Dynamic regulation of the PR-Set7 histone methyltransferase is required for normal cell cycle progression. - Wikidata - awgldk - TriplyDB

Dynamic regulation of the PR-Set7 histone methyltransferase is required for normal cell cycle progression.

Dynamic regulation of the PR-Set7 histone methyltransferase is required for normal cell cycle progression.

http://www.wikidata.org/entity/Q42376622

about

SET8 promotes epithelial-mesenchymal transition and confers TWIST dual transcriptional activities Synthesis of lysine methyltransferase inhibitors PR-Set7 and H4K20me1: at the crossroads of genome integrity, cell cycle, chromosome condensation, and transcription Phosphorylation of epigenetic "readers, writers and erasers": Implications for developmental reprogramming and the epigenetic basis for health and disease Functional characterization of Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligases in tumorigenesis The emerging role of lysine methyltransferase SETD8 in human diseases The tumor suppressor SirT2 regulates cell cycle progression and genome stability by modulating the mitotic deposition of H4K20 methylation CRL1-FBXO11 promotes Cdt2 ubiquitylation and degradation and regulates Pr-Set7/Set8-mediated cellular migration.The SKP1-Cul1-F-box and leucine-rich repeat protein 4 (SCF-FbxL4) ubiquitin ligase regulates lysine demethylase 4A (KDM4A)/Jumonji domain-containing 2A (JMJD2A) protein.The UBC9 E2 SUMO conjugating enzyme binds the PR-Set7 histone methyltransferase to facilitate target gene repression.Down-regulation of MiR-127 facilitates hepatocyte proliferation during rat liver regeneration.Proteome identification of proteins interacting with histone methyltransferase SET8.Histone H4 lysine 20 methylation: key player in epigenetic regulation of genomic integrity.CDK1-dependent inhibition of the E3 ubiquitin ligase CRL4CDT2 ensures robust transition from S Phase to Mitosis.Genetic variation in a microRNA-502 minding site in SET8 gene confers clinical outcome of non-small cell lung cancer in a Chinese population.Spontaneous development of hepatocellular carcinoma with cancer stem cell properties in PR-SET7-deficient livers.Mechanism of CRL4(Cdt2), a PCNA-dependent E3 ubiquitin ligase Epigenetic Determinants of Erythropoiesis: Role of the Histone Methyltransferase SetD8 in Promoting Erythroid Cell Maturation and Survival A genome-wide screen identifies genes that affect somatic homolog pairing in Drosophila.A polymorphism at the miR-502 binding site in the 3' untranslated region of the SET8 gene is associated with the outcome of small-cell lung cancer.SCF(β-TRCP) promotes cell growth by targeting PR-Set7/Set8 for degradation Histone H4 Lysine 20 (H4K20) Methylation, Expanding the Signaling Potential of the Proteome One Methyl Moiety at a Time.H4K20 methylation regulates quiescence and chromatin compaction.miR-502 medaited histone methyltransferase SET8 expression is associated with outcome of esophageal squamous cell carcinoma The G2/M regulator histone demethylase PHF8 is targeted for degradation by the anaphase-promoting complex containing CDC20 Transcription and Maturation of mRNA in Dinoflagellates.A functional single nucleotide polymorphism of SET8 is prognostic for breast cancer.Molecular pathways: environmental estrogens activate nongenomic signaling to developmentally reprogram the epigenome.SET for life: biochemical activities and biological functions of SET domain-containing proteins On form and function: does chromatin packing regulate the cell cycle?The PR-Set7 binding domain of Riz1 is required for the H4K20me1-H3K9me1 trans-tail 'histone code' and Riz1 tumor suppressor function.A new regulator of the cell cycle: the PR-Set7 histone methyltransferase Epigenetic inheritance: uncontested?Context-specific regulation of cancer epigenomes by histone and transcription factor methylation.Emerging roles for chromatin as a signal integration and storage platform.Flipping the switch from g1 to s phase with e3 ubiquitin ligases Sirtuins in stress response: guardians of the genome.Cell cycle-dependent degradation of the methyltransferase SETD3 attenuates cell proliferation and liver tumorigenesis.Progress in the Development of Lysine Methyltransferase SETD8 Inhibitors.Orchestration of late events in erythropoiesis by KLF1/EKLF.

P2860

Q24339520-2BD5CE42-138F-47D4-A987-80C58F18386A Q26799953-FB6DD675-CC32-42EE-BDE9-B946CEC38DB2 Q26823191-6ABF7CEC-AFA2-4B0B-842A-2EB1ACB47AEE Q26865351-2DA9C13F-AADA-471F-B802-751FCBDFAAD2 Q26998944-436B36AC-3008-497B-9410-4D4D3836245E Q28079964-763D310A-3950-4047-AEC2-5C2D530288ED Q28286787-8595BF48-528F-467D-B186-CEE8CD11BE84 Q30414178-6E0EFC1B-5660-4372-9740-BA56338B9E82 Q30430764-3955BB02-E616-4FE9-9395-FD381967ACFC Q33987877-8F297A5E-0AAA-4F6C-B090-19957E5C1419 Q34312220-70E0B59B-FC0A-4BB6-99C6-7B9CC091D48B Q34590893-2D7874BB-06DF-448A-B211-7FE3DA9471B0 Q34647591-B7247106-3A49-4121-960B-9AD125CFA7FF Q34801657-3CFF25C6-CC3F-4F2A-A683-6AADC583B13D Q35023034-68300153-8C63-4CD2-BA97-C990C7D0BBF9 Q35090652-8598A273-70A3-4A70-93E4-1F0E29489F62 Q35237385-544B3CBD-7A4E-4BF1-B0CB-E2644B07FFD1 Q35626111-D983DF0A-D462-4B0A-9F5A-71C6734B1600 Q36065950-C8A31835-D11F-4EFA-A4A3-82835878548A Q36224408-A538B7B6-06DE-4E38-99F2-DA31161E1326 Q36379597-BA2F2F62-CAFA-44A5-97E1-2E6B481BD957 Q36745115-B66003E6-B037-4CA2-98FD-F7A8E866C6DE Q37200663-25E3E41F-7393-4221-93EE-8301F56F24A6 Q37240101-D534ACC2-81CF-45B4-B47D-9EBCE3E9DC96 Q37265019-F8666AA4-D3A4-4AB0-BE2D-01649235EE11 Q37268652-643F8C14-54A7-4540-A625-81AC1AC12195 Q37376258-879A772C-DC97-4C5E-8E6E-9F369324A6B1 Q37429937-DCBD6A6D-4E1E-4BBE-86C3-2019F92193FC Q37615671-CE6E6E6B-37E3-4D85-9058-EA13DCC89E63 Q37629350-07C5EA9B-5164-446B-95E6-C00EF03D93CE Q37680327-A01A7EF4-0768-46BE-A9E8-29A2AC1A70D7 Q37825723-9BEE91CD-AE9B-476F-8606-1C4078EF79B9 Q37842140-B51D8CB2-3557-4736-AFE4-81CF05C088D6 Q38090433-EB7D5835-F66B-4062-91AE-D5AA01B6A62E Q38092575-FCC063D2-6A52-4EE4-9C3C-E299DC6EE849 Q38103251-99EDF842-D649-454A-8502-2A81F91B3FA2 Q38133369-C5553BD7-27CD-4CDB-BF85-E1F1566F1891 Q38820105-98CC321E-8A99-4B7E-A451-A9AC516046C0 Q38895557-E357682D-474C-4D62-AFB1-886F7AAC1CBD Q39117886-197884E5-D6A1-4E89-85C9-1C075D699ACA

P2860

Dynamic regulation of the PR-Set7 histone methyltransferase is required for normal cell cycle progression.

http://www.wikidata.org/entity/Q42376622

description

2010 nî lūn-bûn

@nan

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

2010年论文

@zh

2010年论文

@zh-cn

name

Dynamic regulation of the PR-S ...... normal cell cycle progression.

@en

Dynamic regulation of the PR-S ...... normal cell cycle progression.

@nl

type

label

Dynamic regulation of the PR-S ...... normal cell cycle progression.

@en

Dynamic regulation of the PR-S ...... normal cell cycle progression.

@nl

prefLabel

Dynamic regulation of the PR-S ...... normal cell cycle progression.

@en

Dynamic regulation of the PR-S ...... normal cell cycle progression.

@nl

P1433

Q42376622-05895581-0905-48EE-97AD-F9F1E9D92F65

P1476

Q42376622-F549F458-B674-45B8-8BBF-65DA0D009527

P2093

Q42376622-005A9EF0-1DB3-4C59-98DB-6B27D5B40139

Q42376622-07281CF7-14BD-4EC1-B298-150434E05738

Q42376622-241D477E-9003-44F6-A793-ADA819D16611

Q42376622-3B3F0B29-41A5-4B60-B529-B4E807B49D9F

Q42376622-C3114C35-A6A9-4F81-881B-AB4B6061F75E

Q42376622-CEE69C35-9BDD-42B0-BDE1-7F24A2A599A1

Q42376622-D6D9EF25-BAA9-4CF1-9295-BC18C95A894C

P2860

Q42376622-036FFF55-CA38-42AE-8FF2-7C4D3DB85BF9

Q42376622-27C586F7-21E8-4B92-B8C9-CDE413E93B76

Q42376622-2AAFC090-74DA-4FF0-848F-B382E3A3316B

Q42376622-33BCBB3D-69AC-4B0B-8C76-96544AC2E25C

Q42376622-33D0F727-8321-4A5D-8CD5-BBB21AC4BD51

Q42376622-3C96151E-8826-4EA3-975E-7237EEDBE7F9

Q42376622-414D9E3D-4F45-4454-B1DB-FB16D5F4762C

Q42376622-43B39C94-0282-4884-B900-FE6804DE7944

Q42376622-4DA561B8-78AB-46BC-841B-70A04BD31587

Q42376622-51F71F25-AA1A-42DD-B270-0EC16E72C10D

P304

Q42376622-67E7FB93-1A1B-4F43-9E3F-D968410244AA

P31

Q42376622-FABD9648-4E03-40D2-9AD4-0CF748B29109

P356

Q42376622-95D48C4C-69AB-4209-8184-0B90E4CAADA0

P433

Q42376622-5CCACC1E-62C1-4651-907D-E9D25BD6B6C2

P478

Q42376622-EC0D728E-6752-41C1-B50B-1BBB3B9AFC46

P577

Q42376622-19C41837-65EF-40FF-82C4-19B451044614

P5875

Q42376622-6D99ACF3-FD6E-4635-AF0F-B92777BC1E11

P698

Q42376622-62C08EE0-FEBB-46E8-9831-1F887F5B5B1A

P932

Q42376622-D86FC6B2-40CA-4EF4-B2BB-E346EF3A3329

P356

P1433

Genes & Development

P1476

Dynamic regulation of the PR-S ...... normal cell cycle progression.

@en

P2093

Judd C Rice

http://www.w3.org/2001/XMLSchema#string

Kyoko Yokomori

http://www.w3.org/2001/XMLSchema#string

Lauren M Congdon

http://www.w3.org/2001/XMLSchema#string

Marc W Kirschner

http://www.w3.org/2001/XMLSchema#string

Shumin Wu

http://www.w3.org/2001/XMLSchema#string

Weiping Wang

http://www.w3.org/2001/XMLSchema#string

Xiangduo Kong

http://www.w3.org/2001/XMLSchema#string

P2860

L3MBTL1, a histone-methylation-dependent chromatin lock

PR-Set7 establishes a repressive trans-tail histone code that regulates differentiation

Human SFMBT is a transcriptional repressor protein that selectively binds the N-terminal tail of histone H3

Histone H4 lysine 20 monomethylation promotes transcriptional repression by L3MBTL1

A family of putative tumor suppressors is structurally and functionally conserved in humans and yeast

Modulation of p53 function by SET8-mediated methylation at lysine 382

PHF8 mediates histone H4 lysine 20 demethylation events involved in cell cycle progression

The dual-specificity phosphatase CDC14B bundles and stabilizes microtubules

Structural and functional analysis of SET8, a histone H4 Lys-20 methyltransferase

Disruption of centrosome structure, chromosome segregation, and cytokinesis by misexpression of human Cdc14A phosphatase.

P304

2531-2542

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1101/GAD.1984210

http://www.w3.org/2001/XMLSchema#string

P433

22

http://www.w3.org/2001/XMLSchema#string

P478

24

http://www.w3.org/2001/XMLSchema#string

P577

2010-10-21T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

47519835

http://www.w3.org/2001/XMLSchema#string

P698

20966048

http://www.w3.org/2001/XMLSchema#string

P932

2975929

http://www.w3.org/2001/XMLSchema#string