Practical method for targeted disruption of cilia-related genes by using CRISPR/Cas9-mediated, homology-independent knock-in system.

Practical method for targeted disruption of cilia-related genes by using CRISPR/Cas9-mediated, homology-independent knock-in system.

Item
http://www.wikidata.org/entity/Q42292411
Ciliary entry of KIF17 is dependent on its binding to the IFT-B complex via IFT46-IFT56 as well as on its nuclear localization signal.Evaluation of ATM heterozygous mutations underlying individual differences in radiosensitivity using genome editing in human cultured cells.The CEP19-RABL2 GTPase Complex Binds IFT-B to Initiate Intraflagellar Transport at the Ciliary Base.RABL2 interacts with the intraflagellar transport-B complex and CEP19 and participates in ciliary assembly.In vivo genome editing via the HITI method as a tool for gene therapy.Cystine uptake through the cystine/glutamate antiporter xCT triggers glioblastoma cell death under glucose deprivation.Ciliary protein trafficking mediated by IFT and BBSome complexes with the aid of kinesin-2 and dynein-2 motors.Updated summary of genome editing technology in human cultured cells linked to human genetics studies.Development of versatile non-homologous end joining-based knock-in module for genome editing.Robust interaction of IFT70 with IFT52-IFT88 in the IFT-B complex is required for ciliogenesis.BBS1 is involved in retrograde trafficking of ciliary GPCRs in the context of the BBSome complex.Off and back-on again: a tumor suppressor's tale.
P2860

Practical method for targeted disruption of cilia-related genes by using CRISPR/Cas9-mediated, homology-independent knock-in system.

Item
http://www.wikidata.org/entity/Q42292411
description
2017 nî lūn-bûn
@nan
2017年の論文
@ja
2017年論文
@yue
2017年論文
@zh-hant
2017年論文
@zh-hk
2017年論文
@zh-mo
2017年論文
@zh-tw
2017年论文
@wuu
2017年论文
@zh
2017年论文
@zh-cn
name
Practical method for targeted ...... y-independent knock-in system.
@en
Practical method for targeted ...... y-independent knock-in system.
@nl
type
label
Practical method for targeted ...... y-independent knock-in system.
@en
Practical method for targeted ...... y-independent knock-in system.
@nl
prefLabel
Practical method for targeted ...... y-independent knock-in system.
@en
Practical method for targeted ...... y-independent knock-in system.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698
P921
P932
P356
P1433
P1476
Practical method for targeted ...... y-independent knock-in system.
@en
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698
P921
P932