about
Lysyl hydroxylase 3 is a multifunctional protein possessing collagen glucosyltransferase activity.The third activity for lysyl hydroxylase 3: galactosylation of hydroxylysyl residues in collagens in vitro.Regulation of post-Golgi LH3 trafficking is essential for collagen homeostasisLysyl hydroxylase 3 (LH3) modifies proteins in the extracellular space, a novel mechanism for matrix remodeling.The activities of lysyl hydroxylase 3 (LH3) regulate the amount and oligomerization status of adiponectin.Natural antibodies of newborns recognize oxidative stress-related malondialdehyde acetaldehyde adducts on apoptotic cells and atherosclerotic plaques.A purified MAA-based ELISA is a useful tool for determining anti-MAA antibody titer with high sensitivity.Natural Monoclonal Antibody to Oxidized Low-Density Lipoprotein and Aggregatibacter actinomycetemcomitans.Cross-reactive saliva IgA antibodies to oxidized LDL and periodontal pathogens in humans.Lysyl hydroxylase 3 is secreted from cells by two pathways.Immunization with malondialdehyde-modified low-density lipoprotein (LDL) reduces atherosclerosis in LDL receptor-deficient mice challenged with Porphyromonas gingivalis.Systematic screening of soluble expression of antibody fragments in the cytoplasm of E. coli.Immunization with gingipain A hemagglutinin domain of Porphyromonas gingivalis induces IgM antibodies binding to malondialdehyde-acetaldehyde modified low-density lipoprotein.IgA antibodies to phosphocholine associate with long-term cardiovascular disease risk.Characterization of a natural mouse monoclonal antibody recognizing epitopes shared by oxidized low-density lipoprotein and chaperonin 60 of Aggregatibacter actinomycetemcomitans.Human monoclonal Fab and human plasma antibodies to carbamyl-epitopes cross-react with malondialdehyde-adductsSecretion and assembly of type IV and VI collagens depend on glycosylation of hydroxylysinesCarbamyl adducts on low-density lipoprotein induce IgG response in LDLR-/- mice and bind plasma autoantibodies in humans under enhanced carbamylationHumoral immune response to heat shock protein 60 of Aggregatibacter actinomycetemcomitans and cross-reactivity with malondialdehyde acetaldehyde-modified LDLSalivary IgA to MAA-LDL and Oral Pathogens Are Linked to Coronary Disease
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description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Chunguang Wang
@ast
Chunguang Wang
@en
Chunguang Wang
@es
Chunguang Wang
@nl
Chunguang Wang
@sl
type
label
Chunguang Wang
@ast
Chunguang Wang
@en
Chunguang Wang
@es
Chunguang Wang
@nl
Chunguang Wang
@sl
prefLabel
Chunguang Wang
@ast
Chunguang Wang
@en
Chunguang Wang
@es
Chunguang Wang
@nl
Chunguang Wang
@sl
P106
P1153
55684057600
P31
P496
0000-0001-5569-321X