Genetic polymorphisms in human CYP2A6 gene causing impaired nicotine metabolism
about
PharmGKB summary: very important pharmacogene information for cytochrome P-450, family 2, subfamily A, polypeptide 6Precision Medicine for Tobacco Dependence: Development and Validation of the Nicotine Metabolite RatioPreliminary investigation of the contribution of CYP2A6, CYP2B6, and UGT1A9 polymorphisms on artesunate-mefloquine treatment response in Burmese patients with Plasmodium falciparum malaria.A novel CYP2A6 allele (CYP2A6*35) resulting in an amino-acid substitution (Asn438Tyr) is associated with lower CYP2A6 activity in vivo.A novel validated procedure for the determination of nicotine, eight nicotine metabolites and two minor tobacco alkaloids in human plasma or urine by solid-phase extraction coupled with liquid chromatography-electrospray ionization-tandem mass spectAssociation of CYP2A6*4 with susceptibility of lung cancer: a meta-analysis.CYP2A6 and ERCC1 polymorphisms correlate with efficacy of S-1 plus cisplatin in metastatic gastric cancer patientsCYP2A6 and CYP2B6 genetic variation and its association with nicotine metabolism in South Western Alaska Native peopleCYP2A6 polymorphisms: is there a role for pharmacogenomics in preventing coumarin-induced hepatotoxicity in lymphedema patients?Genetic variability in CYP2A6 and the pharmacokinetics of nicotine.Past and future applications of CYP450-genetic polymorphisms for biomonitoring of environmental toxicants.CYP2A6 polymorphisms and risk for tobacco-related cancers.Dose-finding study on adjuvant chemotherapy with S-1 plus oxaliplatin for gastric cancer.Polymorphic metabolism by functional alterations of human cytochrome P450 enzymes.Distribution of polymorphic variants of CYP2A6 and their involvement in nicotine addiction.Estimation of urinary cotinine cut-off points distinguishing non-smokers, passive and active smokers.A nicotine C-oxidase gene (CYP2A6) polymorphism important for promoter activity.Isoflavones inhibit nicotine C-oxidation catalyzed by human CYP2A6.Novel and established CYP2A6 alleles impair in vivo nicotine metabolism in a population of Black African descent.Novel human CYP2A6 alleles confound gene deletion analysis.CYP2A6 genetic polymorphisms and correlation with smoking status in Brazilians.CYP2A6 deletion polymorphism is associated with decreased susceptibility of lung cancer in Asian smokers: a meta-analysis.Differences between Spaniards and Ecuadorians in CYP2A6 allele frequencies: comparison with other populations.CYP2A6 gene polymorphism and personality traits for NEO-FFI on the smoking behavior of youths.Gene, ethnic and gender influences predisposition of adverse drug reactions to artesunate among Malaysians.Association of genetic polymorphisms CYP2A6*2 rs1801272 and CYP2A6*9 rs28399433 with tobacco-induced lung Cancer: case-control study in an Egyptian population.CYP2A6 polymorphisms in Malays, Chinese and Indians.
P2860
Q27012807-13180F57-67B3-4057-8C89-743C4FBB504DQ33821233-1A82A53C-220E-4E49-9F2C-544AF07B2694Q34015980-1ADFAB32-419B-43B9-8159-EF859CBB37DBQ34068238-04E27B03-5656-4AC2-AE55-8B0F936FF20EQ34286978-C0B72B8C-0F3F-4F6B-AC9B-C99619C908C5Q34667734-022F05A2-7378-4B3C-AF5B-3BBE8F511A38Q34745772-36B340BD-D666-46B5-AEBE-12618950FDABQ35949266-91F0AFD4-C319-4441-B628-3D12FD5E25DDQ36730627-96FEC28F-A84A-446F-9DC6-ADBA2A8C95FBQ36989832-D1072BE8-9257-43E9-8EBA-05552282DFAEQ37000474-20CD5A06-9C08-4FB8-A624-ECFDDE2623D8Q37329175-CD8C0A8F-9454-4D56-975B-710111244A9DQ37561374-3003528D-A2F9-4B3E-8667-8873E1B8E6F2Q37964573-46D876DF-1FA5-4A66-9017-8B65D28F0D1FQ38683483-2CB73931-F336-4E88-B350-03DE69738872Q39808918-A1A02B30-EA99-478E-B925-ADCBB7B3AC1FQ40587899-D6BEC6DC-BA9A-410B-B65D-330B6611B0C0Q42491133-C2DD4D92-EB2C-411C-BC64-CDDEC15DB9C0Q43597583-B5BF2771-3B04-4ED0-8E70-8E0A7C94A1E2Q44957920-BFE6FE8F-8AF0-4965-B7CC-F33A861C97D2Q45144875-3D3FF598-E68E-4D93-85FC-C58AC65F1C6EQ45766133-4AA208A4-082D-465B-B382-5E7C160D6137Q46436451-A0D1F3BA-7ADB-4D0A-9E96-0AD362E2B735Q46952411-A993C633-03D6-4C20-B555-EC18EBA54117Q47575351-712A4924-C240-4880-A7A4-A4EFF9B18B97Q53686438-0D13AD65-277C-4E04-B8F1-E3DED634C9F3Q54588559-7D04CBC9-FDE3-4348-8270-FD7FDAE12BB1
P2860
Genetic polymorphisms in human CYP2A6 gene causing impaired nicotine metabolism
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Genetic polymorphisms in human CYP2A6 gene causing impaired nicotine metabolism
@en
Genetic polymorphisms in human CYP2A6 gene causing impaired nicotine metabolism
@nl
type
label
Genetic polymorphisms in human CYP2A6 gene causing impaired nicotine metabolism
@en
Genetic polymorphisms in human CYP2A6 gene causing impaired nicotine metabolism
@nl
prefLabel
Genetic polymorphisms in human CYP2A6 gene causing impaired nicotine metabolism
@en
Genetic polymorphisms in human CYP2A6 gene causing impaired nicotine metabolism
@nl
P2093
P2860
P1476
Genetic polymorphisms in human CYP2A6 gene causing impaired nicotine metabolism
@en
P2093
Jun-Tack Kwon
Miki Nakajima
Ryoko Yoshida
Tsuyoshi Yokoi
Yuki Watanabe
P2860
P304
P356
10.1046/J.1365-2125.2002.01667.X
P407
P577
2002-11-01T00:00:00Z