Tristetraprolin regulates interleukin-6 expression through p38 MAPK-dependent affinity changes with mRNA 3' untranslated region. - Wikidata - awgldk - TriplyDB

Tristetraprolin regulates interleukin-6 expression through p38 MAPK-dependent affinity changes with mRNA 3' untranslated region.

Tristetraprolin regulates interleukin-6 expression through p38 MAPK-dependent affinity changes with mRNA 3' untranslated region.

http://www.wikidata.org/entity/Q42279904

about

The control of inflammation via the phosphorylation and dephosphorylation of tristetraprolin: a tale of two phosphatases The G protein-coupled receptor GALR2 promotes angiogenesis in head and neck cancer.A balancing act: RNA binding protein HuR/TTP axis in endometriosis patients.Downregulation of the AU-rich RNA-binding protein ZFP36 in chronic HBV patients: implications for anti-inflammatory therapy.MAPK-activated protein kinase 2-deficiency causes hyperacute tumor necrosis factor-induced inflammatory shock.MicroRNA-let-7a expression is increased in the mesangial cells of NZB/W mice and increases IL-6 production in vitro.MAPK usage in periodontal disease progression.Dominant Suppression of Inflammation via Targeted Mutation of the mRNA Destabilizing Protein Tristetraprolin.MicroRNA-9 promotion of interleukin-6 expression by inhibiting monocyte chemoattractant protein-induced protein 1 expression in interleukin-1β-stimulated human chondrocytes RNA-stabilizing proteins as molecular targets in cardiovascular pathologies.Placental-mediated increased cytokine response to lipopolysaccharides: a potential mechanism for enhanced inflammation susceptibility of the preterm fetus Sustained mitogen-activated protein kinase activation with Aggregatibacter actinomycetemcomitans causes inflammatory bone loss miR-139 modulates MCPIP1/IL-6 expression and induces apoptosis in human OA chondrocytes.Enhanced stability of tristetraprolin mRNA protects mice against immune-mediated inflammatory pathologies.LPS-induced production of TNF-α and IL-6 in mast cells is dependent on p38 but independent of TTP Inactivation or loss of TTP promotes invasion in head and neck cancer via transcript stabilization and secretion of MMP9, MMP2, and IL-6.Arid5a controls IL-6 mRNA stability, which contributes to elevation of IL-6 level in vivo Tristetraprolin-driven regulatory circuit controls quality and timing of mRNA decay in inflammation.Tristetraprolin (TTP): interactions with mRNA and proteins, and current thoughts on mechanisms of action.Tristetraprolin: roles in cancer and senescence.Post-transcriptional gene regulation by RNA-binding proteins in vascular endothelial dysfunction.Extracellular vesicles as immune mediators in response to kidney injury.Regulation of the Expression of Heparan Sulfate 3-O-Sulfotransferase 3B (HS3ST3B) by Inflammatory Stimuli in Human Monocytes.TLR4-induced NF-κB and MAPK signaling regulate the IL-6 mRNA stabilizing protein Arid5a RNA-binding proteins in immune regulation: a focus on CCCH zinc finger proteins.An Ancient Family of RNA-Binding Proteins: Still Important!Regulation of mRNA stability by CCCH-type zinc-finger proteins in immune cells.Depletion of tristetraprolin in breast cancer cells increases interleukin-16 expression and promotes tumor infiltration with monocytes/macrophages.An RNA element in human interleukin 6 confers escape from degradation by the gammaherpesvirus SOX protein.The Role of Mitogen-Activated Protein Kinase-Activated Protein Kinases (MAPKAPKs) in Inflammation.Multilevel regulation of HIF-1 signaling by TTP.Gain-of-Function Mutation of Tristetraprolin Impairs Negative Feedback Control of Macrophages In Vitro yet Has Overwhelmingly Anti-Inflammatory Consequences In Vivo.Activation of p38 signaling increases utrophin A expression in skeletal muscle via the RNA-binding protein KSRP and inhibition of AU-rich element-mediated mRNA decay: implications for novel DMD therapeutics.Luteolin: A Flavonoid that Has Multiple Cardio-Protective Effects and Its Molecular Mechanisms.Aryl hydrocarbon receptor inhibits inflammation in DSS‑induced colitis via the MK2/p‑MK2/TTP pathway.Endonuclease Regnase-1/Monocyte chemotactic protein-1-induced protein-1 (MCPIP1) in controlling immune responses and beyond.Luteolin inhibits inflammatory responses via p38/MK2/TTP-mediated mRNA stability.

P2860

Q28076811-2B50DCE7-A985-4455-9EC7-00D47F40272A Q33623170-8F6AA726-CD9E-4268-8D7F-1C4969B44876 Q33919012-CDD4DA8E-70FF-4A08-86DA-902CA3AEFF79 Q34200816-DD734B4F-AB3C-4005-90EA-8D7D3523A9A2 Q35237725-2D6D02DE-745E-4FE9-8FAF-BF7CFADECA54 Q35601698-0B2CE3FA-2EA9-4C84-9C40-13B15BE95C3F Q35725536-962279B9-8701-4276-8622-BE7090CE9D10 Q35757055-C1C651F3-DAA0-43B9-B723-0ABD217FF523 Q35901101-0F754342-10EF-4DA4-A0F3-2E876B475011 Q35984488-05DA048B-5C33-4C5E-A663-D701401D5729 Q36175247-ECC04316-436E-4FEB-8B4D-0998E9E7530C Q36235672-8B081294-FB08-45B6-8AF0-59E4F90ECDE9 Q36356966-B2B6CFAA-94AE-4204-9BBB-224FC459F981 Q36607631-3DA35EB1-C418-4A74-815C-83A2E44FE984 Q36668282-0DC351DB-301F-459C-A60D-A40EB6A68496 Q36675764-5F9C4B95-4B18-45C0-9DC0-397612D8E4BD Q36915432-7AD6FA05-C1B4-422A-A3AA-527B50442548 Q37080841-BB6C975F-A6B1-4B63-97EE-6C8B343ED384 Q37119721-54028090-D622-43B4-A33B-853EA5C7123C Q37990333-855B4DB3-C59D-41C7-BDA1-F44791950EE6 Q38238033-295039FE-A519-4266-869C-441DAB696226 Q38601736-696E7372-D89D-4E27-B6C7-5245F0DB3BF9 Q38819007-E796F093-AA63-497E-BA07-284C4FC90AF1 Q38975045-C62602F4-059A-44E2-A058-9CE082C86C92 Q39042850-DC6488E5-97BA-4C7F-B6B3-177344E1A605 Q39092491-6125D376-5D9E-4054-A5C1-AE8D5FBF91FF Q39215435-14DF192A-064D-41D1-8FD6-16DA5AD5A904 Q39225975-1885EB15-C5B2-4ACF-9986-06C23F28D904 Q39793622-52C39C57-28EA-4C0A-9F1F-3B6D93C2AB15 Q41887469-D7C90DF8-42C5-4122-92EC-429592CEC134 Q42039351-D10BCE4A-3812-4361-B171-B3F650629B2F Q42251092-DB921CC2-3529-44F6-BF16-2931CEEAC1F8 Q45328178-F39FA4D1-42BD-4292-9FD8-EB9C6DE11F01 Q47163455-AF62BD74-801C-4793-959B-3910759A90D8 Q47329135-CF60A612-1276-43A5-A3B3-2AB241E19A47 Q47773805-1D2A89F8-C5C0-47C0-9458-9FD80C42A042 Q50848206-B3A5F0C6-2552-445D-A7C6-B07ED20BD800

P2860

Tristetraprolin regulates interleukin-6 expression through p38 MAPK-dependent affinity changes with mRNA 3' untranslated region.

http://www.wikidata.org/entity/Q42279904

description

2011 nî lūn-bûn

@nan

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

2011年论文

@zh

2011年论文

@zh-cn

name

Tristetraprolin regulates inte ...... h mRNA 3' untranslated region.

@en

Tristetraprolin regulates inte ...... h mRNA 3' untranslated region.

@nl

type

label

Tristetraprolin regulates inte ...... h mRNA 3' untranslated region.

@en

Tristetraprolin regulates inte ...... h mRNA 3' untranslated region.

@nl

prefLabel

Tristetraprolin regulates inte ...... h mRNA 3' untranslated region.

@en

Tristetraprolin regulates inte ...... h mRNA 3' untranslated region.

@nl

P1433

Q42279904-DB246A31-E70F-4586-88B0-52DC44105A38

P1476

Q42279904-862E4771-B8EE-4871-875E-578D9313915D

P2093

Q42279904-0269A861-D109-4CA6-9A79-E77783F73306

Q42279904-2987EB30-0D7A-4D87-BD13-6413D04D75B8

Q42279904-6694C127-9B9C-48B9-B72B-4E64C35749DF

Q42279904-8650E8B8-E638-4EFA-A734-EFE35D869B20

P2860

Q42279904-0F599116-F3C3-4B54-B35F-71213CF8D1E1

Q42279904-11032052-EB23-4454-B0DB-1EC5021483A4

Q42279904-12AD4534-C84B-4F84-BCA7-E98604AD0519

Q42279904-12D7DC29-B1B3-45ED-8AEC-35B5FA217E2A

Q42279904-19C3B723-0A22-41B3-842B-6C44B71B4E84

Q42279904-1EB366F0-3A7A-444E-BF11-8295F99DD7DF

Q42279904-222F18FE-E1A7-4971-A0D2-34B19CB38205

Q42279904-2845722D-9B4E-491F-B4DC-FA007B35E778

Q42279904-28E60ACD-39CA-4D02-B68D-C27FAEDC2798

Q42279904-2CD98820-0A20-4A5D-8F99-A30F566020DB

P304

Q42279904-98DB8EC2-4C8D-4E8A-9FA2-D233D01FF87C

P31

Q42279904-47FDEF91-9510-4E89-B846-0C89ED9943D1

P356

Q42279904-24831F61-AEA9-46D2-8334-F8EC78466A9F

P433

Q42279904-95B22A61-A75A-466E-B94E-2837EB5FC450

P478

Q42279904-729EBE60-201F-4816-AB35-37EF79B9961C

P577

Q42279904-BC6A8402-EC20-4139-97B8-A202BD420D2B

P5875

Q42279904-C4FF5337-B9C4-4439-85DF-2429F819B7AB

P698

Q42279904-98CECD3E-034E-4C01-ACC3-EFDDEDE9FB85

P921

Q42279904-a105c22c-2103-494a-ae87-812c6d328753

P932

Q42279904-29D3F879-87D7-46A4-A4CC-B79971A69DF1

P356

P1433

Journal of Interferon and Cytokine Research

P1476

Tristetraprolin regulates inte ...... h mRNA 3' untranslated region.

@en

P2093

Keith L Kirkwood

http://www.w3.org/2001/XMLSchema#string

Min Liu

http://www.w3.org/2001/XMLSchema#string

Nisha J D'Silva

http://www.w3.org/2001/XMLSchema#string

Wenpu Zhao

http://www.w3.org/2001/XMLSchema#string

P2860

Evidence that tristetraprolin binds to AU-rich elements and promotes the deadenylation and destabilization of tumor necrosis factor alpha mRNA.

AU binding proteins recruit the exosome to degrade ARE-containing mRNAs

Cytoplasmic localization of tristetraprolin involves 14-3-3-dependent and -independent mechanisms

MK2-induced tristetraprolin:14-3-3 complexes prevent stress granule association and ARE-mRNA decay

Feedback inhibition of macrophage tumor necrosis factor-alpha production by tristetraprolin

Functional cloning of BRF1, a regulator of ARE-dependent mRNA turnover.

Recruitment and activation of mRNA decay enzymes by two ARE-mediated decay activation domains in the proteins TTP and BRF-1

Decreased sensitivity of tristetraprolin-deficient cells to p38 inhibitors suggests the involvement of tristetraprolin in the p38 signaling pathway

Mitogen-activated protein kinase p38 controls the expression and posttranslational modification of tristetraprolin, a regulator of tumor necrosis factor alpha mRNA stability

Roles of AUF1 isoforms, HuR and BRF1 in ARE-dependent mRNA turnover studied by RNA interference

P304

629-637

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1089/JIR.2010.0154

http://www.w3.org/2001/XMLSchema#string

P433

8

http://www.w3.org/2001/XMLSchema#string

P478

31

http://www.w3.org/2001/XMLSchema#string

P577

2011-04-03T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

50986108

http://www.w3.org/2001/XMLSchema#string

P698

21457063

http://www.w3.org/2001/XMLSchema#string

P921

P932

3151618

http://www.w3.org/2001/XMLSchema#string