USP11 regulates PML stability to control Notch-induced malignancy in brain tumours.
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Cullin 3 Ubiquitin Ligases in Cancer Biology: Functions and Therapeutic ImplicationsThe function, regulation and therapeutic implications of the tumor suppressor protein, PMLEvolution of the highly networked deubiquitinating enzymes USP4, USP15, and USP11USP11 regulates p53 stability by deubiquitinating p53.Identification of RNF168 as a PML nuclear body regulatorDestabilization of Lysophosphatidic Acid Receptor 1 Reduces Cytokine Release and Protects Against Lung Injury.Regulation of XIAP Turnover Reveals a Role for USP11 in Promotion of Tumorigenesis.Ubiquitin-dependent and independent roles of SUMO in proteostasis.Ubiquitin-specific protease 11 (USP11) functions as a tumor suppressor through deubiquitinating and stabilizing VGLL4 protein.NPM1 Mutant Mediated PML Delocalization and Stabilization Enhances Autophagy and Cell Survival in Leukemic Cells.Ubiquitin-specific Protease 11 (USP11) Deubiquitinates Hybrid Small Ubiquitin-like Modifier (SUMO)-Ubiquitin Chains to Counteract RING Finger Protein 4 (RNF4).Ubiquitination of tumor suppressor PML regulates prometastatic and immunosuppressive tumor microenvironmentRegulation of XPC deubiquitination by USP11 in repair of UV-induced DNA damage.USP11 deubiquitinates RAE1 and plays a key role in bipolar spindle formation.Phosphorylated E2F1 is stabilized by nuclear USP11 to drive Peg10 gene expression and activate lung epithelial cells.Fatty Acid Synthase induced S6Kinase facilitates USP11-eIF4B complex formation for sustained oncogenic translation in DLBCL.Deubiquitylation and stabilization of p21 by USP11 is critical for cell-cycle progression and DNA damage responses.Cullin 3 targets methionine adenosyltransferase IIα for ubiquitylation-mediated degradation and regulates colorectal cancer cell proliferationIdentification and Characterization of USP7 Targets in Cancer Cells
P2860
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P2860
USP11 regulates PML stability to control Notch-induced malignancy in brain tumours.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
USP11 regulates PML stability to control Notch-induced malignancy in brain tumours.
@en
USP11 regulates PML stability to control Notch-induced malignancy in brain tumours.
@nl
type
label
USP11 regulates PML stability to control Notch-induced malignancy in brain tumours.
@en
USP11 regulates PML stability to control Notch-induced malignancy in brain tumours.
@nl
prefLabel
USP11 regulates PML stability to control Notch-induced malignancy in brain tumours.
@en
USP11 regulates PML stability to control Notch-induced malignancy in brain tumours.
@nl
P2093
P2860
P356
P1476
USP11 regulates PML stability to control Notch-induced malignancy in brain tumours
@en
P2093
Hsiang-Ching Chung
Hsin-Chieh Wu
Ruey-Hwa Chen
Sean E Lawler
Ya-Ting Wang
Ya-Wen Lin
Yu-Ching Lin
P2860
P2888
P356
10.1038/NCOMMS4214
P407
P577
2014-01-01T00:00:00Z