Discovery and characterization of small molecules targeting the DNA-binding ETS domain of ERG in prostate cancer.

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Prostatic cancers: understanding their molecular pathology and the 2016 WHO classification.Fishing for cures: The alLURE of using zebrafish to develop precision oncology therapies.Recent Advances in Prostate Cancer Treatment and Drug Discovery.

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P2860

Discovery and characterization of small molecules targeting the DNA-binding ETS domain of ERG in prostate cancer.

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2017 nî lūn-bûn

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2017年の論文

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2017年論文

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Discovery and characterization ...... ain of ERG in prostate cancer.

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Discovery and characterization ...... ain of ERG in prostate cancer.

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Discovery and characterization ...... ain of ERG in prostate cancer.

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Discovery and characterization ...... ain of ERG in prostate cancer.

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Discovery and characterization ...... ain of ERG in prostate cancer.

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Discovery and characterization ...... ain of ERG in prostate cancer.

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P1476

Discovery and characterization ...... ain of ERG in prostate cancer.

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Ari Kim

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Artem Cherkasov

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Cheryl Y Gregory-Evans

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Clement Yau

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Desmond Lau

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Fariba Ghaidi

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Kush Dalal

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Lawrence P McIntosh

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Mani Roshan-Moniri

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Marta Mroczek

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P2860

Mechanistic rationale for inhibition of poly(ADP-ribose) polymerase in ETS gene fusion-positive prostate cancer

An integrated network of androgen receptor, polycomb, and TMPRSS2-ERG gene fusions in prostate cancer progression

A transcriptional repressor co-regulatory network governing androgen response in prostate cancers

A first-generation multiplex biomarker analysis of urine for the early detection of prostate cancer

DrugBank 3.0: a comprehensive resource for 'omics' research on drugs

EWS-erg and EWS-Fli1 fusion transcripts in Ewing's sarcoma and primitive neuroectodermal tumors with variant translocations

TMPRSS2-ERG gene fusion causing ERG overexpression precedes chromosome copy number changes in prostate carcinomas and paired HGPIN lesions

A small molecule inhibitor of ETV1, YK-4-279, prevents prostate cancer growth and metastasis in a mouse xenograft model

Structural and dynamic studies of the transcription factor ERG reveal DNA binding is allosterically autoinhibited

Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer.

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scholarly article

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10.18632/ONCOTARGET.17124

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English

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Takeshi Yamazaki

Mannan Nouri

Miriam S Butler

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2017-04-15T00:00:00Z

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28465491

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5522078

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Discovery and characterization of small molecules targeting the DNA-binding ETS domain of ERG in prostate cancer.

about

P2860

P2860

Discovery and characterization of small molecules targeting the DNA-binding ETS domain of ERG in prostate cancer.

description

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