about
Nonstructural Proteins Are Preferential Positive Selection Targets in Zika Virus and Related FlavivirusesA regulatory polymorphism in HAVCR2 modulates susceptibility to HIV-1 infectionThe evolutionary history of genes involved in spoken and written language: beyond FOXP2.Evolutionary insights into host-pathogen interactions from mammalian sequence data.Determining multiallelic complex copy number and sequence variation from high coverage exome sequencing dataAncient and recent selective pressures shaped genetic diversity at AIM2-like nucleic acid sensors.A functional variant in ERAP1 predisposes to multiple sclerosis.Mammalian NPC1 genes may undergo positive selection and human polymorphisms associate with type 2 diabetes.Genetic adaptation of the human circadian clock to day-length latitudinal variations and relevance for affective disorders.Albuminoid genes: evolving at the interface of dispensability and selectionAn evolutionary analysis of antigen processing and presentation across different timescales reveals pervasive selection.Evolution of the rapidly mutating human salivary agglutinin gene (DMBT1) and population subsistence strategy.OASes and STING: adaptive evolution in concertAn evolutionary history of the selectin gene cluster in humans.Susceptibility to type 2 diabetes may be modulated by haplotypes in G6PC2, a target of positive selection.Extensive Positive Selection Drives the Evolution of Nonstructural Proteins in Lineage C Betacoronaviruses.REST, a master regulator of neurogenesis, evolved under strong positive selection in humans and in non human primates.Distinct selective forces and Neanderthal introgression shaped genetic diversity at genes involved in neurodevelopmental disorders.TLR3 Mutations in Adult Patients With Herpes Simplex Virus and Varicella-Zoster Virus Encephalitis.Molecular Evolution of Human Coronavirus Genomes.A 6-amino acid insertion/deletion polymorphism in the mucin domain of TIM-1 confers protections against HIV-1 infection.Positive Selection Drives Evolution at the Host-Filovirus Interaction Surface.Evolutionary analysis of Old World arenaviruses reveals a major adaptive contribution of the viral polymerase.The heptad repeat region is a major selection target in MERS-CoV and related coronaviruses.Positive selection underlies the species-specific binding of Plasmodium falciparum RH5 to human basigin.The mammalian complement system as an epitome of host-pathogen genetic conflicts.Diverse selective regimes shape genetic diversity at ADAR genes and at their coding targets.Evolutionary analysis identifies an MX2 haplotype associated with natural resistance to HIV-1 infection.RIG-I-like receptors evolved adaptively in mammals, with parallel evolution at LGP2 and RIG-I.Crohn's disease loci are common targets of protozoa-driven selection.A trans-specific polymorphism in ZC3HAV1 is maintained by long-standing balancing selection and may confer susceptibility to multiple sclerosis.Natural Selection at the Brush-Border: Adaptations to Carbohydrate Diets in Humans and Other Mammals.A 175 million year history of T cell regulatory molecules reveals widespread selection, with adaptive evolution of disease alleles.Evolutionary analysis of the contact system indicates that kininogen evolved adaptively in mammals and in human populations.The role of READ1 and KIAA0319 genetic variations in developmental dyslexia: testing main and interactive effects.A common genetic variant in FOXP2 is associated with language-based learning (dis)abilities: Evidence from two Italian independent samples.Origin and dispersal of Hepatitis E virus.Long-standing balancing selection in the THBS4 gene: influence on sex-specific brain expression and gray matter volumes in Alzheimer disease.A nonsense polymorphism (R392X) in TLR5 protects from obesity but predisposes to diabetes.Variants in SNAP25 are targets of natural selection and influence verbal performances in women.
P50
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Diego Forni
@ast
Diego Forni
@en
Diego Forni
@es
Diego Forni
@nl
Diego Forni
@sl
type
label
Diego Forni
@ast
Diego Forni
@en
Diego Forni
@es
Diego Forni
@nl
Diego Forni
@sl
prefLabel
Diego Forni
@ast
Diego Forni
@en
Diego Forni
@es
Diego Forni
@nl
Diego Forni
@sl
P1053
K-5643-2016
P106
P1153
42061314700
P21
P31
P3829
P496
0000-0001-9291-5352