about
Synthesis and cytotoxicity of pyranonaphthoquinone natural product analogues under bioreductive conditions.Pyranonaphthoquinones--isolation, biological activity and synthesis.Isolation, biological activity and synthesis of benzannulated spiroketal natural products.Natural products containing a nitrogen-nitrogen bond.Targeting isocitrate lyase for the treatment of latent tuberculosis.4,4'-Bismoschamine: biomimetic synthesis and evidence to support structural equivalency to montamine.Mushroom-Derived Indole Alkaloids.Synthesis of Inducamides A and B.Synthesis of Alocasin A.Synthesis and electrochemical detection of a thiazolyl-indole natural product isolated from the nosocomial pathogen Pseudomonas aeruginosa.Alkaloids from the Traditional Chinese Medicine ChanSu: synthesis-enabled structural reassignment of bufopyramide to bufoserotonin C.Discovery of a 1,2-bis(3-indolyl)ethane that selectively inhibits the pyruvate kinase of methicillin-resistant Staphylococcus aureus over human isoforms.(1R,1'R,3S,3'S)-5,5',10,10'-Tetra-meth-oxy-1,1',3,3'-tetra-methyl-3,3',4,4'-tetra-hydro-1H,1'H-8,8'-bi[benzo[g]isochromene].Synthesis and evaluation of 9-deoxy analogues of (-)-thysanone, an inhibitor of HRV 3C protease.Synthesis of the 2-methylene analogue of the HRV 3C protease inhibitor thysanone (2-carbathysanone).Heteroatom-directed reverse Wacker oxidations. Synthesis of the reported structure of (-)-herbaric acid.Synthesis of natural products containing spiroketals via intramolecular hydrogen abstraction.Pyranonaphthoquinone derivatives of eleutherin, ventiloquinone L, thysanone and nanaomycin A possessing a diverse topoisomerase II inhibition and cytotoxicity spectrum.Schischkiniin support studies: synthetic access to 1,1'-bisindoles.Biomimetic studies towards the cardinalins: synthesis of (+)-ventiloquinone L and an unusual dimerisation.Enantioselective synthesis of the dimeric pyranonaphthoquinone core of the cardinalins using a late-stage homocoupling strategy.Towards the Shell Biorefinery: Sustainable Synthesis of the Anticancer Alkaloid Proximicin A from Chitin.Natural Products with Heteroatom-Rich Ring Systems.Synthetic studies towards putative yuremamine using an iterative C(sp(3))-H arylation strategy.Total syntheses of (±)-spiroindimicins B and C enabled by a late-stage Schöllkopf-Magnus-Barton-Zard (SMBZ) reaction.Total synthesis of (-)-aspergilazine A.Bioinspired Total Synthesis and Stereochemical Revision of the Fungal Metabolite Pestalospirane B.Flavoalkaloids-Isolation, Biological Activity, and Total Synthesis.The Oxidation of Amides to Imides: A Powerful Synthetic TransformationProduction of Levoglucosenone and Dihydrolevoglucosenone by Catalytic Reforming of Volatiles from Cellulose Pyrolysis Using Supported Ionic Liquid PhaseBio-Based Chiral Amines via Aza-Michael Additions to (-)-Levoglucosenone Under Aqueous ConditionsHeterocycle construction using the biomass-derived building block itaconic acidFormal synthesis of nanaomycin D via a Hauser–Kraus annulation using a chiral enone-lactoneIridium-Catalysed C–H Borylation Facilitates a Total Synthesis of the HRV 3C Protease Inhibitor (±)-ThysanoneSynthesis and Biological Evaluation of 7-Deoxy Analogues of the Human Rhinovirus 3C Protease Inhibitor ThysanoneToward an Asymmetric Synthesis of the Dimeric Pyranonaphthoquinone Antibiotic Crisamicin ANatural Product-Inspired Pyranonaphthoquinone Inhibitors of Indoleamine 2,3-Dioxygenase-1 (IDO-1)Telomerase Inhibition Studies of Novel Spiroketal-Containing Rubromycin DerivativesA simple solid phase, peptide-based fluorescent assay for the efficient and universal screening of HRV 3C protease inhibitorsSynthesis of the Tetracyclic Core of Berkelic Acid Using Gold(I)-Catalyzed Hydroarylation and Oxidative Radical Cyclizations
P50
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Jonathan Sperry
@ast
Jonathan Sperry
@en
Jonathan Sperry
@es
Jonathan Sperry
@nl
Jonathan Sperry
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type
label
Jonathan Sperry
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Jonathan Sperry
@en
Jonathan Sperry
@es
Jonathan Sperry
@nl
Jonathan Sperry
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prefLabel
Jonathan Sperry
@ast
Jonathan Sperry
@en
Jonathan Sperry
@es
Jonathan Sperry
@nl
Jonathan Sperry
@sl
P106
P1153
35235030000
P21
P31
P496
0000-0001-7288-3939