about
Intensive pharmacological immunosuppression allows for repetitive liver gene transfer with recombinant adenovirus in nonhuman primatesAlphavirus vectors for cancer therapy.Non-viral amplification systems for gene transfer: vectors based on alphaviruses.Neoadjuvant administration of Semliki Forest virus expressing interleukin-12 combined with attenuated Salmonella eradicates breast cancer metastasis and achieves long-term survival in immunocompetent mice.Virotherapy, gene transfer and immunostimulatory monoclonal antibodies.Semliki forest virus expressing interleukin-12 induces antiviral and antitumoral responses in woodchucks with chronic viral hepatitis and hepatocellular carcinoma.Recent patents on alphavirus protein expression and vector production.Molecular characterization of transmissible gastroenteritis coronavirus defective interfering genomes: packaging and heterogeneity.Gene therapy approaches against cancer using in vivo and ex vivo gene transfer of interleukin-12.Long noncoding RNA EGOT negatively affects the antiviral response and favors HCV replication.Capsid-deficient alphaviruses generate propagative infectious microvesicles at the plasma membrane.Virotherapy with a Semliki Forest Virus-Based Vector Encoding IL12 Synergizes with PD-1/PD-L1 Blockade.Strict requirement for vector-induced type I interferon in efficacious antitumor responses to virally encoded IL12.A quick and efficient method to generate mammalian stable cell lines based on a novel inducible alphavirus DNA/RNA layered system.A Simple and Efficient In Vivo Non-viral RNA Transfection Method for Labeling the Whole Axonal Tree of Individual Adult Long-Range Projection Neurons.A Semliki forest virus vector engineered to express IFNα induces efficient elimination of established tumors.Two-helper RNA system for production of recombinant Semliki forest virus particles.Replication and packaging of transmissible gastroenteritis coronavirus-derived synthetic minigenomesA novel system for the production of high levels of functional human therapeutic proteins in stable cells with a Semliki Forest virus noncytopathic vector.Development of a new noncytopathic Semliki Forest virus vector providing high expression levels and stability.A conserved coronavirus epitope, critical in virus neutralization, mimicked by internal-image monoclonal anti-idiotypic antibodies.Increased efficacy and safety in the treatment of experimental liver cancer with a novel adenovirus-alphavirus hybrid vector.The spike protein of transmissible gastroenteritis coronavirus controls the tropism of pseudorecombinant virions engineered using synthetic minigenomes.Enhancing immune responses using suicidal DNA vaccines.Development of protection against coronavirus induced diseases. A review.Short-term intratumoral interleukin-12 expressed from an alphaviral vector is sufficient to induce an efficient antitumoral response against spontaneous hepatocellular carcinomas.Neurotropic alphaviruses can propagate without capsid.Complete genome sequence of transmissible gastroenteritis coronavirus PUR46-MAD clone and evolution of the purdue virus cluster.Immunology and gene therapy: shoulder to shoulder into the fray.Antigenic homology among coronaviruses related to transmissible gastroenteritis virus.Structure and encapsidation of transmissible gastroenteritis coronavirus (TGEV) defective interfering genomes.Biodistribution and tumor infectivity of semliki forest virus vectors in mice: effects of re-administration.Immunization with recombinant Semliki Forest virus induces protection against influenza challenge in mice.A continuous epitope from transmissible gastroenteritis virus S protein fused to E. coli heat-labile toxin B subunit expressed by attenuated Salmonella induces serum and secretory immunity.Transcriptomic effects of Tet-on and mifepristone-inducible systems in mouse liver.Characterization of transmissible gastroenteritis coronavirus S protein expression products in avirulent S. typhimurium delta cya delta crp: persistence, stability and immune response in swine.Induction of transmissible gastroenteritis coronavirus specific immune responses using vectors with enteric tropism.Induction of an immune response to transmissible gastroenteritis coronavirus using vectors with enteric tropism.Residues involved in the antigenic sites of transmissible gastroenteritis coronavirus S glycoproteinGene therapy for progressive familial intrahepatic cholestasis type 3 in a clinically relevant mouse model
P50
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P50
description
hulumtues
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հետազոտող
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Cristian Smerdou
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Cristian Smerdou
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Cristian Smerdou
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Cristian Smerdou
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Cristian Smerdou
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Cristian Smerdou
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Cristian Smerdou
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Cristian Smerdou
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Cristian Smerdou
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Cristian Smerdou Picazo
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Cristian Smerdou
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Cristian Smerdou
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Cristian Smerdou
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Cristian Smerdou
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Cristian Smerdou
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P106
P1153
6602856664
P21
P31
P496
0000-0002-6861-6579