about
Common drugs inhibit human organic cation transporter 1 (OCT1)-mediated neurotransmitter uptake.Two-dimensional NMR and all-atom molecular dynamics of cytochrome P450 CYP119 reveal hidden conformational substatesRole of protein-protein interactions in cytochrome P450-mediated drug metabolism and toxicityCytochrome P450 Enzyme Metabolites in Lead Discovery and Development.Analysis of cytochrome P450 CYP119 ligand-dependent conformational dynamics by two-dimensional NMR and X-ray crystallography.Mouse strain-dependent caspase activation during acetaminophen hepatotoxicity does not result in apoptosis or modulation of inflammation.Ligand-induced conformational heterogeneity of cytochrome P450 CYP119 identified by 2D NMR spectroscopy with the unnatural amino acid (13)C-p-methoxyphenylalanine.Spectral resolution of a second binding site for Nile Red on cytochrome P4503A4.Cysteine 98 in CYP3A4 contributes to conformational integrity required for P450 interaction with CYP reductase.Advances in the Understanding of Protein-Protein Interactions in Drug Metabolizing Enzymes through the Use of Biophysical Techniques.The role of hepatocyte nuclear factor 4-alpha in perfluorooctanoic acid- and perfluorooctanesulfonic acid-induced hepatocellular dysfunction.Digging Deeper into CYP3A Testosterone Metabolism: Kinetic, Regioselectivity, and Stereoselectivity Differences between CYP3A4/5 and CYP3A7.Aqueous synthesis of a small-molecule lanthanide chelator amenable to copper-free click chemistryTime-resolved fluorescence studies of heterotropic ligand binding to cytochrome P450 3A4Longitudinal study of insulin-like growth factor, insulin-like growth factor binding protein-3, and their polymorphisms: risk of neoplastic progression in Barrett's esophagusLigand-dependent modulation of hOCT1 transport reveals discrete ligand binding sites within the substrate translocation channelNeonatal cytochrome P450 CYP3A7: A comprehensive review of its role in development, disease, and xenobiotic metabolism
P50
Q33584577-2A187219-2AC6-4DD4-BF9F-AB8AB44B1D85Q33744590-F3DC24B5-FF3F-49E2-A820-85A7D57E5707Q34181972-7D7273E4-6F02-4BF5-9BAE-45D0103CB371Q35194778-750F364B-B651-4715-85FC-BDA0AB3A0FDFQ35450924-2910CA4C-243F-46FE-9745-8C52A852F283Q35581234-10C3BA36-0ECC-4873-92E7-9E214633C274Q37104938-C5850EB2-B510-45A7-8A8F-52A787DAE743Q38291969-F30F94EB-A6F8-4D44-9F36-0AFDCD889FB3Q41135778-94F0B107-EA20-4525-AF27-FA2667A8AE0FQ41333940-0D8A505D-7164-43B1-8200-7F9B1EA88EFCQ42372521-FA47F5D9-3624-46BA-825D-8C5A0E0D080BQ47847421-E0494661-1F32-487A-B495-12450F42173CQ64115118-AB2B8D99-8963-4E69-97CF-FCFDECF97050Q79170221-D1E42C98-43B8-42AE-9C18-85CAE7DB6787Q79843913-FDE131D0-DA80-41B4-BBEF-D78836120013Q91107153-B4ECD0DE-44E8-4308-B84A-7769B43095C4Q92844948-E027A11E-DD89-4D7B-AF32-91A7856F891E
P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Jed N Lampe
@ast
Jed N Lampe
@en
Jed N Lampe
@es
Jed N Lampe
@nl
Jed N Lampe
@sl
type
label
Jed N Lampe
@ast
Jed N Lampe
@en
Jed N Lampe
@es
Jed N Lampe
@nl
Jed N Lampe
@sl
prefLabel
Jed N Lampe
@ast
Jed N Lampe
@en
Jed N Lampe
@es
Jed N Lampe
@nl
Jed N Lampe
@sl
P106
P31
P496
0000-0003-0794-2263