Controlled induction of human pancreatic progenitors produces functional beta-like cells in vitro. - Wikidata - awgldk - TriplyDB

Controlled induction of human pancreatic progenitors produces functional beta-like cells in vitro.

Controlled induction of human pancreatic progenitors produces functional beta-like cells in vitro.

http://www.wikidata.org/entity/Q42395113

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Genome-edited human stem cell-derived beta cells: a powerful tool for drilling down on type 2 diabetes GWAS biology Survival of encapsulated islets: More than a membrane story Recent Advances in Disease Modeling and Drug Discovery for Diabetes Mellitus Using Induced Pluripotent Stem Cells A programmable synthetic lineage-control network that differentiates human IPSCs into glucose-sensitive insulin-secreting beta-like cells Islet-like organoids derived from human pluripotent stem cells efficiently function in the glucose responsiveness in vitro and in vivo.Adult muscle-derived stem cells engraft and differentiate into insulin-expressing cells in pancreatic islets of diabetic mice.β-Cell Replacement Strategies: The Increasing Need for a "β-Cell Dogma".Long-Term Culture of Self-renewing Pancreatic Progenitors Derived from Human Pluripotent Stem Cells Human pluripotent stem cell differentiation to functional pancreatic cells for diabetes therapies: Innovations, challenges and future directions.Probing the missing mature β-cell proteomic landscape in differentiating patient iPSC-derived cells.Human pancreatic beta-like cells converted from fibroblasts.BMP-7 Induces Adult Human Pancreatic Exocrine-to-Endocrine Conversion.Concise Review: Markers for Assessing Human Stem Cell-Derived Implants as β-Cell Replacement in Type 1 Diabetes.An Abbreviated Protocol for In Vitro Generation of Functional Human Embryonic Stem Cell-Derived Beta-Like Cells.Pancreas lineage allocation and specification are regulated by sphingosine-1-phosphate signalling Accelerated Maturation of Human Stem Cell-Derived Pancreatic Progenitor Cells into Insulin-Secreting Cells in Immunodeficient Rats Relative to Mice.Age-Dependent Pancreatic Gene Regulation Reveals Mechanisms Governing Human β Cell Function.The transcriptomes of novel marmoset monkey embryonic stem cell lines reflect distinct genomic features.Human islets contain four distinct subtypes of β cells Insights into islet development and biology through characterization of a human iPSC-derived endocrine pancreas model.A Single-Cell Transcriptomic Map of the Human and Mouse Pancreas Reveals Inter- and Intra-cell Population Structure.An arduous journey from human pluripotent stem cells to functional pancreatic β cells.Progress and challenges in macroencapsulation approaches for type 1 diabetes (T1D) treatment: Cells, biomaterials, and devices.Centroacinar cells: At the center of pancreas regeneration.Genome Editing of Lineage Determinants in Human Pluripotent Stem Cells Reveals Mechanisms of Pancreatic Development and Diabetes.How to make insulin-producing pancreatic β cells for diabetes treatment.The role of hepatocyte nuclear factor 1β in disease and development.Revisiting the immunocytochemical detection of Neurogenin 3 expression in mouse and man.Regeneration of pancreatic insulin-producing cells by in situ adaptive cell conversion.Is Transforming Stem Cells to Pancreatic Beta Cells Still the Holy Grail for Type 2 Diabetes?The quest to make fully functional human pancreatic beta cells from embryonic stem cells: climbing a mountain in the clouds.Mass production of functional human pancreatic β-cells: why and how?β-Cell replacement as a treatment for type 1 diabetes: an overview of possible cell sources and current axes of research.GATA6 Plays an Important Role in the Induction of Human Definitive Endoderm, Development of the Pancreas, and Functionality of Pancreatic β Cells.Advances in islet encapsulation technologies.Is a β cell a β cell?All mixed up: defining roles for β-cell subtypes in mature islets.iPSC technology-based regenerative therapy for diabetes.The Nexus of Stem Cell-Derived Beta-Cells and Genome Engineering.Brief review: cell replacement therapies to treat type 1 diabetes mellitus.

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P2860

Controlled induction of human pancreatic progenitors produces functional beta-like cells in vitro.

http://www.wikidata.org/entity/Q42395113

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name

Controlled induction of human ...... onal beta-like cells in vitro.

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Controlled induction of human ...... onal beta-like cells in vitro.

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Controlled induction of human ...... onal beta-like cells in vitro.

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Controlled induction of human ...... onal beta-like cells in vitro.

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Controlled induction of human ...... onal beta-like cells in vitro.

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Controlled induction of human ...... onal beta-like cells in vitro.

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The EMBO Journal

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Controlled induction of human ...... onal beta-like cells in vitro.

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Audrey V Parent

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Gopika G Nair

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Greg L Szot

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Holger A Russ

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Jennifer J Ringler

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Leena Haataja

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Matthias Hebrok

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Mayya Shveygert

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Peter Arvan

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Sapna Puri

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P2860

Induction of human beta-cell proliferation and engraftment using a single G1/S regulatory molecule, cdk6

The unique cytoarchitecture of human pancreatic islets has implications for islet cell function

A scalable system for production of functional pancreatic progenitors from human embryonic stem cells

Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen

Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells

Generation of functional human pancreatic β cells in vitro

Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo

Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells

Efficient differentiation of human embryonic stem cells to definitive endoderm

Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors

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10.15252/EMBJ.201591058

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Robert Blelloch

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