Rat precision-cut liver slices predict drug-induced cholestatic injury.

about

Rat precision-cut liver slices predict drug-induced cholestatic injury.

Item

http://www.wikidata.org/entity/Q42362293

description

2017 nî lūn-bûn

@nan

2017年の論文

@ja

2017年論文

@yue

2017年論文

@zh-hant

2017年論文

@zh-hk

2017年論文

@zh-mo

2017年論文

@zh-tw

2017年论文

@wuu

2017年论文

@zh

2017年论文

@zh-cn

name

Rat precision-cut liver slices predict drug-induced cholestatic injury.

@en

Rat precision-cut liver slices predict drug-induced cholestatic injury.

@nl

type

Item

label

Rat precision-cut liver slices predict drug-induced cholestatic injury.

@en

Rat precision-cut liver slices predict drug-induced cholestatic injury.

@nl

prefLabel

Rat precision-cut liver slices predict drug-induced cholestatic injury.

@en

Rat precision-cut liver slices predict drug-induced cholestatic injury.

@nl

P1476

Rat precision-cut liver slices predict drug-induced cholestatic injury.

@en

P2093

Geny M M Groothuis

http://www.w3.org/2001/XMLSchema#string

Inge A M de Graaf

http://www.w3.org/2001/XMLSchema#string

Nashwa Soliman

http://www.w3.org/2001/XMLSchema#string

Petra van de Broek

http://www.w3.org/2001/XMLSchema#string

Samiksha Ghimire

http://www.w3.org/2001/XMLSchema#string

Viktoriia Starokozhko

http://www.w3.org/2001/XMLSchema#string

P2860

Bile acid transporters in health and disease

Drug-induced perturbations of the bile acid pool, cholestasis, and hepatotoxicity: mechanistic considerations beyond the direct inhibition of the bile salt export pump

FXR signaling in the enterohepatic system

Deciphering the nuclear bile acid receptor FXR paradigm.

Treatment of mouse liver slices with cholestatic hepatotoxicants results in down-regulation of Fxr and its target genes

Risk factors for idiosyncratic drug-induced liver injury.

Bile acid-induced necrosis in primary human hepatocytes and in patients with obstructive cholestasis.

An updated review on drug-induced cholestasis: mechanisms and investigation of physicochemical properties and pharmacokinetic parameters.

Bile Acid signaling in liver metabolism and diseases.

Cyclosporin A induced toxicity in mouse liver slices is only slightly aggravated by Fxr-deficiency and co-occurs with upregulation of pro-inflammatory genes and downregulation of genes involved in mitochondrial functions.

P2888

s00204-017-1960-7

P304

3403-3413

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1007/S00204-017-1960-7

http://www.w3.org/2001/XMLSchema#string

P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Rick Greupink

P577

2017-04-08T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

28391356

http://www.w3.org/2001/XMLSchema#string

P932

5608839

http://www.w3.org/2001/XMLSchema#string