RP 67580, a selective antagonist of neurokinin-1 receptors, modifies some of the naloxone-precipitated morphine withdrawal signs in rats.
about
The role of spinal neuropeptides and prostaglandins in opioid physical dependenceBi- or multifunctional opioid peptide drugs.Increased morphine analgesia and reduced side effects in mice lacking the tac1 gene.Expression of mu opioid receptor in dorsal diencephalic conduction system: new insights for the medial habenula.Neurobiology of addiction: a neurocircuitry analysis.Effects of the NK1 antagonist, aprepitant, on response to oral and intranasal oxycodone in prescription opioid abusers.An in vitro model of morphine withdrawal manifests the enhancing effect on human immunodeficiency virus infection of human T lymphocytes through the induction of substance P.Improving opioid effectiveness: from ideas to evidence.Opioid-like effects of the neurokinin 1 antagonist aprepitant in patients maintained on and briefly withdrawn from methadone.Building a better analgesic: multifunctional compounds that address injury-induced pathology to enhance analgesic efficacy while eliminating unwanted side effects.Long-term Morphine-treated Rats are more Sensitive to Antinociceptive Effect of Diclofenac than the Morphine-naive rats.Endomorphins: potential roles and therapeutic indications in the development of opioid peptide analgesic drugs.Discovery of Novel Multifunctional Ligands with μ/δ Opioid Agonist/Neurokinin-1 (NK1) Antagonist Activities for the Treatment of Pain.Inhibition of neurokinin-1-substance P receptor and prostanoid activity prevents and reverses the development of morphine tolerance in vivo and the morphine-induced increase in CGRP expression in cultured dorsal root ganglion neurons.Rewarding effects of opiates are absent in mice lacking the receptor for substance P.
P2860
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P2860
RP 67580, a selective antagonist of neurokinin-1 receptors, modifies some of the naloxone-precipitated morphine withdrawal signs in rats.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
RP 67580, a selective antagoni ...... hine withdrawal signs in rats.
@en
RP 67580, a selective antagoni ...... hine withdrawal signs in rats.
@nl
type
label
RP 67580, a selective antagoni ...... hine withdrawal signs in rats.
@en
RP 67580, a selective antagoni ...... hine withdrawal signs in rats.
@nl
prefLabel
RP 67580, a selective antagoni ...... hine withdrawal signs in rats.
@en
RP 67580, a selective antagoni ...... hine withdrawal signs in rats.
@nl
P2093
P1433
P1476
RP 67580, a selective antagoni ...... hine withdrawal signs in rats.
@en
P2093
B P Roques
D Girdlestone
R Maldonado
P304
P356
10.1016/0304-3940(93)90457-V
P407
P577
1993-06-01T00:00:00Z