Krüppel-like factor 4 (KLF4) inactivation in chronic lymphocytic leukemia correlates with promoter DNA-methylation and can be reversed by inhibition of NOTCH signaling.
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Inactivation of KLF4 promotes T-cell acute lymphoblastic leukemia and activates the MAP2K7 pathway.Novel tumor-suppressor function of KLF4 in pediatric T-cell acute lymphoblastic leukemia.Significance of Inactivated Genes in Leukemia: Pathogenesis and PrognosisCRISPR-ON-Mediated KLF4 overexpression inhibits the proliferation, migration and invasion of urothelial bladder cancer in vitro and in vivo.NFATC1 activation by DNA hypomethylation in chronic lymphocytic leukemia correlates with clinical staging and can be inhibited by ibrutinib.
P2860
Krüppel-like factor 4 (KLF4) inactivation in chronic lymphocytic leukemia correlates with promoter DNA-methylation and can be reversed by inhibition of NOTCH signaling.
description
2016 nî lūn-bûn
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2016年の論文
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2016年論文
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2016年論文
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2016年論文
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2016年論文
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2016年論文
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2016年论文
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2016年论文
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2016年论文
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name
Krüppel-like factor 4 (KLF4) i ...... inhibition of NOTCH signaling.
@en
type
label
Krüppel-like factor 4 (KLF4) i ...... inhibition of NOTCH signaling.
@en
prefLabel
Krüppel-like factor 4 (KLF4) i ...... inhibition of NOTCH signaling.
@en
P2093
P2860
P50
P1433
P1476
Krüppel-like factor 4 (KLF4) i ...... inhibition of NOTCH signaling.
@en
P2093
Angela Garding
Christine Wolf
Christoph Plass
Daniel Mertens
Dieter Weichenhan
Katharina Filarsky
Manuela Zucknick
Natalia Becker
Rainer Claus
P2860
P304
P356
10.3324/HAEMATOL.2015.138172
P577
2016-04-14T00:00:00Z