By interacting with the C-terminal Phe of apelin, Phe255 and Trp259 in helix VI of the apelin receptor are critical for internalization.

By interacting with the C-terminal Phe of apelin, Phe255 and Trp259 in helix VI of the apelin receptor are critical for internalization.

Item
http://www.wikidata.org/entity/Q42411890
Apelin, Elabela/Toddler, and biased agonists as novel therapeutic agents in the cardiovascular systemRole of the Vasopressin/Apelin Balance and Potential Use of Metabolically Stable Apelin Analogs in Water Metabolism Disorders.Biased signaling favoring gi over β-arrestin promoted by an apelin fragment lacking the C-terminal phenylalanineIdentification of novel Trypanosoma cruzi prolyl oligopeptidase inhibitors by structure-based virtual screening.[Pyr1]Apelin-13(1-12) Is a Biologically Active ACE2 Metabolite of the Endogenous Cardiovascular Peptide [Pyr1]Apelin-13.Bioactivity of the putative apelin proprotein expands the repertoire of apelin receptor ligands.Directed Molecular Evolution of an Engineered Gammaretroviral Envelope Protein with Dual Receptor Use Shows Stable Maintenance of Both Receptor Specificities.Molecular basis of agonist docking in a human GPR103 homology model by site-directed mutagenesis and structure-activity relationship studies.The Aplnr GPCR regulates myocardial progenitor development via a novel cell-non-autonomous, Gα(i/o) protein-independent pathway.Apelin acts in the subfornical organ to influence neuronal excitability and cardiovascular function.A Time-Resolved FRET Cell-Based Binding Assay for the Apelin Receptor.Pyrene-Apelin Conjugation Modulates Fluorophore- and Peptide-Micelle Interactions.Structure-activity relationship of novel macrocyclic biased apelin receptor agonists.Convenient Access to Fluorescent Probes by Chemoselective Acylation of Hydrazinopeptides: Application to the Synthesis of the First Far-Red Ligand for Apelin Receptor Imaging.The Metalloprotease Neprilysin Degrades and Inactivates Apelin Peptides.Apelinergic System Structure and Function.
P2860

By interacting with the C-terminal Phe of apelin, Phe255 and Trp259 in helix VI of the apelin receptor are critical for internalization.

Item
http://www.wikidata.org/entity/Q42411890
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
By interacting with the C-term ...... critical for internalization.
@en
By interacting with the C-term ...... critical for internalization.
@nl
type
label
By interacting with the C-term ...... critical for internalization.
@en
By interacting with the C-term ...... critical for internalization.
@nl
prefLabel
By interacting with the C-term ...... critical for internalization.
@en
By interacting with the C-term ...... critical for internalization.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932
P356
P1433
P1476
By interacting with the C-term ...... e critical for internalization
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932