about
A Novel Inhibitor Prevents the Peripheral Neuroparalysis of Botulinum Neurotoxins.On the translocation of botulinum and tetanus neurotoxins across the membrane of acidic intracellular compartments.Inhibition of botulinum neurotoxins interchain disulfide bond reduction prevents the peripheral neuroparalysis of botulism.EGA Protects Mammalian Cells from Clostridium difficile CDT, Clostridium perfringens Iota Toxin and Clostridium botulinum C2 Toxin.Genomic characterization of Italian Clostridium botulinum group I strains.Semicarbazone EGA Inhibits Uptake of Diphtheria Toxin into Human Cells and Protects Cells from Intoxication.The first non Clostridial botulinum-like toxin cleaves VAMP within the juxtamembrane domain.Presynaptic endocytic factors in autophagy and neurodegeneration.Hsp90 and Thioredoxin-Thioredoxin Reductase enable the catalytic activity of Clostridial neurotoxins inside nerve terminals.Hsp90 is involved in the entry of clostridial neurotoxins into the cytosol of nerve terminals.Thioredoxin and its reductase are present on synaptic vesicles, and their inhibition prevents the paralysis induced by botulinum neurotoxins.The thioredoxin reductase--Thioredoxin redox system cleaves the interchain disulphide bond of botulinum neurotoxins on the cytosolic surface of synaptic vesicles.Erratum to "Inhibition of botulinum neurotoxins interchain disulfide bond reduction prevents the peripheral neuroparalysis of botulism" [Biochem. Pharmacol. 98 (2015) 522-530].Novel Botulinum Neurotoxins: Exploring Underneath the Iceberg Tip.
P50
Q36376074-E1356498-5ABF-4171-BFA5-E8E0ED8FDF6FQ38573906-916A7B4D-1989-42E9-A925-1E2F66FB0E4DQ40451664-C1903940-69B6-491F-9788-5F128D701DB8Q40740746-22F750ED-C0F3-47C4-B1E3-A99A52571C5FQ41407289-8209332E-457A-4681-BC5D-86FE9B9CFB37Q42107487-F7511004-4EC7-4EB6-B95C-CD2B927CE825Q42408273-4BA94C3C-8242-44AA-B39B-2AE656D47344Q47217309-0ADE1C4B-D28A-487C-A1F2-5EFE05081831Q47432235-4181DFEC-B90C-4679-81F8-E86F62DD069BQ48163816-E08CE45D-ED90-4C1C-A19D-10986A997A3CQ48543733-27CCC5DC-8B97-492E-BAB7-661D27E11240Q53446431-3763EA78-3F37-4F23-B1F3-2170C820C797Q53583886-6EA75A04-82EC-45EE-8249-4833291A3CD9Q55331839-C30D71CF-C286-4284-83A4-40459D04317A
P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Domenico Azarnia Tehran
@ast
Domenico Azarnia Tehran
@en
Domenico Azarnia Tehran
@es
Domenico Azarnia Tehran
@nl
Domenico Azarnia Tehran
@sl
type
label
Domenico Azarnia Tehran
@ast
Domenico Azarnia Tehran
@en
Domenico Azarnia Tehran
@es
Domenico Azarnia Tehran
@nl
Domenico Azarnia Tehran
@sl
prefLabel
Domenico Azarnia Tehran
@ast
Domenico Azarnia Tehran
@en
Domenico Azarnia Tehran
@es
Domenico Azarnia Tehran
@nl
Domenico Azarnia Tehran
@sl
P1053
O-3647-2016
P106
P1153
56700313400
P21
P2798
P31
P3829
P496
0000-0001-8955-7240