about
Boron cluster-based development of potent nonsecosteroidal vitamin D receptor ligands: direct observation of hydrophobic interaction between protein surface and carboraneStructures of histone methyltransferase SET7/9 in complexes with adenosylmethionine derivativesIdentification of Cyproheptadine as an Inhibitor of SET Domain Containing Lysine Methyltransferase 7/9 (Set7/9) That Regulates Estrogen-Dependent TranscriptionThe fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesityA Modified Murine Embryonic Stem Cell Test for Evaluating the Teratogenic Effects of Drugs on Early EmbryogenesisValidation of chemical compound library screening for transcriptional co-activator with PDZ-binding motif inhibitors using GFP-fused transcriptional co-activator with PDZ-binding motifRetinoic acid imprints gut-homing specificity on T cellsSynergistic potentiation of thiazolidinedione-induced ST 13 preadipocyte differentiation by RAR synergists.Development of a library of 6-arylcoumarins as candidate fluorescent sensors.In vitro murine spermatogenesis in an organ culture system.Retinoid X receptor gamma signaling accelerates CNS remyelination.Inhibition of mammary carcinoma cell growth by RXR is mediated by the receptor's oligomeric switch.Synthesis of soluble aromatic multilayered tetra(m-phenylurea) and analysis of its helical conformation in various solvents.Retinoic acid induces expression of the thyroid hormone transporter, monocarboxylate transporter 8 (Mct8).Development of nonsteroidal glucocorticoid receptor modulators based on N-benzyl-N-(4-phenoxyphenyl)benzenesulfonamide scaffold.Genetic and pharmacological evidence that a retinoic acid cannot be the RXR-activating ligand in mouse epidermis keratinocytes.Chemical library screening for WNK signalling inhibitors using fluorescence correlation spectroscopy.Retinoic acid receptor signaling is required to maintain glucose-stimulated insulin secretion and β-cell mass.Discovery of Novel SPAK Inhibitors That Block WNK Kinase Signaling to Cation Chloride Transporters.Effects of RXR Agonists on Cell Proliferation/Apoptosis and ACTH Secretion/Pomc Expression.The mevalonate pathway regulates primitive streak formation via protein farnesylationRetinoid derivative Tp80 exhibits anti-hepatitis C virus activity through restoration of GI-GPx expression.Synthetic retinoids: recent developments concerning structure and clinical utility.Development of WNK signaling inhibitors as a new class of antihypertensive drugs.Molecular mechanism by which acyclic retinoid induces nuclear localization of transglutaminase 2 in human hepatocellular carcinoma cellsThe retinoic acid receptor agonist Am80 increases mucosal inflammation in an IL-6 dependent manner during Trichuris muris infection.Thyromimetics: a review of recent reports and patents (2004 - 2009).Screening with a novel cell-based assay for TAZ activators identifies a compound that enhances myogenesis in C2C12 cells and facilitates muscle repair in a muscle injury model.Differential modulation of PI3-kinase/Akt pathway during all-trans retinoic acid- and Am80-induced HL-60 cell differentiation revealed by DNA microarray analysis.9-cis Retinoic acid modulates myotrophin expression and its miR in physiological and pathophysiological cell models.Down-regulation of histone deacetylase 4, -5 and -6 as a mechanism of synergistic enhancement of apoptosis in human lung cancer cells treated with the combination of a synthetic retinoid, Am80 and green tea catechin.All trans-retinoic acid analogs promote cancer cell apoptosis through non-genomic Crabp1 mediating ERK1/2 phosphorylation.Development of 6-arylcoumarins as nonsteroidal progesterone antagonists. Structure-activity relationships and fluorescence properties.Design and synthesis of 4-benzyl-1-(2H)-phthalazinone derivatives as novel androgen receptor antagonists.A new cell-based assay to evaluate myogenesis in mouse myoblast C2C12 cells.A cell-based screening for TAZ activators identifies ethacridine, a widely used antiseptic and abortifacient, as a compound that promotes dephosphorylation of TAZ and inhibits adipogenesis in C3H10T1/2 cells.Development of 1,3-diphenyladamantane derivatives as nonsteroidal progesterone receptor antagonists.Retinoic acid receptor-α up-regulates proopiomelanocortin gene expression in AtT20 corticotroph cells.Design and Synthesis of 4-(4-Benzoylaminophenoxy)phenol Derivatives As Androgen Receptor Antagonists.Increased hydrophobicity and estrogenic activity of simple phenols with silicon and germanium-containing substituents.
P50
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Hiroyuki Kagechika
@ast
Hiroyuki Kagechika
@en
Hiroyuki Kagechika
@es
Hiroyuki Kagechika
@nl
Hiroyuki Kagechika
@sl
type
label
Hiroyuki Kagechika
@ast
Hiroyuki Kagechika
@en
Hiroyuki Kagechika
@es
Hiroyuki Kagechika
@nl
Hiroyuki Kagechika
@sl
prefLabel
Hiroyuki Kagechika
@ast
Hiroyuki Kagechika
@en
Hiroyuki Kagechika
@es
Hiroyuki Kagechika
@nl
Hiroyuki Kagechika
@sl
P106
P1153
26643532400
P21
P31
P496
0000-0002-6747-1013
P569
2000-01-01T00:00:00Z