antigen-specific T-cell responses by multidimensional encoding of MHC multimers.High-throughput identification of antigen-specific TCRs by TCR gene capture.Comment on "5-azacytidine promotes an inhibitory T-cell phenotype and impairs immune mediated antileukemic activity"Broadening the repertoire of melanoma-associated T-cell epitopes.TIL therapy broadens the tumor-reactive CD8(+) T cell compartment in melanoma patients.MuPeXI: prediction of neo-epitopes from tumor sequencing data.Adoptive cell therapy with autologous tumor infiltrating lymphocytes and low-dose Interleukin-2 in metastatic melanoma patients.Conditional MHC class I ligands and peptide exchange technology for the human MHC gene products HLA-A1, -A3, -A11, and -B7Thinking outside the gate: single-cell assessments in multiple dimensionsDiscovering naturally processed antigenic determinants that confer protective T cell immunity.Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade.Modular nucleic acid assembled p/MHC microarrays for multiplexed sorting of antigen-specific T cells.MHC-based detection of antigen-specific CD8+ T cell responses.5-Azacytidine treatment sensitizes tumor cells to T-cell mediated cytotoxicity and modulates NK cells in patients with myeloid malignancies.Automated Analysis of Flow Cytometry Data to Reduce Inter-Lab Variation in the Detection of Major Histocompatibility Complex Multimer-Binding T Cells.Acquired Immune Resistance Follows Complete Tumor Regression without Loss of Target Antigens or IFNγ Signaling.Neoantigen landscape dynamics during human melanoma-T cell interactions.T-cell responses to oncogenic merkel cell polyomavirus proteins distinguish patients with merkel cell carcinoma from healthy donors.PD-1+ Polyfunctional T Cells Dominate the Periphery after Tumor-Infiltrating Lymphocyte Therapy for Cancer.Large-scale detection of antigen-specific T cells using peptide-MHC-I multimers labeled with DNA barcodes.High frequency of T cells specific for cryptic epitopes in melanoma patientsCryopreservation of MHC multimers: Recommendations for quality assurance in detection of antigen specific T cells."Immunotherapy of cancer: present status and future promise": Danish Cancer Society Symposium, Copenhagen, Denmark, 23rd-25th September 2013.Effector CD4 and CD8 T cells and their role in the tumor microenvironment.Vaccination with autologous dendritic cells pulsed with multiple tumor antigens for treatment of patients with malignant melanoma: results from a phase I/II trial.CD8 T-cell responses against cyclin B1 in breast cancer patients with tumors overexpressing p53.Discovery of CD8 T cell epitopes in Merkel cell polyomavirus through combinatorial encoding with MHC multimers.Effects of Ipilimumab on expanded tumor infiltrating lymphocytes in patients with stage IV malignant melanoma.Toward next-generation cancer immunotherapy: 10th annual meeting of the Association for Cancer Immunotherapy (CIMT), Mainz, Germany, May 23-25, 2012.An Analysis of Natural T Cell Responses to Predicted Tumor Neoepitopes.Generation of autologous tumor-specific T cells for adoptive transfer based on vaccination, in vitro restimulation and CD3/CD28 dynabead-induced T cell expansion.
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P-3388-2014
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2000-01-01T00:00:00Z