Genome-wide siRNA screen reveals coupling between mitotic apoptosis and adaptation - Wikidata - awgldk - TriplyDB

Genome-wide siRNA screen reveals coupling between mitotic apoptosis and adaptation

Genome-wide siRNA screen reveals coupling between mitotic apoptosis and adaptation

http://www.wikidata.org/entity/Q42207747

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Hanging on for the ride: adhesion to the extracellular matrix mediates cellular responses in skeletal muscle morphogenesis and disease The NOXA-MCL1-BIM axis defines lifespan on extended mitotic arrest The Cdc20-binding Phe box of the spindle checkpoint protein BubR1 maintains the mitotic checkpoint complex during mitosis.MYC Is a Major Determinant of Mitotic Cell Fate.Paclitaxel and the dietary flavonoid fisetin: a synergistic combination that induces mitotic catastrophe and autophagic cell death in A549 non-small cell lung cancer cells.The Bub1-Plk1 kinase complex promotes spindle checkpoint signalling through Cdc20 phosphorylation.AMPK and PFKFB3 mediate glycolysis and survival in response to mitophagy during mitotic arrest.Inhibition of Bcl-xL sensitizes cells to mitotic blockers, but not mitotic drivers.Mcl-1 dynamics influence mitotic slippage and death in mitosis.Graded requirement for the spliceosome in cell cycle progression Paclitaxel-induced aberrant mitosis and mitotic slippage efficiently lead to proliferative death irrespective of canonical apoptosis and p53.The complexity of life and death decisions in mitosis.Stop competing, start talking!The Ndc80 complex targets Bod1 to human mitotic kinetochores.Perturbing mitosis for anti-cancer therapy: is cell death the only answer?Exploiting the pro-apoptotic function of NOXA as a therapeutic modality in cancer.Universal response in the RKO colon cancer cell line to distinct antimitotic therapies.

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P2860

Genome-wide siRNA screen reveals coupling between mitotic apoptosis and adaptation

http://www.wikidata.org/entity/Q42207747

description

2014 nî lūn-bûn

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

Genome-wide siRNA screen reveals coupling between mitotic apoptosis and adaptation

@en

Genome-wide siRNA screen reveals coupling between mitotic apoptosis and adaptation

@nl

type

label

Genome-wide siRNA screen reveals coupling between mitotic apoptosis and adaptation

@en

Genome-wide siRNA screen reveals coupling between mitotic apoptosis and adaptation

@nl

prefLabel

Genome-wide siRNA screen reveals coupling between mitotic apoptosis and adaptation

@en

Genome-wide siRNA screen reveals coupling between mitotic apoptosis and adaptation

@nl

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The EMBO Journal

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Genome-wide siRNA screen reveals coupling between mitotic apoptosis and adaptation

@en

P2093

Bing Li

http://www.w3.org/2001/XMLSchema#string

Hongtao Yu

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Laura A Díaz-Martínez

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Ross Warrington

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Shuguang Wei

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Xian-Jin Xie

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Zemfira N Karamysheva

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Re-evaluating the role of Tao1 in the spindle checkpoint

p31comet blocks Mad2 activation through structural mimicry

A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1

Determinants of conformational dimerization of Mad2 and its inhibition by p31comet

Identification of a MAD2-binding protein, CMT2, and its role in mitosis.

Checkpoint protein BubR1 acts synergistically with Mad2 to inhibit anaphase-promoting complex

Conformation-specific binding of p31(comet) antagonizes the function of Mad2 in the spindle checkpoint

The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation

Mitotic checkpoint slippage in humans occurs via cyclin B destruction in the presence of an active checkpoint.

Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2

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1960-1976

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scholarly article

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10.15252/EMBJ.201487826

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17

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33

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Laura A Díaz-Martínez

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2014-07-14T00:00:00Z

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263895195

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25024437

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4195789

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