The α7 nicotinic receptor dual allosteric agonist and positive allosteric modulator GAT107 reverses nociception in mouse models of inflammatory and neuropathic pain.

The α7 nicotinic receptor dual allosteric agonist and positive allosteric modulator GAT107 reverses nociception in mouse models of inflammatory and neuropathic pain.

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http://www.wikidata.org/entity/Q42406043
Plasticity in Brainstem Mechanisms of Pain Modulation by Nicotinic Acetylcholine Receptors in the Rat.Allosteric modulation of α4β2* nicotinic acetylcholine receptors: Desformylflustrabromine potentiates antiallodynic response of nicotine in a mouse model of neuropathic pain.Persistent activation of α7 nicotinic ACh receptors associated with stable induction of different desensitized states.Leveraging allostery to improve G protein-coupled receptor (GPCR)-directed therapeutics: cannabinoid receptor 1 as discovery target.The interaction between alpha 7 nicotinic acetylcholine receptor and nuclear peroxisome proliferator-activated receptor-α represents a new antinociceptive signaling pathway in mice.New Insights on Neuronal Nicotinic Acetylcholine Receptors as Targets for Pain and Inflammation: A Focus on α7 nAChRs.The current agonists and positive allosteric modulators of α7 nAChR for CNS indications in clinical trials.Nicotinic acetylcholine receptors in neuropathic and inflammatory pain.Polymethoxyflavones from Nicotiana plumbaginifolia (Solanaceae) Exert Antinociceptive and Neuropharmacological Effects in Mice.Monoacylglycerol lipase inhibitors reverse paclitaxel-induced nociceptive behavior and proinflammatory markers in a mouse model of chemotherapy-induced neuropathy.α7 Nicotinic acetylcholine receptor-mediated anti-inflammatory effect in a chronic migraine rat model via the attenuation of glial cell activation.
P2860

The α7 nicotinic receptor dual allosteric agonist and positive allosteric modulator GAT107 reverses nociception in mouse models of inflammatory and neuropathic pain.

Item
http://www.wikidata.org/entity/Q42406043
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
The α7 nicotinic receptor dual ...... ammatory and neuropathic pain.
@en
The α7 nicotinic receptor dual ...... ammatory and neuropathic pain.
@nl
type
label
The α7 nicotinic receptor dual ...... ammatory and neuropathic pain.
@en
The α7 nicotinic receptor dual ...... ammatory and neuropathic pain.
@nl
prefLabel
The α7 nicotinic receptor dual ...... ammatory and neuropathic pain.
@en
The α7 nicotinic receptor dual ...... ammatory and neuropathic pain.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921
P932
P356
P1433
P1476
The α7 nicotinic receptor dual ...... lammatory and neuropathic pain
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921
P932